P&O Cruises to the Mediterranean


Refine your search:
Mediterranean
Southampton | Lisbon | Alicante | Livorno | Civitavecchia | Palma de Mallorca | Casablanca | Tangier | Vigo | Southampton
06 Sep 2025
19 Nights
Mediterranean

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £203pp
Cruise Only From
Was £1749pp
Now: £1665
pp
REF: POJ514
Spain, Portugal and Canary Islands
Southampton | Funchal, Madeira | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton
06 Sep 2025
14 Nights
Atlantic Islands

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £137pp
Cruise Only From
Was £1149pp
Now: £1126
pp
REF: PON523
Mediterranean
Valletta | Ajaccio, Corsica | Livorno | Civitavecchia | Naples | Valletta
11 Sep 2025
7 Nights
Mediterranean

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £119pp
Fly Cruise From
Was £999pp
Now: £979
pp
REF: POA535
Mediterranean
Valletta | Ajaccio, Corsica | Livorno | Civitavecchia | Naples | Valletta | Piraeus | Kusadasi | Rhodes | Santorini | Valletta
11 Sep 2025
14 Nights
Mediterranean

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £248pp
Fly Cruise From
Was £2099pp
Now: £2037
pp
REF: POA535A
Mediterranean
Southampton | La Coruña | Málaga | Alicante | Toulon | Barcelona | Cádiz | Southampton
14 Sep 2025
14 Nights
Northern Europe

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £125pp
Cruise Only From
Was £1049pp
Now: £1028
pp
REF: POK519
Mediterranean
Valletta | Piraeus | Kusadasi | Rhodes | Santorini | Valletta
18 Sep 2025
7 Nights
Mediterranean

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £134pp
Fly Cruise From
Was £1119pp
Now: £1097
pp
REF: POA536
Mediterranean
Valletta | Piraeus | Kusadasi | Rhodes | Santorini | Valletta | Dubrovnik | Zadar | Split | Catania | Valletta
18 Sep 2025
14 Nights
Mediterranean

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Fly Cruise From
Was £2299pp
Now: £2243
pp
REF: POA536A
Spain, Portugal and Canary Islands
Southampton | Funchal, Madeira | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | La Coruña | Southampton
20 Sep 2025
14 Nights
Atlantic Islands

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £135pp
Cruise Only From
Was £1129pp
Now: £1106
pp
REF: PON524
Portugal And Canary Islands
Southampton | Funchal, Madeira | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Vigo | La Coruña | Southampton
20 Sep 2025
14 Nights
Atlantic Islands

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £143pp
Cruise Only From
Was £1199pp
Now: £1175
pp
REF: POG531
Mediterranean
Valletta | Dubrovnik | Zadar | Split | Catania | Valletta
25 Sep 2025
7 Nights
Mediterranean

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £123pp
Fly Cruise From
Was £1029pp
Now: £1008
pp
REF: POA537
Mediterranean
Valletta | Dubrovnik | Zadar | Split | Catania | Valletta | Civitavecchia | Livorno | Villefranche-sur-Mer | Ajaccio, Corsica | Valletta
25 Sep 2025
14 Nights
Mediterranean

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £197pp
Fly Cruise From
Was £1731pp
Now: £1616
pp
REF: POA537A
Mediterranean
Southampton | La Coruña | Málaga | Cartagena | Barcelona | Cádiz | Southampton
28 Sep 2025
13 Nights
Northern Europe

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £113pp
Cruise Only From
Was £949pp
Now: £930
pp
REF: POK520
Mediterranean
Valletta | Civitavecchia | Livorno | Villefranche-sur-Mer | Ajaccio, Corsica | Valletta
02 Oct 2025
7 Nights
Mediterranean

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £96pp
Fly Cruise From
Was £849pp
Now: £783
pp
REF: POA538
Mediterranean
Southampton | Cartagena | Cagliari | Katakolon | Corfu | Dubrovnik | Split | Messina | Gibraltar | Southampton
02 Oct 2025
19 Nights
Mediterranean

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Cruise Only From
Was £2299pp
Now: £2057
pp
REF: POR518
Mediterranean and Canary Islands
Valletta | Civitavecchia | Livorno | Villefranche-sur-Mer | Ajaccio, Corsica | Valletta | Cartagena | Tangier | Lanzarote | Santa Cruz de Tenerife
02 Oct 2025
15 Nights
Mediterranean

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £155pp
Cruise Only From
Was £1299pp
Now: £1273
pp
REF: POA538A
Mediterranean and Canary Islands
Valletta | Civitavecchia | Livorno | Villefranche-sur-Mer | Ajaccio, Corsica | Valletta | Cartagena | Tangier | Lanzarote | Santa Cruz de Tenerife | Santa Cruz de Tenerife
02 Oct 2025
16 Nights
Atlantic Islands

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £173pp
Fly Cruise From
Was £1499pp
Now: £1420
pp
REF: POA538B
Spain, Portugal and Canary Islands
Southampton | Funchal, Madeira | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Lanzarote | Cádiz | La Coruña | Southampton
03 Oct 2025
14 Nights
Atlantic Islands

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £125pp
Cruise Only From
Was £1279pp
Now: £1175
pp
REF: POB524
Spain and Portugal
Southampton | Cherbourg | Leixões | Lisbon | Vigo | Southampton
04 Oct 2025
7 Nights
Western Europe

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £76pp
Cruise Only From
Was £729pp
Now: £714
pp
REF: PON525
Mediterranean and Canary Islands
Valletta | Cartagena | Tangier | Lanzarote | Santa Cruz de Tenerife
09 Oct 2025
8 Nights
Atlantic Islands

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £78pp
Fly Cruise From
Was £749pp
Now: £734
pp
REF: POA539
Mediterranean and Canary Islands
Valletta | Cartagena | Tangier | Lanzarote | Santa Cruz de Tenerife | Santa Cruz de Tenerife
09 Oct 2025
9 Nights
Atlantic Islands

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £84pp
Fly Cruise From
Was £799pp
Now: £783
pp
REF: POA539A
Mediterranean and Canary Islands
Valletta | Cartagena | Tangier | Lanzarote | Santa Cruz de Tenerife | Santa Cruz de Tenerife | Funchal, Madeira | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife
09 Oct 2025
15 Nights
Atlantic Islands

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £125pp
Fly Cruise From
Was £1199pp
Now: £1175
pp
REF: POA539B
Mediterranean and Canary Islands
Valletta | Cartagena | Tangier | Lanzarote | Santa Cruz de Tenerife | Santa Cruz de Tenerife | Funchal, Madeira | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife | Santa Cruz de Tenerife
09 Oct 2025
16 Nights
Atlantic Islands

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £131pp
Fly Cruise From
Was £1249pp
Now: £1224
pp
REF: POA539C
Mediterranean
Southampton | La Coruña | Málaga | Barcelona | Alicante | Cádiz | Southampton
11 Oct 2025
13 Nights
Northern Europe

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £92pp
Cruise Only From
Was £949pp
Now: £861
pp
REF: POK521
Spain, Portugal and Canary Islands
Southampton | Funchal, Madeira | Santa Cruz de La Palma | Santa Cruz de Tenerife | Fuerteventura | Lanzarote | Cádiz | Lisbon | Southampton
11 Oct 2025
14 Nights
Atlantic Islands

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £119pp
Cruise Only From
Was £1139pp
Now: £1116
pp
REF: PON526
Canary Islands
Santa Cruz de Tenerife | Santa Cruz de Tenerife | Funchal, Madeira | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife
17 Oct 2025
7 Nights
Atlantic Islands

Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
ONLINE FLASH SALE! Save up to an EXTRA £50 per stateroom when you book online - ends soon!
Interest free Monthly Payments from JUST £71pp
Fly Cruise From
Was £749pp
Now: £665
pp
REF: POA540

Our Award Winning Service


Best Workplaces in Travel 2024
Best Workplaces in Travel 2024
Best Company Top 100
Best Company Top 100
Best Cruise Online Agent 2019
Best Cruise Online Agent 2019
Best Cruise Online Agent 2021
Best Cruise Online Agent 2021
TTG Top 50 Ocean Cruise Agency 2019
TTG Top 50 Ocean Cruise Agency 2019
TTG Top 50 Ocean Cruise Agency 2022
TTG Top 50 Ocean Cruise Agency 2022
Best Online Travel Agency 2022
Best Online Travel Agency 2022
Large Cruise Agency of the Year 2023
Large Cruise Agency of the Year 2023

Request a Callback

Chat Service

Live Chat

Live Chat
Call for Free