P&O Cruises from Southampton

Find Out More About P&O Cruises

P&O Cruises is one of the biggest operators of Southampton cruises, sailing to destinations across Europe and the Caribbean. Worldwide cruises from Southampton also visit a wealth of further destinations, so wherever you're looking to travel you'll find something that's right for you.


Refine your search:
Belgium And Netherlands
Southampton | Rotterdam | Rotterdam | Zeebrugge | Southampton
21 Oct 2026
5 Nights
Northern Europe

Departs from the UK
10% off classic drinks package - *on selected sailings
Interest free Monthly Payments from JUST £21pp
Cruise Only From
Was £499pp
Now: £489
pp
REF: POJ614
Spain And France
Southampton | Bilbao | La Coruña | Vigo | Cherbourg | Southampton
24 Oct 2026
7 Nights
Western Europe

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
Interest free Monthly Payments from JUST £23pp
Cruise Only From
Was £549pp
Now: £538
pp
REF: POG635
Spain France And Portugal
Southampton | Cherbourg | Leixões | Lisbon | Vigo | Southampton
24 Oct 2026
7 Nights
Western Europe

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
Interest free Monthly Payments from JUST £25pp
Cruise Only From
Was £579pp
Now: £567
pp
REF: PON628
Spain Portugal And Canary Islands
Southampton | La Coruña | Funchal, Madeira | Funchal, Madeira | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Southampton
26 Oct 2026
16 Nights
Atlantic Islands

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
Interest free Monthly Payments from JUST £52pp
Cruise Only From
Was £1229pp
Now: £1204
pp
REF: POJ615
Northern European City Escape
Southampton | Hamburg | Rotterdam | Rotterdam | Zeebrugge | Southampton
31 Oct 2026
7 Nights
Northern Europe

Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
Interest free Monthly Payments from JUST £21pp
Cruise Only From
Was £529pp
Now: £518
pp
REF: POG636

Find P&O Cruises from Southampton

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P&O Cruises from Southampton are a fantastically convenient way to explore the world, without the need to think about arranging flights. There's no need to worry about what to pack either – as long as your bags can fit into your cabin, you're welcome to bring as much luggage as you like!

Cruising from Southampton offers a variety of benefits, including dedicated parking and transfer facilities with drop-off points right next to the ship terminals. If you're looking for a change from flights and hotel stays, this could be the perfect low-stress holiday.

P&O Cruises ships sailing from Southampton

Each ship in the P&O Cruises fleet sails from Southampton, offering you the widest choice to select from, whether it's a family-friendly cruise or an adults-only sailing.

Destinations you can reach from the UK

Cruise from Southampton with P&O Cruises and you'll find a whole host of destinations just waiting to be explored. Where you can cruise to depends on the duration of your cruise:

  • Mini cruises - cruise for two to five nights and you can reach interesting European ports such as Guernsey, Amsterdam, Cherbourg and Bruges. 
  • 7-night cruises - cruise for a week and you can explore the Norwegian Fjords, Holland, France and Belgium or head south to Spain and Portugal
  • 14-night cruises - in two weeks you can cruise to Italy and back, explore the Baltics or get some winter sun in the Canary Islands
  • Long duration cruises - head transatlantic to the USA and Canada, cruise the Caribbean or push the boat out with a world cruise

Book your P&O cruise from the UK

Look ahead to sailing with P&O Cruises from Southampton and enjoy a quintessentially British sailing experience. From comfortable interiors to stunning facilities, this is a perfect cruise line to enjoy sailing from the UK. Call our Cruise Concierge team on 0808 239 4514 for award-winning customer service and advice on your P&O booking.

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