P&O Cruises from Southampton

Find Out More About P&O Cruises

P&O Cruises is one of the biggest operators of Southampton cruises, sailing to destinations across Europe and the Caribbean. Worldwide cruises from Southampton also visit a wealth of further destinations, so wherever you're looking to travel you'll find something that's right for you.


Refine your search:
Mediterranean
Southampton | La Coruña | Málaga | Cartagena | Barcelona | Cádiz | Southampton
28 Sep 2025
13 Nights
Arvia
Northern Europe
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £107pp
Cruise Only From
Was £899pp
Now: £881 pp
REF: POK520
Mediterranean
Southampton | Cartagena | Cagliari | Katakolon | Corfu | Dubrovnik | Split | Messina | Gibraltar | Southampton
02 Oct 2025
19 Nights
Aurora
Mediterranean
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £219pp
Cruise Only From
Was £2299pp
Now: £2057 pp
REF: POR518
Spain, Portugal and Canary Islands
Southampton | Funchal, Madeira | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Lanzarote | Cádiz | La Coruña | Southampton
03 Oct 2025
14 Nights
Britannia
Atlantic Islands
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £125pp
Cruise Only From
Was £1279pp
Now: £1175 pp
REF: POB524
Spain and Portugal
Southampton | Cherbourg | Leixões | Lisbon | Vigo | Southampton
04 Oct 2025
7 Nights
Ventura
Western Europe
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £76pp
Cruise Only From
Was £729pp
Now: £714 pp
REF: PON525
Mediterranean
Southampton | La Coruña | Málaga | Barcelona | Alicante | Cádiz | Southampton
11 Oct 2025
13 Nights
Arvia
Northern Europe
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £94pp
Cruise Only From
Was £949pp
Now: £881 pp
REF: POK521
Spain, Portugal and Canary Islands
Southampton | Funchal, Madeira | Santa Cruz de La Palma | Santa Cruz de Tenerife | Fuerteventura | Lanzarote | Cádiz | Lisbon | Southampton
11 Oct 2025
14 Nights
Ventura
Atlantic Islands
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £110pp
Cruise Only From
Was £1089pp
Now: £1028 pp
REF: PON526
Portugal And Canary Islands
Southampton | Funchal, Madeira | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton
17 Oct 2025
14 Nights
Britannia
Atlantic Islands
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £105pp
Cruise Only From
Was £1079pp
Now: £979 pp
REF: POB525
Spain and France
Southampton | La Coruña | Gijón | Santander | Cherbourg | Southampton
19 Oct 2025
7 Nights
Arcadia
Northern Europe
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £71pp
Cruise Only From
Was £679pp
Now: £665 pp
REF: POJ516
Norway
Southampton | Åndalsnes | Hammerfest | Alta | Hammerfest | Alta | Tromsø | Tromsø | Haugesund | Southampton
21 Oct 2025
12 Nights
Aurora
Northern Europe
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £108pp
Cruise Only From
Was £1029pp
Now: £1008 pp
REF: POR519
Mini Break At Sea
Southampton | Southampton
23 Oct 2025
2 Nights
Iona
Northern Europe
Departs from the UK
Interest free Monthly Payments from JUST £26pp
Cruise Only From
Was £249pp
Now: £244 pp
REF: POG533N
Caribbean Transatlantic
Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown
24 Oct 2025
14 Nights
Arvia
Caribbean
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £115pp
Fly Cruise From
Was £1129pp
Now: £1077 pp
REF: POK522
Caribbean Transatlantic
Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown | Bridgetown
24 Oct 2025
15 Nights
Arvia
Caribbean
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £125pp
Fly Cruise From
Was £1249pp
Now: £1175 pp
REF: POK522A
Caribbean Transatlantic
Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown | Bridgetown | Martinique | Saint Kitts | Tortola | Sint Maarten | Saint John's
24 Oct 2025
22 Nights
Arvia
Caribbean
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £199pp
Fly Cruise From
Was £1909pp
Now: £1871 pp
REF: POK522B
Spain and France
Southampton | La Coruña | Gijón | Santander | La Rochelle | Southampton
25 Oct 2025
7 Nights
Ventura
Northern Europe
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £71pp
Cruise Only From
Was £679pp
Now: £665 pp
REF: PON527
Spain And France
Southampton | Bilbao | La Coruña | Vigo | Cherbourg | Southampton
25 Oct 2025
7 Nights
Iona
Western Europe
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £82pp
Cruise Only From
Was £779pp
Now: £763 pp
REF: POG534
Belgium
Southampton | Zeebrugge | Southampton
26 Oct 2025
3 Nights
Arcadia
Northern Europe
Departs from the UK
Interest free Monthly Payments from JUST £42pp
Cruise Only From
Was £399pp
Now: £391 pp
REF: POJ517
Mediterranean
Southampton | Tangier | Palermo | Piraeus | Kusadasi | Heraklion (Iraklion), Crete | Valletta | Cádiz | Southampton
29 Oct 2025
19 Nights
Arcadia
Mediterranean
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £167pp
Cruise Only From
Was £1849pp
Now: £1567 pp
REF: POJ518
Caribbean Transatlantic
Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Castries | Bridgetown
31 Oct 2025
14 Nights
Britannia
Caribbean
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £99pp
Fly Cruise From
Was £1109pp
Now: £1038 pp
REF: POB526
Caribbean Transatlantic
Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Castries | Bridgetown | Bridgetown
31 Oct 2025
15 Nights
Britannia
Caribbean
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £109pp
Fly Cruise From
Was £1219pp
Now: £1146 pp
REF: POB526A
Northern European City Escape
Southampton | Rotterdam | Rotterdam | Hamburg | Zeebrugge | Southampton
01 Nov 2025
7 Nights
Iona
Northern Europe
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £49pp
Cruise Only From
Was £549pp
Now: £518 pp
REF: POG535
Portugal And Canary Islands
Southampton | La Coruña | Lisbon | Lanzarote | Santa Cruz de La Palma | Santa Cruz de Tenerife | Santa Cruz de Tenerife | Funchal, Madeira | Southampton
01 Nov 2025
14 Nights
Ventura
Atlantic Islands
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £84pp
Cruise Only From
Was £899pp
Now: £881 pp
REF: PON528
Caribbean
Southampton | Santa Cruz de Tenerife | Sint Maarten | Guadeloupe | Saint Vincent | Castries | Bridgetown | Ponta Delgada, Azores | Southampton
02 Nov 2025
24 Nights
Aurora
Caribbean
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £176pp
Cruise Only From
Was £1929pp
Now: £1861 pp
REF: POR520
Portugal And Canary Islands
Southampton | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Funchal, Madeira | Cádiz | Vigo | La Coruña | Southampton
08 Nov 2025
14 Nights
Iona
Atlantic Islands
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £85pp
Cruise Only From
Was £909pp
Now: £891 pp
REF: POG536
Rotterdam
Southampton | Rotterdam | Rotterdam | Southampton
15 Nov 2025
4 Nights
Ventura
Northern Europe
Departs from the UK
Interest free Monthly Payments from JUST £31pp
Cruise Only From
Was £349pp
Now: £322 pp
REF: PON529
Portugal And Canary Islands
Southampton | La Coruña | Funchal, Madeira | Funchal, Madeira | Santa Cruz de Tenerife | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Southampton
17 Nov 2025
16 Nights
Arcadia
Atlantic Islands
Departs from the UK
Book a Select Fare and receive EXTRA on-board spending money per stateroom
10% off classic drinks package - *on selected sailings
EXTENDED PAY DAY SALE! Save an up to extra £50 per stateroom when you book online - ends Friday!
Interest free Monthly Payments from JUST £111pp
Cruise Only From
Was £1199pp
Now: £1175 pp
REF: POJ519

Prices are subject to change and availability. Prices may vary depending on airport selected. Promotions are only applicable to select cabins grades, please call for details

Find P&O Cruises from Southampton

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P&O Cruises from Southampton are a fantastically convenient way to explore the world, without the need to think about arranging flights. There's no need to worry about what to pack either – as long as your bags can fit into your cabin, you're welcome to bring as much luggage as you like!

Cruising from Southampton offers a variety of benefits, including dedicated parking and transfer facilities with drop-off points right next to the ship terminals. If you're looking for a change from flights and hotel stays, this could be the perfect low-stress holiday.

P&O Cruises ships sailing from Southampton

Each ship in the P&O Cruises fleet sails from Southampton, offering you the widest choice to select from, whether it's a family-friendly cruise or an adults-only sailing.

Destinations you can reach from the UK

Cruise from Southampton with P&O Cruises and you'll find a whole host of destinations just waiting to be explored. Where you can cruise to depends on the duration of your cruise:

  • Mini cruises - cruise for two to five nights and you can reach interesting European ports such as Guernsey, Amsterdam, Cherbourg and Bruges. 
  • 7-night cruises - cruise for a week and you can explore the Norwegian Fjords, Holland, France and Belgium or head south to Spain and Portugal
  • 14-night cruises - in two weeks you can cruise to Italy and back, explore the Baltics or get some winter sun in the Canary Islands
  • Long duration cruises - head transatlantic to the USA and Canada, cruise the Caribbean or push the boat out with a world cruise

Book your P&O cruise from the UK

Look ahead to sailing with P&O Cruises from Southampton and enjoy a quintessentially British sailing experience. From comfortable interiors to stunning facilities, this is a perfect cruise line to enjoy sailing from the UK. Call our Cruise Concierge team on 0808 239 4514 for award-winning customer service and advice on your P&O booking.

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