This year, Royal Caribbean will have the most cruise ships in the Mediterranean so there really is no better time to explore everything it has to offer. With a number of ships exploring the Mediterranean in 2022, including brand new ship; Wonder of the Seas, there is so much do and see with Royal Caribbean both at sea and on land.

Each ship is unique and explore some of the most incredible destinations you will find in the Mediterranean – you can choose your ship and itinerary based on your needs and requirements, with many itineraries being served by multiple ships. To help you on your way, we have pulled together some of our favourite Royal Caribbean Mediterranean itineraries.

The Western Mediterranean on-board Wonder of the Seas

Wonder of the Seas

What better way to start than to take a look at the new Wonder of the Seas? Launching in March 2022, the new Royal Caribbean ship is like no other – with a re-imagined pool deck, new cabins and incredible entertainment you can be sure that a cruise on Wonder of the Seas will be an experience to remember.

On this trip, you can explore everything that major cities and culture spots have to offer in the Mediterranean. In 7 nights, you will visit Barcelona, Mallorca, Marseille, La Spezia, Rome and Naples before returning to Barcelona. This cruise sails from Barcelona so you can even spend a few nights in this great city before or after your cruise exploring and experiencing everything it has to offer.

The Greek Isles on-board Brilliance of the Seas


Brilliance of the Seas is part of Royal Caribbean’s Radiance class fleet – it offers innovative design and modern facilities to make it one of the most comfortable ships available. You will find expansive open spaces on-board and glass interiors so you can experience the ocean from anywhere on the ship.

This trip starts in Italy, calling at Montenegro, before departing for the Greek Isles where you will spend 7 nights visiting Corfu, Athens, Mykonos and Argostoli before returning to Italy. On this trip you can experience everything Greece has to offer from history to culture and cuisine. It is the perfect trip if you want to soak up a little bit of everything Greece has to offer.

Spanish Transatlantic on-board Odyssey of the Seas

Odyssey of the Seas

Odyssey of the Seas is part of Royal Caribbean’s Quantum Ultra Class and is the sister to Spectrum of the Seas. You will find amenities on-board such as the North Star Observation pod, robot bartenders and indoor skydiving!

On the Spanish Transatlantic sailing, you will begin in Florida where you can spend a few days if you wish soaking up some sun before setting sail to visit the ports of Funchal, Malaga, Cartagena, Florence and finally finishing up in Rome where you also have the chance to stay a few more days to explore the culture.

Mediterranean Greek isles on-board Vision of the Seas


Vision of the Seas is a much more intimate journey. This mid-size ship has a smaller capacity so can slip into smaller ports that other ships can’t reach. However, this does not mean it lacks in activities. You will still find plenty of bars, restaurants and lounges as well as Royal Caribbean’s signature rock climbing wall!

On this exciting Royal Caribbean Mediterranean cruise you will spend 12 nights exploring the Mediterranean and Greek Isles. Starting and finishing in Barcelona you will visit the ports of Cannes, Florence/Pisa, Rome, Crete, Mykonos, Athens, Kusadasi and Santorini for a true once in a lifetime cruising experience.

Greek & Adriatic on Rhapsody of the Seas

Rhapsody of the Seas

Part of the Vision Class, again Rhapsody of the Seas is slightly smaller in size and much more intimate – offering trips to some of the lesser visited ports across the Mediterranean. This ship has a sleek design and a lot of glass features, including skylights, canopies and windows throughout. Despite the smaller size you will still have access to several restaurants, bars and theatres among other leisure facilities.

On this 7 night Greek & Adriatic cruise you will begin your journey in Athens, where you can add a stay at the Melia hotel if you wish before sailing onto the ports of Mykonos, Crete, Zakynthos, Montenegro, Split and then finish your journey in Ravenna, Italy.

Mediterranean Beach & Cities on-board Anthem of the Seas

Anthem Ifly

The second of Royal Caribbean’s Quantum Class ships in the Mediterranean is Anthem of the Seas. There are a whole host of first-class experiences on-board this ship including shows and live music – with the RipCord skydiving simulator on-board! There is plenty of innovation on this ship that you do not want to miss!

This ship sails from Southampton, UK, before it spends 14 nights visiting the ports of Seville, Malaga, Valencia, Mallorca, Barcelona, Ibiza and Lisbon and then returning to the UK. You will get to experience everything on this trip with a true mix of beach and cities to explore and relax – it has it all.

With so many exciting itineraries and ships to choose from, be sure to experience it all with Royal Caribbean Mediterranean cruises! If you’re not sure which ship or sailing is right for you our friendly expert cruise concierge can help you put together the best package, just get in touch.

View all Royal Caribbean’s Mediterranean sailings here!

Charlotte Richards

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