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P & O Cruises > P&O Cruises from Southampton
Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price.
P&O Cruises P&O Cruise Deals Cruises from Southampton P&O Cruises 2026 P&O Cruises 2027 P&O Cruises 2028
Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.
DEPARTS FROM UK
Southampton | Hamburg | Zeebrugge | Southampton
DEPARTS FROM UK
Southampton | Funchal | Sint Maarten | Saint John's | Dominica | Saint Vincent | Saint George's | Port-of-Spain | Bonaire | Curaçao | Cartagena | Colón | Puerto Limón | Roatán Island | Costa Maya | Grand Cayman | Cozumel | Progreso | Galveston | New Orleans | Miami | Port Canaveral | Freeport | Grand Turk Island | Amber Cove | Ocho Rios | Falmouth | Tortola | Saint Kitts | Guadeloupe | Martinique | Castries | Scarborough | Bridgetown | Praia da Vitória | Southampton
DEPARTS FROM UK
Southampton | Santa Cruz de Tenerife | Saint Kitts | Bridgetown | Saint George's | Castries | Sint Maarten | Saint John's | Las Palmas de Gran Canaria | La Coruña | Southampton
DEPARTS FROM UK
Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton
Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney | Newcastle | Brisbane
Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco
DEPARTS FROM UK
Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney | Newcastle | Brisbane | Cairns | Alotau | Manila | Hong Kong | Singapore | Port Klang | Georgetown | Colombo | Mauritius | Saint-Denis de la Réunion | Durban | Gqeberha (ex Port Elizabeth) | Cape Town | Walvis Bay | Sao Vicente Island | Santa Cruz de Tenerife | Southampton
Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney
Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney | Newcastle | Brisbane | Cairns | Alotau | Manila | Hong Kong
DEPARTS FROM UK
Southampton | Cherbourg | Vigo | La Coruña | Getxo | Southampton
Interest free Monthly Payments from JUST £134pp
DEPARTS FROM UK
Southampton | Funchal | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton
DEPARTS FROM UK
Southampton | Zeebrugge | Rotterdam | Cherbourg | Southampton
Interest free Monthly Payments from JUST £96pp
DEPARTS FROM UK
Southampton | Amsterdam | Southampton
Interest free Monthly Payments from JUST £84pp
DEPARTS FROM UK
Southampton | Funchal | Santa Cruz de La Palma | Lanzarote | Casablanca | Tangier | Cádiz | La Coruña | Southampton
DEPARTS FROM UK
Southampton | Rotterdam | Zeebrugge | Hamburg | Southampton
Interest free Monthly Payments from JUST £120pp
DEPARTS FROM UK
Southampton | Rotterdam | Zeebrugge | Hamburg | Southampton
Interest free Monthly Payments from JUST £104pp
DEPARTS FROM UK
Southampton | Cartagena | La Goulette | Valletta | Piraeus | Naples | Civitavecchia | Barcelona | Alicante | Cádiz | Lisbon | Southampton
DEPARTS FROM UK
Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton
Interest free Monthly Payments from JUST £195pp
DEPARTS FROM UK
Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Vigo | La Coruña | Southampton
Interest free Monthly Payments from JUST £176pp
DEPARTS FROM UK
Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Southampton
Interest free Monthly Payments from JUST £169pp
DEPARTS FROM UK
Southampton | Ålesund | Bodø | Narvik | Tromsø | Haugesund | Southampton
DEPARTS FROM UK
Southampton | Hamburg | Rotterdam | Zeebrugge | Southampton
Interest free Monthly Payments from JUST £107pp
DEPARTS FROM UK
Southampton | Haugesund | Olden | Ålesund | Stavanger | Southampton
Interest free Monthly Payments from JUST £126pp
DEPARTS FROM UK
Southampton | Zeebrugge | Southampton
Interest free Monthly Payments from JUST £55pp
DEPARTS FROM UK
Southampton | Cádiz | Heraklion (Iraklion) | Alexandria | La Goulette | Cartagena | Tangier | Ferrol | Southampton
Interest free Monthly Payments from JUST £244pp
DEPARTS FROM UK
Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton | Haugesund | Ålesund | Skjolden | Stavanger | Southampton
Interest free Monthly Payments from JUST £218pp
DEPARTS FROM UK
Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton
Interest free Monthly Payments from JUST £111pp
DEPARTS FROM UK
Southampton | Stavanger | Olden | Ålesund | Haugesund | Southampton
Interest free Monthly Payments from JUST £118pp
DEPARTS FROM UK
Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton
Interest free Monthly Payments from JUST £159pp
DEPARTS FROM UK
Southampton | Haugesund | Olden | Ålesund | Stavanger | Southampton
Interest free Monthly Payments from JUST £113pp
Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.
Southampton is home to the most popular departure port in the UK and is another port for you to explore before or after your cruise. Cruising from Southampton allows you to avoid the fees and hassle of airports to get an early start on your cruises from the UK . P&O cruises from Southampton are perfect for many cruisers since all you have to do is drive down to the port and board your cruise. Whether you are looking for the best cruises for families or venturing out as a couple with our adult only cruises, departing aboard a P&O Cruises from Southampton makes for a more convenient and affordable holiday. Sail hassle free by opting for our all-inclusive cruises.
P&O Cruises from Southampton sails to many amazing destinations. You can sail closer to home on an Europe Cruise and explore popular holiday countries like Spain, France and Portugal or you can see the beauty of the Northern lights on a Norwegian Fjords cruise. If you are looking for warmer climates to escape the cold, the Caribbean is calling with our P&O cruises to the Caribbean, South American Cruises, Mediterranean Cruises, Canaries Islands Cruises and more. P&O cruises from Southampton offers World Cruises where you can explore multiple countries and learn more about the world as you traverse through the continents. Whether you are looking to sail on short break cruises or venturing out with our long duration cruises, you will find P&O cruises from Southampton that will tick all your boxes.
Browse through our wide range of P&O cruises from Southampton with amazing itineraries. Looking to sail a few days or 3 months in the future? Our last minute cruise deals on 2026 cruises will allow you to save more on your cruise holiday. Take advantage of our early booking discounts and save your place onboard with our low deposits when you are sailing on 2027 Cruises or 2028 Cruises. Whenever you are looking to sail, we have exclusive cruise deals on P&O cruises from Southampton.
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