P&O Cruises to the Mediterranean

Showing 30 out of 561 cruises
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Fly Cruise From:
Was £639pp Now: £619pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife

  • 04 Dec 2026
  • 7 Nights
  • Azura
  • Mediterranean
  • 04 Dec 2026
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £639pp Now: £619pp
View cruise
REF: POA648
Fly Cruise From:
Was £1119pp Now: £1085pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 04 Dec 2026
  • 14 Nights
  • Azura
  • Mediterranean
  • 04 Dec 2026
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1119pp Now: £1085pp
View cruise
REF: POA648A
Fly Cruise From:
Was £579pp Now: £561pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife

  • 05 Dec 2026
  • 7 Nights
  • Azura
  • Mediterranean
  • 05 Dec 2026
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £579pp Now: £561pp
View cruise
REF: POA648B
Fly Cruise From:
Was £1049pp Now: £1017pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 05 Dec 2026
  • 14 Nights
  • Azura
  • Mediterranean
  • 05 Dec 2026
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1049pp Now: £1017pp
View cruise
REF: POA648C

DEPARTS FROM UK

Cruise From:
Was £879pp Now: £852pp

Spain Portugal and Canary Islands

Southampton | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 05 Dec 2026
  • 14 Nights
  • Iona
  • Mediterranean
  • 05 Dec 2026
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £879pp Now: £852pp
View cruise
REF: POG639
Fly Cruise From:
Was £579pp Now: £561pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 11 Dec 2026
  • 7 Nights
  • Azura
  • Mediterranean
  • 11 Dec 2026
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £579pp Now: £561pp
View cruise
REF: POA649
Fly Cruise From:
Was £1469pp Now: £1424pp

Spain and Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife | Fuerteventura | Funchal | Lisbon | Cádiz | Tangier | Málaga

  • 11 Dec 2026
  • 17 Nights
  • Azura
  • Mediterranean
  • 11 Dec 2026
  • 17 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1469pp Now: £1424pp
View cruise
REF: POA649A
Fly Cruise From:
Was £579pp Now: £561pp

Spain and Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 12 Dec 2026
  • 7 Nights
  • Azura
  • Mediterranean
  • 12 Dec 2026
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £579pp Now: £561pp
View cruise
REF: POA649B
Fly Cruise From:
Was £1399pp Now: £1357pp

Spain and Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife | Fuerteventura | Funchal | Lisbon | Cádiz | Tangier | Málaga

  • 12 Dec 2026
  • 17 Nights
  • Azura
  • Mediterranean
  • 12 Dec 2026
  • 17 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1399pp Now: £1357pp
View cruise
REF: POA649C
Fly Cruise From:
Was £1399pp Now: £1357pp

Spain and Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Fuerteventura | Funchal | Lisbon | Cádiz | Tangier | Málaga

  • 18 Dec 2026
  • 10 Nights
  • Azura
  • Mediterranean
  • 18 Dec 2026
  • 10 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1399pp Now: £1357pp
View cruise
REF: POA650
Fly Cruise From:
Was £1999pp Now: £1939pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Fuerteventura | Funchal | Lisbon | Cádiz | Tangier | Málaga | Barcelona | Cartagena | Gibraltar | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife

  • 18 Dec 2026
  • 21 Nights
  • Azura
  • Mediterranean
  • 18 Dec 2026
  • 21 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1999pp Now: £1939pp
View cruise
REF: POA650A
Fly Cruise From:
Was £1349pp Now: £1299pp

Spain and Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Fuerteventura | Funchal | Lisbon | Cádiz | Tangier | Málaga

  • 19 Dec 2026
  • 10 Nights
  • Azura
  • Mediterranean
  • 19 Dec 2026
  • 10 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1349pp Now: £1299pp
View cruise
REF: POA650B
Fly Cruise From:
Was £1989pp Now: £1929pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Fuerteventura | Funchal | Lisbon | Cádiz | Tangier | Málaga | Barcelona | Cartagena | Gibraltar | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife

  • 19 Dec 2026
  • 21 Nights
  • Azura
  • Mediterranean
  • 19 Dec 2026
  • 21 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1989pp Now: £1929pp
View cruise
REF: POA650C

DEPARTS FROM UK

Cruise From:
Was £1819pp Now: £1764pp

Spain Portugal and Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Fuerteventura | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | La Coruña | Southampton

  • 19 Dec 2026
  • 16 Nights
  • Iona
  • Mediterranean
  • 19 Dec 2026
  • 16 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1819pp Now: £1764pp
View cruise
REF: POG640

DEPARTS FROM UK

Cruise From:
Was £1949pp Now: £1890pp

Christmas Sailing! Spain Portugal and Canary Islands

Southampton | Vigo | Lanzarote | Fuerteventura | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal | Lisbon | Southampton

  • 21 Dec 2026
  • 16 Nights
  • Arcadia
  • Mediterranean
  • 21 Dec 2026
  • 16 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1949pp Now: £1890pp
View cruise
REF: POJ619

DEPARTS FROM UK

Cruise From:
Was £1649pp Now: £1599pp

Spain Portugal and Canary Islands

Southampton | La Coruña | Santa Cruz de Tenerife | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Lanzarote | Funchal | Southampton

  • 21 Dec 2026
  • 14 Nights
  • Ventura
  • Mediterranean
  • 21 Dec 2026
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1649pp Now: £1599pp
View cruise
REF: PON635
Fly Cruise From:
Was £1159pp Now: £1124pp

Spain and Canary Islands Fly-Cruise

Málaga | Barcelona | Cartagena | Gibraltar | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife

  • 28 Dec 2026
  • 11 Nights
  • Azura
  • Mediterranean
  • 28 Dec 2026
  • 11 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1159pp Now: £1124pp
View cruise
REF: POA651
Fly Cruise From:
Was £1399pp Now: £1357pp

Spain and Canary Islands Fly-Cruise

Málaga | Barcelona | Cartagena | Gibraltar | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 28 Dec 2026
  • 18 Nights
  • Azura
  • Mediterranean
  • 28 Dec 2026
  • 18 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1399pp Now: £1357pp
View cruise
REF: POA651A
Fly Cruise From:
Was £1049pp Now: £1017pp

Spain and Canary Islands Fly-Cruise

Málaga | Barcelona | Cartagena | Gibraltar | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife

  • 29 Dec 2026
  • 11 Nights
  • Azura
  • Mediterranean
  • 29 Dec 2026
  • 11 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1049pp Now: £1017pp
View cruise
REF: POA651B
Fly Cruise From:
Was £1379pp Now: £1337pp

Sail over New Year! Spain and Canary Islands Fly-Cruise

Málaga | Barcelona | Cartagena | Gibraltar | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 29 Dec 2026
  • 18 Nights
  • Azura
  • Mediterranean
  • 29 Dec 2026
  • 18 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1379pp Now: £1337pp
View cruise
REF: POA651C

DEPARTS FROM UK

Cruise From:
Was £7999pp Now: £7759pp

America and Caribbean Discovery

Southampton | Funchal | Sint Maarten | Saint John's | Dominica | Saint Vincent | Saint George's | Port-of-Spain | Bonaire | Curaçao | Cartagena | Colón | Puerto Limón | Roatán Island | Costa Maya | Grand Cayman | Cozumel | Progreso | Galveston | New Orleans | Miami | Port Canaveral | Freeport | Grand Turk Island | Amber Cove | Ocho Rios | Falmouth | Tortola | Saint Kitts | Guadeloupe | Martinique | Castries | Scarborough | Bridgetown | Praia da Vitória | Southampton

  • 03 Jan 2027
  • 75 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £7999pp Now: £7759pp
View cruise
REF: POR701

DEPARTS FROM UK

Cruise From:
Was £2699pp Now: £2618pp

Caribbean Discovery

Southampton | Santa Cruz de Tenerife | Saint Kitts | Bridgetown | Saint George's | Castries | Sint Maarten | Saint John's | Las Palmas de Gran Canaria | La Coruña | Southampton

  • 04 Jan 2027
  • 35 Nights
  • Iona
  • Caribbean
  • 04 Jan 2027
  • 35 Nights
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2699pp Now: £2618pp
View cruise
REF: POG701

DEPARTS FROM UK

Cruise From:
Was £949pp Now: £920pp

PRICE DROP! Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 04 Jan 2027
  • 14 Nights
  • Ventura
  • Mediterranean
  • 04 Jan 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £949pp Now: £920pp
View cruise
REF: PON701N
Fly Cruise From:
Was £6619pp Now: £6420pp

World Cruise Segment - Southampton to San Francisco

Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco

  • 06 Jan 2027
  • 22 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £6619pp Now: £6420pp
View cruise
REF: POJ701SOUSFO

DEPARTS FROM UK

Cruise From:
Was £11419pp Now: £11076pp

Western Circumnavigation

Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney | Newcastle | Brisbane | Cairns | Alotau | Manila | Hong Kong | Singapore | Port Klang | Georgetown | Colombo | Mauritius | Saint-Denis de la Réunion | Durban | Gqeberha (ex Port Elizabeth) | Cape Town | Walvis Bay | Sao Vicente Island | Santa Cruz de Tenerife | Southampton

  • 06 Jan 2027
  • 107 Nights
  • Arcadia
  • Asia & Indian Ocean
  • 06 Jan 2027
  • 107 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £11419pp Now: £11076pp
View cruise
REF: POJ701
Fly Cruise From:
Was £5999pp Now: £5819pp

World Cruise Segment - Southampton to Sydney

Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney

  • 06 Jan 2027
  • 43 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £5999pp Now: £5819pp
View cruise
REF: POJ701SOUSYD
Fly Cruise From:
Was £5649pp Now: £5479pp

Epic World Explorer

Southampton | Funchal | Bridgetown | Curaçao | Manzanillo | San Francisco | Hilo | Honolulu | Apia | Suva | Port Vila | Sydney | Newcastle | Brisbane | Cairns | Alotau | Manila | Hong Kong

  • 06 Jan 2027
  • 63 Nights
  • Arcadia
  • Asia & Indian Ocean
  • 06 Jan 2027
  • 63 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £5649pp Now: £5479pp
View cruise
REF: POJ701SOUHKG
Fly Cruise From:
Was £669pp Now: £648pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 08 Jan 2027
  • 7 Nights
  • Azura
  • Mediterranean
  • 08 Jan 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £669pp Now: £648pp
View cruise
REF: POA701
Fly Cruise From:
Was £1149pp Now: £1114pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife | Funchal | Las Palmas de Gran Canaria | Lanzarote | Santa Cruz de Tenerife

  • 08 Jan 2027
  • 14 Nights
  • Azura
  • Mediterranean
  • 08 Jan 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £1149pp Now: £1114pp
View cruise
REF: POA701A
Fly Cruise From:
Was £609pp Now: £590pp

Canary Islands Fly-Cruise

Santa Cruz de Tenerife | Funchal | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife

  • 09 Jan 2027
  • 7 Nights
  • Azura
  • Mediterranean
  • 09 Jan 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £609pp Now: £590pp
View cruise
REF: POA701B

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.


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