P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

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Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 426 cruises
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DEPARTS FROM UK

Cruise From:
Was £3599pp Now: £3491pp

Central Mediterranean Discovery

Southampton | Cartagena | La Goulette | Palermo | Sarandë | Dubrovnik | Split | Zadar | Korčula | Valletta | Cádiz | Southampton

  • 04 Oct 2027
  • 21 Nights
  • Arcadia
  • Mediterranean
  • 04 Oct 2027
  • 21 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £3599pp Now: £3491pp
View cruise
REF: POJ714

DEPARTS FROM UK

Cruise From:
Was £619pp Now: £600pp

Spain And France

Southampton | Gijón | La Coruña | Vigo | Cherbourg | Southampton

  • 08 Oct 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £52pp

Cruise From:
Was £619pp Now: £600pp
View cruise
REF: POB726

DEPARTS FROM UK

Cruise From:
Was £1209pp Now: £1172pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 09 Oct 2027
  • 14 Nights
  • Ventura
  • Mediterranean
  • 09 Oct 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £100pp

Cruise From:
Was £1209pp Now: £1172pp
View cruise
REF: PON726

DEPARTS FROM UK

Cruise From:
Was £1399pp Now: £1357pp

Norwegian Fjords

Southampton | Haugesund | Olden | Molde | Bodø | Ålesund | Skjolden | Stavanger | Southampton

  • 11 Oct 2027
  • 14 Nights
  • Aurora
  • Scandinavia
  • 11 Oct 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £115pp

Cruise From:
Was £1399pp Now: £1357pp
View cruise
REF: POR719

DEPARTS FROM UK

Cruise From:
Was £1149pp Now: £1114pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Ferrol | Southampton

  • 15 Oct 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £93pp

Cruise From:
Was £1149pp Now: £1114pp
View cruise
REF: POB727

DEPARTS FROM UK

Cruise From:
Was £629pp Now: £610pp

Spain And France

Southampton | Getxo | La Coruña | Vigo | Cherbourg | Southampton

  • 15 Oct 2027
  • 7 Nights
  • Arvia
  • Mediterranean
  • 15 Oct 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £51pp

Cruise From:
Was £629pp Now: £610pp
View cruise
REF: POK723

DEPARTS FROM UK

Cruise From:
Was £729pp Now: £707pp

Northern European City Escape

Southampton | Zeebrugge | Rotterdam | Hamburg | Southampton

  • 16 Oct 2027
  • 7 Nights
  • Iona
  • United Kingdom
  • 16 Oct 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £59pp

Cruise From:
Was £729pp Now: £707pp
View cruise
REF: POG735
Fly Cruise From:
Was £1179pp Now: £1143pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown

  • 22 Oct 2027
  • 14 Nights
  • Arvia
  • Caribbean
  • 22 Oct 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £94pp

Fly Cruise From:
Was £1179pp Now: £1143pp
View cruise
REF: POK724
Fly Cruise From:
Was £1399pp Now: £1357pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown

  • 22 Oct 2027
  • 15 Nights
  • Arvia
  • Caribbean
  • 22 Oct 2027
  • 15 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £111pp

Fly Cruise From:
Was £1399pp Now: £1357pp
View cruise
REF: POK724A
Fly Cruise From:
Was £1629pp Now: £1580pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown | Saint Kitts

  • 22 Oct 2027
  • 17 Nights
  • Arvia
  • Caribbean
  • 22 Oct 2027
  • 17 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £129pp

Fly Cruise From:
Was £1629pp Now: £1580pp
View cruise
REF: POK724B
Fly Cruise From:
Was £2329pp Now: £2259pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Saint Kitts | Castries | Bridgetown | Saint Kitts | Tortola | Sint Maarten | Dominica | Saint John's

  • 22 Oct 2027
  • 22 Nights
  • Arvia
  • Caribbean
  • 22 Oct 2027
  • 22 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £185pp

Fly Cruise From:
Was £2329pp Now: £2259pp
View cruise
REF: POK724C

DEPARTS FROM UK

Cruise From:
Was £699pp Now: £678pp

PRICE DROP! Spain And France

Southampton | Cherbourg | Getxo | La Coruña | Vigo | Southampton

  • 23 Oct 2027
  • 7 Nights
  • Iona
  • Mediterranean
  • 23 Oct 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £56pp

Cruise From:
Was £699pp Now: £678pp
View cruise
REF: POG736

DEPARTS FROM UK

Cruise From:
Was £749pp Now: £726pp

PRICE DROP! Spain And Portugal

Southampton | Vigo | Lisbon | Leixões | La Coruña | Southampton

  • 23 Oct 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £60pp

Cruise From:
Was £749pp Now: £726pp
View cruise
REF: PON727

DEPARTS FROM UK

Cruise From:
Was £2459pp Now: £2385pp

Spain Portugal And Morocco

Southampton | Funchal | Agadir | Casablanca | Tangier | Motril | Lisbon | Southampton

  • 25 Oct 2027
  • 14 Nights
  • Arcadia
  • Mediterranean
  • 25 Oct 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £193pp

Cruise From:
Was £2459pp Now: £2385pp
View cruise
REF: POJ715

DEPARTS FROM UK

Cruise From:
Was £2749pp Now: £2666pp

Spain Portugal Cape Verde And Morocco

Southampton | La Coruña | Vigo | Ponta Delgada | Praia da Vitória | Funchal | Praia | Sao Vicente Island | Lanzarote | Agadir | Casablanca | Cádiz | Southampton

  • 25 Oct 2027
  • 23 Nights
  • Aurora
  • Mediterranean
  • 25 Oct 2027
  • 23 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £216pp

Cruise From:
Was £2749pp Now: £2666pp
View cruise
REF: POR720N

DEPARTS FROM UK

Cruise From:
Was £1349pp Now: £1299pp

Spain Madeira And Canary Islands

Southampton | Lanzarote | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal | Gibraltar | Cádiz | Southampton

  • 29 Oct 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £104pp

Cruise From:
Was £1349pp Now: £1299pp
View cruise
REF: POB728
Fly Cruise From:
Was £1279pp Now: £1240pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown

  • 30 Oct 2027
  • 14 Nights
  • Iona
  • Caribbean
  • 30 Oct 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £99pp

Fly Cruise From:
Was £1279pp Now: £1240pp
View cruise
REF: POG737A
Fly Cruise From:
Was £1599pp Now: £1551pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown | Saint Kitts

  • 30 Oct 2027
  • 16 Nights
  • Iona
  • Caribbean
  • 30 Oct 2027
  • 16 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £124pp

Fly Cruise From:
Was £1599pp Now: £1551pp
View cruise
REF: POG737B
Fly Cruise From:
Was £2049pp Now: £1987pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown | Saint Kitts | Tortola | Sint Maarten | Martinique | Saint John's

  • 30 Oct 2027
  • 21 Nights
  • Iona
  • Caribbean
  • 30 Oct 2027
  • 21 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £159pp

Fly Cruise From:
Was £2049pp Now: £1987pp
View cruise
REF: POG737C
Fly Cruise From:
Was £1079pp Now: £1046pp

Caribbean Transatlantic

Southampton | Santa Cruz de Tenerife | Sint Maarten | Dominica | Bridgetown

  • 30 Oct 2027
  • 13 Nights
  • Iona
  • Caribbean
  • 30 Oct 2027
  • 13 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £84pp

Fly Cruise From:
Was £1079pp Now: £1046pp
View cruise
REF: POG737N

DEPARTS FROM UK

Cruise From:
Was £599pp Now: £581pp

Spain

Southampton | Vigo | La Coruña | Gijón | Getxo | Southampton

  • 30 Oct 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £47pp

Cruise From:
Was £599pp Now: £581pp
View cruise
REF: PON728

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

Spain And Canary Islands

Southampton | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Fuerteventura | Cádiz | Vigo | La Coruña | Southampton

  • 06 Nov 2027
  • 14 Nights
  • Ventura
  • Mediterranean
  • 06 Nov 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £76pp

Cruise From:
Was £999pp Now: £969pp
View cruise
REF: PON729

DEPARTS FROM UK

Cruise From:
Was £979pp Now: £949pp

PRICE DROP! Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Southampton

  • 08 Nov 2027
  • 12 Nights
  • Arcadia
  • Mediterranean
  • 08 Nov 2027
  • 12 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £74pp

Cruise From:
Was £979pp Now: £949pp
View cruise
REF: POJ716

DEPARTS FROM UK

Cruise From:
Was £479pp Now: £464pp

Belgium And Netherlands

Southampton | Hamburg | Zeebrugge | Southampton

  • 12 Nov 2027
  • 5 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £36pp

Cruise From:
Was £479pp Now: £464pp
View cruise
REF: POB729

DEPARTS FROM UK

Cruise From:
Was £949pp Now: £920pp

PRICE DROP! Spain Madeira And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Cádiz | La Coruña | Southampton

  • 17 Nov 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £70pp

Cruise From:
Was £949pp Now: £920pp
View cruise
REF: POB730

DEPARTS FROM UK

Cruise From:
Was £1729pp Now: £1677pp

PRICE DROP! Norway

Southampton | Åndalsnes | Hammerfest | Alta | Tromsø | Haugesund | Southampton

  • 17 Nov 2027
  • 12 Nights
  • Aurora
  • Scandinavia
  • 17 Nov 2027
  • 12 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £127pp

Cruise From:
Was £1729pp Now: £1677pp
View cruise
REF: POR721

DEPARTS FROM UK

Cruise From:
Was £1399pp Now: £1357pp

Eastern Mediterranean Discovery

Southampton | Málaga | Palermo | Piraeus | Kusadasi | Rhodes | Heraklion (Iraklion) | Gibraltar | Southampton

  • 20 Nov 2027
  • 19 Nights
  • Arcadia
  • Mediterranean
  • 20 Nov 2027
  • 19 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £102pp

Cruise From:
Was £1399pp Now: £1357pp
View cruise
REF: POJ717

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

PRICE DROP! Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Fuerteventura | Cádiz | Lisbon | Southampton

  • 20 Nov 2027
  • 14 Nights
  • Ventura
  • Mediterranean
  • 20 Nov 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £73pp

Cruise From:
Was £999pp Now: £969pp
View cruise
REF: PON730

DEPARTS FROM UK

Cruise From:
Was £1399pp Now: £1357pp

PRICE DROP! Azores Portugal And Canary Islands

Southampton | Lisbon | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal | Ponta Delgada | Praia da Vitória | Southampton

  • 29 Nov 2027
  • 16 Nights
  • Aurora
  • Mediterranean
  • 29 Nov 2027
  • 16 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £100pp

Cruise From:
Was £1399pp Now: £1357pp
View cruise
REF: POR722

DEPARTS FROM UK

Cruise From:
Was £549pp Now: £532pp

PRICE DROP! Northern European City Escape

Southampton | Le Havre | Hamburg | Southampton

  • 01 Dec 2027
  • 6 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - ends 3rd August
Up to £400 FREE to spend on board when you book a Select Fare
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £39pp

Cruise From:
Was £549pp Now: £532pp
View cruise
REF: POB731

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Why Choose P&O Cruises From The UK

Southampton is home to the most popular departure port in the UK and is another port for you to explore before or after your cruise. Cruising from Southampton allows you to avoid the fees and hassle of airports to get an early start on your cruises from the UK . P&O cruises from Southampton are perfect for many cruisers since all you have to do is drive down to the port and board your cruise. Whether you are looking for the best cruises for families or venturing out as a couple with our adult only cruises, departing aboard a P&O Cruises from Southampton makes for a more convenient and affordable holiday. Sail hassle free by opting for our all-inclusive cruises. 

P&O Cruises from Southampton destinations 

P&O Cruises from Southampton sails to many amazing destinations. You can sail closer to home on an Europe Cruise and explore popular holiday countries like Spain, France and Portugal or you can see the beauty of the Northern lights on a Norwegian Fjords cruise. If you are looking for warmer climates to escape the cold, the Caribbean is calling with our P&O cruises to the Caribbean, South American Cruises, Mediterranean Cruises, Canaries Islands Cruises and more. P&O cruises from Southampton offers World Cruises where you can explore multiple countries and learn more about the world as you traverse through the continents. Whether you are looking to sail on short break cruises or venturing out with our long duration cruises, you will find P&O cruises from Southampton that will tick all your boxes. 

Book Your P&O Cruises From Southampton

Browse through our wide range of P&O cruises from Southampton with amazing itineraries. Looking to sail a few days or 3 months in the future? Our last minute cruise deals on 2026 cruises will allow you to save more on your cruise holiday. Take advantage of our early booking discounts and save your place onboard with our low deposits when you are sailing on 2027 Cruises or 2028 Cruises. Whenever you are looking to sail, we have exclusive cruise deals on P&O cruises from Southampton.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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