P&O Cruises from Southampton

P & O Cruises > P&O Cruises from Southampton

Set sail onboard P&O Cruises from Southampton to a wide range of cruise destinations with specially curated handpicked deals to make sure you are getting the best price possible. Explore the world any time of the year with our summer cruises or winter cruises onboard P&O Cruises state-of-the-art ships. Enjoy fantastic dining options, entertainment and relaxing centres as you sail through different ports of call. Find P&O cruise deals on your P&O Cruises from Southampton sailing and book now for a fraction of the price. 

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Looking for the best cruise deals on P&O cruises from Southampton? Book your cruise deal online or contact us and our expert cruise concierges will help you find the perfect itinerary and best offer on your P&O cruises from Southampton.

Showing 30 out of 428 cruises
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DEPARTS FROM UK

Cruise From:
Was £1399pp Now: £1357pp

PRICE DROP! Azores Portugal And Canary Islands

Southampton | Lisbon | Las Palmas de Gran Canaria | Santa Cruz de Tenerife | Santa Cruz de La Palma | Funchal | Ponta Delgada | Praia da Vitória | Southampton

  • 29 Nov 2027
  • 16 Nights
  • Aurora
  • Mediterranean
  • 29 Nov 2027
  • 16 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £99pp

Cruise From:
Was £1399pp Now: £1357pp
View cruise
REF: POR722

DEPARTS FROM UK

Cruise From:
Was £549pp Now: £532pp

PRICE DROP! Northern European City Escape

Southampton | Le Havre | Hamburg | Southampton

  • 01 Dec 2027
  • 6 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £39pp

Cruise From:
Was £549pp Now: £532pp
View cruise
REF: POB731

DEPARTS FROM UK

Cruise From:
Was £1049pp Now: £1017pp

PRICE DROP! Northern Europe And Scandinavia

Southampton | Copenhagen | Oslo | Skagen | Southampton

  • 04 Dec 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £74pp

Cruise From:
Was £1049pp Now: £1017pp
View cruise
REF: PON731

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

PRICE DROP! Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 07 Dec 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £70pp

Cruise From:
Was £999pp Now: £969pp
View cruise
REF: POB732

DEPARTS FROM UK

Cruise From:
Was £1149pp Now: £1114pp

PRICE DROP! Spain And Morocco

Southampton | Agadir | Casablanca | Tangier | Málaga | Cádiz | Southampton

  • 09 Dec 2027
  • 12 Nights
  • Arcadia
  • Mediterranean
  • 09 Dec 2027
  • 12 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £80pp

Cruise From:
Was £1149pp Now: £1114pp
View cruise
REF: POJ718

DEPARTS FROM UK

Cruise From:
Was £499pp Now: £484pp

Belgium And Netherlands

Southampton | Zeebrugge | Amsterdam | Southampton

  • 11 Dec 2027
  • 5 Nights
  • Ventura
  • United Kingdom
  • 11 Dec 2027
  • 5 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £35pp

Cruise From:
Was £499pp Now: £484pp
View cruise
REF: PON732

DEPARTS FROM UK

Cruise From:
Was £1349pp Now: £1299pp

PRICE DROP! Christmas Scandinavian Escape

Southampton | Copenhagen | Gdynia | Oslo | Hamburg | Zeebrugge | Southampton

  • 15 Dec 2027
  • 14 Nights
  • Aurora
  • Scandinavia
  • 15 Dec 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £91pp

Cruise From:
Was £1349pp Now: £1299pp
View cruise
REF: POR723

DEPARTS FROM UK

Cruise From:
Was £399pp Now: £387pp

Belgium And France

Southampton | Zeebrugge | Le Havre | Southampton

  • 16 Dec 2027
  • 4 Nights
  • Ventura
  • United Kingdom
  • 16 Dec 2027
  • 4 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £27pp

Cruise From:
Was £399pp Now: £387pp
View cruise
REF: PON733

DEPARTS FROM UK

Cruise From:
Was £349pp Now: £338pp

France

Southampton | Le Havre | Southampton

  • 20 Dec 2027
  • 4 Nights
  • Ventura
  • United Kingdom
  • 20 Dec 2027
  • 4 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £24pp

Cruise From:
Was £349pp Now: £338pp
View cruise
REF: PON734

DEPARTS FROM UK

Cruise From:
Was £2449pp Now: £2375pp

PRICE DROP! Christmas In Spain Madeira And Canary Islands

Southampton | La Coruña | Fuerteventura | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Funchal | Southampton

  • 21 Dec 2027
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £164pp

Cruise From:
Was £2449pp Now: £2375pp
View cruise
REF: POB733

DEPARTS FROM UK

Cruise From:
Was £1979pp Now: £1919pp

PRICE DROP! Christmas In Spain Portugal Canary Islands

Southampton | Vigo | Cádiz | Lanzarote | Santa Cruz de Tenerife | Santa Cruz de La Palma | Las Palmas de Gran Canaria | Lisbon | Southampton

  • 21 Dec 2027
  • 16 Nights
  • Arcadia
  • Mediterranean
  • 21 Dec 2027
  • 16 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £133pp

Cruise From:
Was £1979pp Now: £1919pp
View cruise
REF: POJ719

DEPARTS FROM UK

Cruise From:
Was £879pp Now: £852pp

Christmas Northern European City Escape

Southampton | Hamburg | Cherbourg | Le Havre | Southampton

  • 24 Dec 2027
  • 7 Nights
  • Ventura
  • United Kingdom
  • 24 Dec 2027
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £59pp

Cruise From:
Was £879pp Now: £852pp
View cruise
REF: V2143617122114

DEPARTS FROM UK

Cruise From:
Was £929pp Now: £899pp

New Years Eve In Hamburg

Southampton | Hamburg | Zeebrugge | Southampton

  • 29 Dec 2027
  • 5 Nights
  • Aurora
  • United Kingdom
  • 29 Dec 2027
  • 5 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Multi-Generation Cruise! From toddlers to grandparents, make more holiday memories together
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £61pp

Cruise From:
Was £929pp Now: £899pp
View cruise
REF: POR724

DEPARTS FROM UK

Cruise From:
Was £1049pp Now: £1017pp

PRICE DROP! New Year Northern Europe And Scandinavia

Southampton | Copenhagen | Oslo | Kristiansand | Southampton

  • 31 Dec 2027
  • 8 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £69pp

Cruise From:
Was £1049pp Now: £1017pp
View cruise
REF: PON736

DEPARTS FROM UK

Cruise From:
Was £8799pp Now: £8535pp

Epic South America Journey

Southampton | Las Palmas de Gran Canaria | Sao Vicente Island | Recife | Salvador de Bahia | Rio de Janeiro | Santos | Montevideo | Falkland Islands | Punta Arenas | Puerto Montt | San Antonio | Coquimbo | Arica | Callao | Fuerte Amador | Cartagena | Aruba | Curaçao | Saint George's | Bridgetown | Castries | Saint John's | Sint Maarten | Santa Cruz de Tenerife | Southampton

  • 03 Jan 2028
  • 75 Nights
  • Aurora
  • Caribbean
  • 03 Jan 2028
  • 75 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £8799pp Now: £8535pp
View cruise
REF: V218118010365

DEPARTS FROM UK

Cruise From:
Was £4299pp Now: £4170pp

Caribbean Winter Warmth

Southampton | Santa Cruz de Tenerife | Bridgetown | Martinique | Castries | Bonaire | Aruba | Saint George's | Saint Vincent | Saint John's | Saint Kitts | Sint Maarten | Tortola | Praia da Vitória | Southampton

  • 04 Jan 2028
  • 35 Nights
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £4299pp Now: £4170pp
View cruise
REF: V2157818010514
Fly Cruise From:
Was £6939pp Now: £6730pp

Southampton to Auckland

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco | Honolulu | Nawiliwili | Apia | Suva | Auckland

  • 06 Jan 2028
  • 41 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £6939pp Now: £6730pp
View cruise
REF: POJ801SOUAKL
Fly Cruise From:
Was £3879pp Now: £3762pp

Southampton to San Francisco

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco

  • 06 Jan 2028
  • 23 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £3879pp Now: £3762pp
View cruise
REF: POJ801SOUSFO

DEPARTS FROM UK

Cruise From:
Was £23839pp Now: £23123pp

Epic World Explorer

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco | Honolulu | Nawiliwili | Apia | Suva | Auckland | Tauranga | Wellington | Sydney | Airlie Beach | Cairns | Rabaul | Busan | Nagasaki | Kagoshima | Tokyo | Hong Kong | Manila | Nha Trang | Laem Chabang | Singapore | Port Klang | Colombo | Male | Mauritius | Saint-Denis de la Réunion | Durban | Gqeberha (ex Port Elizabeth) | Cape Town | Walvis Bay | Sao Vicente Island | Santa Cruz de Tenerife | Southampton

  • 06 Jan 2028
  • 124 Nights
  • Arcadia
  • Asia & Indian Ocean
  • 06 Jan 2028
  • 124 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £23839pp Now: £23123pp
View cruise
REF: V2133418010999
Fly Cruise From:
Was £8659pp Now: £8399pp

Southampton to Sydney

Southampton | Las Palmas de Gran Canaria | Bridgetown | Aruba | Manzanillo | San Diego | San Francisco | Honolulu | Nawiliwili | Apia | Suva | Auckland | Tauranga | Wellington | Sydney

  • 06 Jan 2028
  • 48 Nights
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £8659pp Now: £8399pp
View cruise
REF: POJ801SOUSYD

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Vigo | La Coruña | Southampton

  • 08 Jan 2028
  • 14 Nights
  • Ventura
  • Mediterranean
  • 08 Jan 2028
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £64pp

Cruise From:
Was £999pp Now: £969pp
View cruise
REF: V2143618010428

DEPARTS FROM UK

Cruise From:
Was £319pp Now: £309pp

Belgium and The Netherlands

Southampton | Zeebrugge | Southampton

  • 22 Jan 2028
  • 3 Nights
  • Ventura
  • United Kingdom
  • 22 Jan 2028
  • 3 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £20pp

Cruise From:
Was £319pp Now: £309pp
View cruise
REF: V214361802014

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 25 Jan 2028
  • 14 Nights
  • Ventura
  • Mediterranean
  • 25 Jan 2028
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £62pp

Cruise From:
Was £999pp Now: £969pp
View cruise
REF: V2143618020535

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

Spain Portugal And Canary Islands

Southampton | Funchal | Santa Cruz de La Palma | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Cádiz | Lisbon | Southampton

  • 08 Feb 2028
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £60pp

Cruise From:
Was £999pp Now: £969pp
View cruise
REF: V2157818011914

DEPARTS FROM UK

Cruise From:
Was £449pp Now: £435pp

Belgium and France

Southampton | Cherbourg | Le Havre | Zeebrugge | Southampton

  • 22 Feb 2028
  • 5 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £26pp

Cruise From:
Was £449pp Now: £435pp
View cruise
REF: V2157818020214

DEPARTS FROM UK

Cruise From:
Was £2099pp Now: £2036pp

Belgium and France

Southampton | Tangier | La Goulette | Valletta | Piraeus | Istanbul | Messina | Cádiz | Southampton

  • 27 Feb 2028
  • 21 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £120pp

Cruise From:
Was £2099pp Now: £2036pp
View cruise
REF: V2157818021614

DEPARTS FROM UK

Cruise From:
Was £299pp Now: £290pp

Canary Islands and Portugal

Southampton | Zeebrugge | Southampton

  • 27 Feb 2028
  • 3 Nights
  • Ventura
  • United Kingdom
  • 27 Feb 2028
  • 3 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £18pp

Cruise From:
Was £299pp Now: £290pp
View cruise
REF: V2143618032812

DEPARTS FROM UK

Cruise From:
Was £1199pp Now: £1163pp

Spain and Portugal

Southampton | Funchal | Santa Cruz de Tenerife | Las Palmas de Gran Canaria | Lanzarote | Lisbon | Vigo | La Coruña | Southampton

  • 01 Mar 2028
  • 14 Nights
  • Ventura
  • Mediterranean
  • 01 Mar 2028
  • 14 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £69pp

Cruise From:
Was £1199pp Now: £1163pp
View cruise
REF: V2143618040912

DEPARTS FROM UK

Cruise From:
Was £329pp Now: £319pp

Portugal and Canary Islands

Southampton | Zeebrugge | Southampton

  • 15 Mar 2028
  • 3 Nights
  • Ventura
  • United Kingdom
  • 15 Mar 2028
  • 3 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £19pp

Cruise From:
Was £329pp Now: £319pp
View cruise
REF: V2143618042113

DEPARTS FROM UK

Cruise From:
Was £999pp Now: £969pp

Spain, Portugal and Guernsey

Southampton | Copenhagen | Oslo | Kristiansand | Southampton

  • 18 Mar 2028
  • 7 Nights
EXTRA 10% OFF - exclusive to P&O past passengers - limited time only
Up to £400 FREE to spend on board when you book a Select Fare
Upgrade to all-inclusive classic from £49pp per day and receive Drinks, Wi-Fi and Speciality Dining
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £55pp

Cruise From:
Was £999pp Now: £969pp
View cruise
REF: V214361805047

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Why Choose P&O Cruises From The UK

Southampton is home to the most popular departure port in the UK and is another port for you to explore before or after your cruise. Cruising from Southampton allows you to avoid the fees and hassle of airports to get an early start on your cruises from the UK . P&O cruises from Southampton are perfect for many cruisers since all you have to do is drive down to the port and board your cruise. Whether you are looking for the best cruises for families or venturing out as a couple with our adult only cruises, departing aboard a P&O Cruises from Southampton makes for a more convenient and affordable holiday. Sail hassle free by opting for our all-inclusive cruises. 

P&O Cruises from Southampton destinations 

P&O Cruises from Southampton sails to many amazing destinations. You can sail closer to home on an Europe Cruise and explore popular holiday countries like Spain, France and Portugal or you can see the beauty of the Northern lights on a Norwegian Fjords cruise. If you are looking for warmer climates to escape the cold, the Caribbean is calling with our P&O cruises to the Caribbean, South American Cruises, Mediterranean Cruises, Canaries Islands Cruises and more. P&O cruises from Southampton offers World Cruises where you can explore multiple countries and learn more about the world as you traverse through the continents. Whether you are looking to sail on short break cruises or venturing out with our long duration cruises, you will find P&O cruises from Southampton that will tick all your boxes. 

Book Your P&O Cruises From Southampton

Browse through our wide range of P&O cruises from Southampton with amazing itineraries. Looking to sail a few days or 3 months in the future? Our last minute cruise deals on 2026 cruises will allow you to save more on your cruise holiday. Take advantage of our early booking discounts and save your place onboard with our low deposits when you are sailing on 2027 Cruises or 2028 Cruises. Whenever you are looking to sail, we have exclusive cruise deals on P&O cruises from Southampton.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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