Princess Cruises in the Mediterranean

Discover all Princess Cruises in the Mediterranean available at Cruise118.com below. This stunning part of the world is home to popular cruise destinations including Barcelona, Santorini, Lisbon and more. When you set sail with Princess Cruises to the Mediterranean, you can enjoy the luxuries you would expect from the Princess Cruises fleet all while soaking up the sun and diverse cultures that the Mediterranean has to offer.

Princess Cruises to the Mediterranean also include a number of cruises from Southampton offering guests a hassle-free no-fly experience directly from the UK. Cruise only holidays can be booked directly online where you can take advantage of our Cruise118.com online booking discount. Those heading further afield can speak to our cruise concierge team who will be happy to package together flights, transfers, hotel stays and more.

Showing 30 out of 435 cruises
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Fly Cruise From:
Was £1027pp Now: £991pp

7-Day Mediterranean & Adriatic

Civitavecchia | Corfu | Dubrovnik | Kotor | Naples | Civitavecchia

  • 08 Sep 2026
  • 7 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Fly Cruise From:
Was £1027pp Now: £991pp
View cruise
REF: PRINCESSN630
Cruise From:
Was £699pp Now: £674pp

7-Day Mediterranean with Greece & Italy

Athens | Santorini | Bar | Corfu | Messina | Barcelona

  • 12 Sep 2026
  • 7 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £699pp Now: £674pp
View cruise
REF: PRINCESSU636
Cruise From:
Was £1799pp Now: £1736pp

14-Day Mediterranean with Greece, France & Italy

Athens | Santorini | Bar | Corfu | Messina | Barcelona | Ibiza | Ajaccio | Marseille | Genoa | La Spezia | Civitavecchia

  • 12 Sep 2026
  • 14 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £1799pp Now: £1736pp
View cruise
REF: PRINCESSU636A

Cruise & Stay

PRICE DROP! Mediterranean, Greek Isles & Italy with Rome Stay

Holiday prices from:
£1589pp

PRICE DROP! Mediterranean, Greek Isles & Italy with Rome Stay

Civitavecchia | Naples | Dubrovnik | Split | Kotor | Corfu | Katakolon | Heraklion (Iraklion) | Mykonos | Athens

  • 13 Sep 2026
  • 12 Nights
  • Two-night 4* hotel stay in Rome
  • Seven-night full-board cruise
  • Direct return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£1589pp
View cruise
Fly Cruise From:
Was £1355pp Now: £1299pp

10-Day Mediterranean with Greek Isles & Italy

Civitavecchia | Naples | Dubrovnik | Split | Kotor | Corfu | Katakolon | Heraklion (Iraklion) | Mykonos | Athens

  • 15 Sep 2026
  • 10 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Fly Cruise From:
Was £1355pp Now: £1299pp
View cruise
REF: PRINCESSN631N
Cruise From:
Was £2280pp Now: £2199pp

21-Day The Best of the Mediterranean

Civitavecchia | Naples | Dubrovnik | Split | Kotor | Corfu | Katakolon | Heraklion (Iraklion) | Mykonos | Athens | Santorini | Kusadasi | Istanbul | Rhodes | Messina | Valletta | Civitavecchia

  • 15 Sep 2026
  • 21 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Cruise From:
Was £2280pp Now: £2199pp
View cruise
REF: PRINCESSN631B
Fly Cruise From:
Was £1494pp Now: £1441pp

7-Day Mediterranean with France & Italy

Barcelona | Ibiza | Ajaccio | Marseille | Genoa | La Spezia | Civitavecchia

  • 19 Sep 2026
  • 7 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Fly Cruise From:
Was £1494pp Now: £1441pp
View cruise
REF: PRINCESSU637
Cruise From:
Was £1499pp Now: £1446pp

14-Day Mediterranean with Greek Isles, France & Turkey

Barcelona | Ibiza | Ajaccio | Marseille | Genoa | La Spezia | Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens

  • 19 Sep 2026
  • 14 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £1499pp Now: £1446pp
View cruise
REF: PRINCESSU637A

Cruise & Stay

Cruise118.com Exclusive Savings! PRICE DROP! Mediterranean with Greek Isles & Turkey with Athens stay

Holiday prices from:
£1529pp

Cruise118.com Exclusive Savings! PRICE DROP! Mediterranean with Greek Isles & Turkey with Athens stay

Athens | Santorini | Kusadasi | Istanbul | Rhodes | Messina | Valletta | Civitavecchia

  • 23 Sep 2026
  • 13 Nights
  • Eleven-night full-board cruise
  • Two-night 4* hotel stay in Athens
  • Direct return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£1529pp
View cruise

Cruise & Stay

PRICE DROP! Mediterranean, Greek Isles & Turkey with Rome Stay

Holiday prices from:
£1519pp

PRICE DROP! Mediterranean, Greek Isles & Turkey with Rome Stay

Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens

  • 24 Sep 2026
  • 9 Nights
  • Two-night 4* hotel stay in Rome
  • Seven-night full-board cruise
  • Direct return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£1519pp
View cruise
Fly Cruise From:
Was £1426pp Now: £1376pp

11-Day Mediterranean with Greek Isles & Turkey

Athens | Santorini | Kusadasi | Istanbul | Rhodes | Messina | Valletta | Civitavecchia

  • 25 Sep 2026
  • 11 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Fly Cruise From:
Was £1426pp Now: £1376pp
View cruise
REF: PRINCESSN632N
Fly Cruise From:
Was £947pp Now: £913pp

7-Day Mediterranean with Greek Isles & Turkey

Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens

  • 26 Sep 2026
  • 7 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Fly Cruise From:
Was £947pp Now: £913pp
View cruise
REF: PRINCESSU638
Cruise From:
Was £1399pp Now: £1350pp

14-Day Mediterranean with Greek Isles, Italy & Turkey

Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens | Bar | Corfu | Messina | Naples | Barcelona

  • 26 Sep 2026
  • 14 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £1399pp Now: £1350pp
View cruise
REF: PRINCESSU638A

Cruise & Stay

PRICE DROP! Mediterranean, Greece & Italy with Athens Stay

Holiday prices from:
£1029pp

PRICE DROP! Mediterranean, Greece & Italy with Athens Stay

Athens | Bar | Corfu | Messina | Naples | Barcelona

  • 01 Oct 2026
  • 9 Nights
  • Two-night 4* hotel stay in Athens
  • Seven-night full-board cruise
  • Direct return flights with luggage allowance
  • Select private overseas transfers
Holiday prices from:
£1029pp
View cruise
Fly Cruise From:
Was £1009pp Now: £973pp

7-Day Mediterranean with Greece & Italy

Athens | Bar | Corfu | Messina | Naples | Barcelona

  • 03 Oct 2026
  • 7 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Fly Cruise From:
Was £1009pp Now: £973pp
View cruise
REF: PRINCESSU639
Cruise From:
Was £1499pp Now: £1446pp

14-Day Mediterranean with Greece, France & Italy

Athens | Bar | Corfu | Messina | Naples | Barcelona | Ibiza | Marseille | Ajaccio | Genoa | La Spezia | Civitavecchia

  • 03 Oct 2026
  • 14 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £1499pp Now: £1446pp
View cruise
REF: PRINCESSU639A

Cruise & Stay

PRICE DROP! Mediterranean & Adriatic with Rome Stay

Holiday prices from:
£1499pp

PRICE DROP! Mediterranean & Adriatic with Rome Stay

Civitavecchia | Corfu | Dubrovnik | Kotor | Naples | Civitavecchia

  • 04 Oct 2026
  • 9 Nights
  • Two-night 4* hotel stay in Rome
  • Seven-night full-board cruise
  • Direct return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£1499pp
View cruise
Cruise From:
Was £3379pp Now: £3260pp

25-Day Spain, Italy and Greece Passage

Fort Lauderdale | Kings Wharf | Ponta Delgada | Cádiz | Cartagena | Palma de Mallorca | Barcelona | Ajaccio | Portoferraio | Civitavecchia | Naples | Khania | Santorini | Mykonos | Athens

  • 06 Oct 2026
  • 25 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Cruise From:
Was £3379pp Now: £3260pp
View cruise
REF: PRINCESS2628A
Cruise From:
Was £5348pp Now: £5160pp

50-Day Grand Mediterranean Odyssey

Fort Lauderdale | Kings Wharf | Ponta Delgada | Cádiz | Cartagena | Palma de Mallorca | Barcelona | Ajaccio | Portoferraio | Civitavecchia | Naples | Khania | Santorini | Mykonos | Athens | Kusadasi | Rhodes | Corfu | Kotor | Split | Dubrovnik | Siracuse | Valletta | Gibraltar | Casablanca | Las Palmas de Gran Canaria | Fort Lauderdale

  • 06 Oct 2026
  • 50 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Cruise From:
Was £5348pp Now: £5160pp
View cruise
REF: PRINCESS2628N
Cruise From:
Was £1826pp Now: £1762pp

14-Day Mediterranean, Aegean & Adriatic

Civitavecchia | Corfu | Dubrovnik | Kotor | Naples | Civitavecchia | Salerno | Santorini | Kusadasi | Katakolon | Civitavecchia

  • 06 Oct 2026
  • 14 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Cruise From:
Was £1826pp Now: £1762pp
View cruise
REF: PRINCESSN634A
Fly Cruise From:
Was £1376pp Now: £1327pp

7-Day Mediterranean with France & Italy

Barcelona | Ibiza | Marseille | Ajaccio | Genoa | La Spezia | Civitavecchia

  • 10 Oct 2026
  • 7 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Fly Cruise From:
Was £1376pp Now: £1327pp
View cruise
REF: PRINCESSU640
Cruise From:
Was £1399pp Now: £1350pp

14-Day Mediterranean with Greek Isles, France & Turkey

Barcelona | Ibiza | Marseille | Ajaccio | Genoa | La Spezia | Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens

  • 10 Oct 2026
  • 14 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £1399pp Now: £1350pp
View cruise
REF: PRINCESSU640A
Cruise From:
Was £1999pp Now: £1929pp

21-Day The Best of the Mediterranean

Barcelona | Ibiza | Marseille | Ajaccio | Genoa | La Spezia | Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens | Bar | Corfu | Messina | Naples | Barcelona

  • 10 Oct 2026
  • 21 Nights
Last chance to book for 2026 - Limited staterooms remaining
Upgrade to Princess Plus for £55pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £1999pp Now: £1929pp
View cruise
REF: PRINCESSU640B

Cruise & Stay

PRICE DROP! Mediterranean & Aegean with Rome Stay

Holiday prices from:
£1459pp

PRICE DROP! Mediterranean & Aegean with Rome Stay

Civitavecchia | Salerno | Santorini | Kusadasi | Katakolon | Civitavecchia

  • 11 Oct 2026
  • 9 Nights
  • Two-night 4* hotel stay in Rome
  • Seven-night full-board cruise
  • Direct return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£1459pp
View cruise
Fly Cruise From:
Was £1034pp Now: £997pp

7-Day Mediterranean & Aegean

Civitavecchia | Salerno | Santorini | Kusadasi | Katakolon | Civitavecchia

  • 13 Oct 2026
  • 7 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Fly Cruise From:
Was £1034pp Now: £997pp
View cruise
REF: PRINCESSN635

Cruise & Stay

FREE Balcony Upgrade! Mediterranean, Greek Isles & Turkey with Rome Stay

Holiday prices from:
£1459pp

FREE Balcony Upgrade! Mediterranean, Greek Isles & Turkey with Rome Stay

Civitavecchia | Naples | Khania | Kusadasi | Mykonos | Athens

  • 15 Oct 2026
  • 9 Nights
  • Two-night 4* hotel stay in Rome
  • Seven-night full-board cruise
  • Direct return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£1459pp
View cruise

Cruise & Stay

PRICE DROP! Mediterranean, Greek Isles & Italy with Rome Stay

Holiday prices from:
£1499pp

PRICE DROP! Mediterranean, Greek Isles & Italy with Rome Stay

Civitavecchia | Alghero | Genoa | Livorno | Valletta | Messina | Mykonos | Rhodes | Kusadasi | Athens

  • 18 Oct 2026
  • 13 Nights
  • Two-night 4* hotel stay in Rome
  • Seven-night full-board cruise
  • Direct return flights with luggage allowance
  • Private overseas transfers
Holiday prices from:
£1499pp
View cruise
Fly Cruise From:
Was £1450pp Now: £1399pp

11-Day Mediterranean with Greek Isles & Italy

Civitavecchia | Alghero | Genoa | Livorno | Valletta | Messina | Mykonos | Rhodes | Kusadasi | Athens

  • 20 Oct 2026
  • 11 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Fly Cruise From:
Was £1450pp Now: £1399pp
View cruise
REF: PRINCESSN636N
Cruise From:
Was £2091pp Now: £2017pp

21-Day The Best of the Mediterranean

Civitavecchia | Alghero | Genoa | Livorno | Valletta | Messina | Mykonos | Rhodes | Kusadasi | Athens | Santorini | Khania | Katakolon | Corfu | Split | Dubrovnik | Kotor | Naples | Civitavecchia

  • 20 Oct 2026
  • 21 Nights
Last chance to book for 2026 - Limited staterooms remaining
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Cruise From:
Was £2091pp Now: £2017pp
View cruise
REF: PRINCESSN636B

Cruise & Stay

Half Term Mediterranean, Greece & Italy with Athens stay

Holiday prices from:
£1419pp

Half Term Mediterranean, Greece & Italy with Athens stay

Athens | Bar | Corfu | Messina | Naples | Barcelona

  • 22 Oct 2026
  • 9 Nights
  • Two-night 4* hotel stay in Athens
  • Seven-night full-board cruise
  • Direct return flights with luggage allowance
  • Select private overseas transfers
Holiday prices from:
£1419pp
View cruise

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Princess Cruises to the Mediterranean from the UK

Princess Cruises in the Mediterranean are, without a doubt, the most popular type of cruise for UK cruisers. Whether you want to sail from Southampton or enjoy a fly-cruise sailing from one of Europe's cities, we can find the perfect voyage for you.

Princess Cruises from Southampton can be booked online at Cruise118.com which is a fantastic way to take advantage of our exclusive online booking discount. Skip busy airports and delayed flights when you book Princess Cruises to the Mediterranean from the UK, simply park up at the port and board your ship.

Destinations for Princess Cruises in the Mediterranean

From exploring the Dalmatian coastline across Croatia to enjoying tapas in Spain, Princess Cruises in the Mediterranean offers something for everyone. Head to Italy and visit the Vatican Museums where you can see one of the world's greatest art collections or travel back to ancient Greece and see the Acropolis standing tall over the city of Athens, you can even explore the beautiful Greek Islands. Cruise as far as Cyprus where you'll enjoy year-round sunshine on-board Princess Cruises in the Mediterranean.

Book Princess Cruises to the Mediterranean

At Cruise118.com, we have fantastic relationships with all major cruise lines, allowing us to pass great savings onto our customers. For amazing deals on your Princess Cruises to the Mediterranean, speak to our cruising experts on 0808 239 5564 who will be more than happy to tailor your perfect holiday for you.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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