Panama Canal Cruise Deals

Choosing a Caribbean cruise with incorporates a cruise along the Panama canal can be a great idea. This magnificent feat of engineering is certainly a delight to experience, and there are also some good deals to be had, should you know where to find them.

Find Out More About Cruising The Panama Canal

Showing 30 out of 596 cruises
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Fly Cruise From:
£1799pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 06 Mar 2027
  • 7 Nights
Includes up to £865 OFF per stateroom + 3rd & 4th guest sail from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1799pp
View cruise
REF: RCIGR07D494-060327

Cruise & Stay

Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel with Santiago & Miami stays

Holiday prices from:
£4999pp

Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel with Santiago & Miami stays

San Antonio | Coquimbo | Iquique | Arica | Pisco | Callao | Fuerte Amador | Puerto Limón | San Andrés Island | Cozumel | Miami

  • 07 Mar 2027
  • 25 Nights
  • 4* hotel stays in Santiago & Miami
  • 19-night All-Inclusive cruise
  • Return flights with luggage allowance
  • Select private overseas transfers
Holiday prices from:
£4999pp
View cruise
Cruise From:
Was £1179pp Now: £1099pp

Caribbean 11 Nights From Miami, Florida

Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 07 Mar 2027
  • 11 Nights
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
Book now with a LOW £50pp deposit! - ends 31st July
Up to £90 FREE to spend on board!
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Online Exclusive! Save up to an extra £100 per cabin - limited time offer

Interest free Monthly Payments from JUST £231pp

Cruise From:
Was £1179pp Now: £1099pp
View cruise
REF: MSCPO20270307MIAMIA
Cruise From:
Was £1940pp Now: £1823pp

Caribbean 21 Nights From Miami, Florida

Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami | Willemstad | Kralendijk | Oranjestad | Cabo Rojo | Ocho Rios | Miami

  • 07 Mar 2027
  • 21 Nights
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
Book now with a LOW £50pp deposit! - ends 31st July
Up to £90 FREE to spend on board!
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £1940pp Now: £1823pp
View cruise
REF: MSCPO20270307MIAMI1
Fly Cruise From:
£1994pp

7 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Willemstad | Colón | Cartagena

  • 07 Mar 2027
  • 7 Nights
Includes up to £865 OFF per stateroom + 3rd & 4th guest sail from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1994pp
View cruise
REF: RCIGR7IP226-070327
Fly Cruise From:
Was £2535pp Now: £2433pp

11 Nt Panama Canal & Southern Caribbean

Fort Lauderdale | Cartagena | Colón | Cartagena | Oranjestad | Willemstad | Kralendijk | Fort Lauderdale

  • 08 Mar 2027
  • 11 Nights
At least 60% OFF 2nd guest PLUS up to £900 OFF per stateroom
At least 60% OFF 2nd guest PLUS up to £900 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £2535pp Now: £2433pp
View cruise
REF: CELEBAT11C025-080327
Cruise From:
Was £5539pp Now: £5317pp

31-Day Panama Canal, Inca & South America: Chilean Fjords

Buenos Aires | Montevideo | Port Stanley | Ushuaia | Port Stanley | Punta Arenas | PIO X Glacier | Puerto Montt | San Antonio | Coquimbo | General San Martin | Callao | Salaverry | Manta | Fuerte Amador | Grand Cayman | Fort Lauderdale

  • 09 Mar 2027
  • 31 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £5539pp Now: £5317pp
View cruise
REF: HALO715A
Fly Cruise From:
Was £19144pp Now: £18186pp

Journey To The Amazon

Panama City | Oranjestad | Port-of-Spain | Manaus | Boca de Valeria | Alter do Chão | Saint George's | Willemstad | Panama City

  • 09 Mar 2027
  • 22 Nights
Fly Cruise From:
Was £19144pp Now: £18186pp
View cruise
REF: REGENTGRA270309
Fly Cruise From:
Was £10439pp Now: £7899pp

Machu Picchu & Mayan Ruins

Callao | Salaverry | Guayaquil | Manta | Golfito | Panama City | Puerto Limón | Roatán Island | Harvest Caye | Costa Maya | Miami

  • 10 Mar 2027
  • 16 Nights
Fly Cruise From:
Was £10439pp Now: £7899pp
View cruise
REF: REGENTMAR270310
Cruise From:
Was £3409pp Now: £3272pp

Southern America & Panama Canal Cruise: Lima, Panama City & Cozumel

San Antonio | Coquimbo | Iquique | Arica | Pisco | Callao | Fuerte Amador | Puerto Limón | San Andrés Island | Cozumel | Miami

  • 10 Mar 2027
  • 19 Nights
Up to $1000 on board credit
Azamara Always Included: Beer, Wine & Spirits ALL day & Night | Gratuities | Variety of dining venues & 24-hour room service | Unlimited self-serve laundry | Signature AzAmazing Evenings
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £3409pp Now: £3272pp
View cruise
REF: AZJR270310-019
Cruise From:
Was £3749pp Now: £3599pp

21-Day Eastern Caribbean & Panama Canal: U.s. Virgin Islands

Fort Lauderdale | Antigua | Saint Thomas | Tortola | San Juan (Puerto Rico) | Half Moon Cay | Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Cartagena | Puerto Limón | Grand Cayman | Fort Lauderdale

  • 12 Mar 2027
  • 21 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £3749pp Now: £3599pp
View cruise
REF: HALI722A
Cruise From:
Was £911pp Now: £883pp

8-Day Caribbean & Panama

Tampa | Puerto Limón | Colón | Grand Cayman | Tampa

  • 13 Mar 2027
  • 8 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £911pp Now: £883pp
View cruise
REF: CARNIVALLE130320278
Cruise From:
Was £1330pp Now: £1299pp

11-day Cruise on Norwegian Sun

Miami | Falmouth | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 13 Mar 2027
  • 11 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Speciality Dining, Excursion Credits, and Wi-Fi
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1330pp Now: £1299pp
View cruise
REF: NCLSUN-20270313-11-MIA-MIA
Fly Cruise From:
£1917pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Willemstad | Kralendijk | Oranjestad | Colón

  • 13 Mar 2027
  • 7 Nights
Includes up to £865 OFF per stateroom + 3rd & 4th guest sail from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1917pp
View cruise
REF: RCIGR07D499-130327
Cruise From:
Was £2369pp Now: £2274pp

14-Day Panama Canal

Fort Lauderdale | Cartagena | Quepos (Puerto Quepos) | Puerto Quetzal | Huatulco (Santa María Huatulco) | Puerto Vallarta | Cabo San Lucas | San Diego

  • 14 Mar 2027
  • 14 Nights
  • Zaandam
  • Central America
  • 14 Mar 2027
  • 14 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2369pp Now: £2274pp
View cruise
REF: HALX716
Fly Cruise From:
£1991pp

7 Night Southern Caribbean Cruise

Cartagena | Willemstad | Kralendijk | Oranjestad | Colón | Cartagena

  • 14 Mar 2027
  • 7 Nights
Includes up to £865 OFF per stateroom + 3rd & 4th guest sail from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1991pp
View cruise
REF: RCIGR7IP231-140327
Fly Cruise From:
Was £3435pp Now: £3246pp

Panama & Pristine Isles

Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Falmouth | Georgetown | Miami

  • 15 Mar 2027
  • 10 Nights
Exploration Event Sale - Save up to 50%* - Book before prices increase!
Choose between a FREE house beverage package OR up to $800 shore excursion credit
Fly Cruise From:
Was £3435pp Now: £3246pp
View cruise
REF: OCEANIAMNA270315
Cruise From:
Was £6129pp Now: £5761pp

World-wide 50 Nights From Sydney, New South Wales

Sydney | Nouméa | Luganville | Pago Pago | Apia | Honolulu | Hilo | Los Angeles | Cabo San Lucas | Puntarenas | Balboa (Panama City) | La Romana | Road Town | Philipsburg | Las Palmas de Gran Canaria | Ibiza | Naples | Civitavecchia

  • 16 Mar 2027
  • 50 Nights
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
Book now with a LOW £50pp deposit! - ends 31st July
Up to £400 savings on Winter 2026/2027 Mediterranean sailings
Up to £90 FREE to spend on board!
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £6129pp Now: £5761pp
View cruise
REF: MSCMA20270316SDYCVV
Cruise From:
Was £1963pp Now: £1845pp

Caribbean 21 Nights From Miami, Florida

Miami | Willemstad | Kralendijk | Oranjestad | Cabo Rojo | Ocho Rios | Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 18 Mar 2027
  • 21 Nights
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
Book now with a LOW £50pp deposit! - ends 31st July
Up to £90 FREE to spend on board!
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Cruise From:
Was £1963pp Now: £1845pp
View cruise
REF: MSCPO20270318MIAMI1
Cruise From:
Was £1404pp Now: £1354pp

16-Day Panama Canal - Ocean to Ocean

Fort Lauderdale | Aruba | Fuerte Amador | Puntarenas | Puerto Chiapas | Huatulco (Santa María Huatulco) | Ensenada | Los Angeles

  • 18 Mar 2027
  • 16 Nights
Low deposit of £99pp Plus Up to $600 on board spend per stateroom
Online Exclusive! Save up to an extra £100 per cabin - limited time offer
Upgrade to Princess Plus for £50pp per night and receive Beverage Package, Wi-Fi, crew appreciation, plus on-board extras
Cruise From:
Was £1404pp Now: £1354pp
View cruise
REF: PRINCESS2706
Fly Cruise From:
£2979pp

Peru & Central America: Lima, Panama City & Puerto Limon

Callao | Fuerte Amador | Puerto Limón | San Andrés Island | Cozumel | Miami

  • 18 Mar 2027
  • 11 Nights
Up to $1000 on board credit
Azamara Always Included: Beer, Wine & Spirits ALL day & Night | Gratuities | Variety of dining venues & 24-hour room service | Unlimited self-serve laundry | Signature AzAmazing Evenings
Fly Cruise From:
£2979pp
View cruise
REF: AZJR270318-011
Fly Cruise From:
£1799pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 20 Mar 2027
  • 7 Nights
Includes up to £865 OFF per stateroom + 3rd & 4th guest sail from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1799pp
View cruise
REF: RCIGR07D494-200327
Fly Cruise From:
£16611pp

Ultimate South America to the Caribbean through the Panama Canal

Valparaiso | Pingüino de Humboldt National Reserve | Paracas | Salaverry | Manta | Utría National Park | Ensenada de Utria | Darién National Park | Playa del Muerto | Panama City | San Blas Islands | Cartagena | Cabo de la Vela | Willemstad | Tobago Cays | Mayreau Island | Soufrière | Bridgetown

  • 21 Mar 2027
  • 24 Nights
Fly Cruise From:
£16611pp
View cruise
REF: SCENIC132C210327-2
Fly Cruise From:
£8986pp

Ancient Kingdoms and Natural Treasures: Chile to Panama

Valparaiso | Pingüino de Humboldt National Reserve | Paracas | Salaverry | Manta | Utría National Park | Ensenada de Utria | Darién National Park | Playa del Muerto | Panama City

  • 21 Mar 2027
  • 13 Nights
Fly Cruise From:
£8986pp
View cruise
REF: SCENIC801L210327-2
Cruise From:
Was £2409pp Now: £2312pp

12-Day Panama Canal Discovery: Costa Rica & Greater Antilles

Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Puerto Limón | Grand Cayman | Fort Lauderdale

  • 21 Mar 2027
  • 12 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2409pp Now: £2312pp
View cruise
REF: HALI723
Cruise From:
Was £3759pp Now: £3599pp

21-Day Panama Canal & Southern Caribbean: Abc Islands

Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Puerto Limón | Grand Cayman | Fort Lauderdale | Bonaire | Curaçao | Cabo Rojo | Half Moon Cay | Fort Lauderdale

  • 21 Mar 2027
  • 21 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £3759pp Now: £3599pp
View cruise
REF: HALI723A
Fly Cruise From:
£1934pp

7 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Willemstad | Colón | Cartagena

  • 21 Mar 2027
  • 7 Nights
Includes up to £865 OFF per stateroom + 3rd & 4th guest sail from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1934pp
View cruise
REF: RCIGR7IP226-210327
Cruise From:
Was £1355pp Now: £1327pp

Panama Canal: Mexico, Jamaica & Costa Rica

Miami | Ocho Rios | Georgetown | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 24 Mar 2027
  • 12 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Speciality Dining, Excursion Credits, and Wi-Fi
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1355pp Now: £1327pp
View cruise
REF: NCLSUN-20270324-12-MIA-MIA
Cruise From:
Was £2839pp Now: £2725pp

16-Day Inca & Panama Canal Discovery: Lima Overnight

San Antonio | Coquimbo | General San Martin | Callao | Salaverry | Manta | Fuerte Amador | Grand Cayman | Fort Lauderdale

  • 24 Mar 2027
  • 16 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2839pp Now: £2725pp
View cruise
REF: HALO718

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

Here at Cruise118, our relationships with the cruise lines means that we have exclusive access to some unbelievable cruise deals and discounts. We can plan every aspect of your Panama Canal cruise holiday, ensuring that you get the best deal for you at the very best price. So please, don't hesitate to give us a call.

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