South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2493 cruises
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Was £6174pp Now: £5988pp

In Darwin’s Footsteps (Eastern Route)

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 16 Dec 2026
  • 13 Nights
Cruise From:
Was £6174pp Now: £5988pp
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REF: HX978777978798-2
Cruise From:
Was £994pp Now: £934pp

South America 7 Nights From Maceió

Maceió | Santos | Buzios | Salvador de Bahia | Maceió

  • 16 Dec 2026
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £994pp Now: £934pp
View cruise
REF: MSCVI20261216MCZMCZ
Fly Cruise From:
Was £10990pp Now: £10550pp

Antarctic Explorer

Ushuaia | Antarctic Experience | Antarctica | Antarctic Experience | Antarctica | Ushuaia

  • 16 Dec 2026
  • 11 Nights
Fly Cruise From:
Was £10990pp Now: £10550pp
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REF: VIKINGXOC261216T
Cruise From:
Was £1064pp Now: £999pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Punta del Este | Buenos Aires

  • 17 Dec 2026
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1064pp Now: £999pp
View cruise
REF: MSCSV20261217BUEBUE
Cruise From:
Was £414pp Now: £393pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 17 Dec 2026
  • 3 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £97pp

Cruise From:
Was £414pp Now: £393pp
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REF: MSCMU20261217SSZSSZ
Cruise From:
Was £839pp Now: £799pp

12-Day Panama Canal with Costa Rica & Caribbean Holiday

Fort Lauderdale | Aruba | Cartagena | Colón | Cartagena | Puerto Limón | Grand Cayman | Fort Lauderdale

  • 17 Dec 2026
  • 12 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £839pp Now: £799pp
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REF: PRINCESSB641
Cruise From:
Was £161pp Now: £156pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 17 Dec 2026
  • 3 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £161pp Now: £156pp
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REF: CARNIVALRD171220263
Cruise From:
Was £13797pp Now: £12279pp

10-Day The Great White Continent

Buenos Aires | Ushuaia | Antarctic Experience | Buenos Aires | Ushuaia

  • 18 Dec 2026
  • 11 Nights
Receive up to $1,000 onboard spend per couple
Cruise From:
Was £13797pp Now: £12279pp
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REF: SBNV664
Cruise From:
Was £167pp Now: £161pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 18 Dec 2026
  • 3 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £167pp Now: £161pp
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REF: CARNIVALFN181220263
Cruise From:
£341pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 18 Dec 2026
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £67pp

Cruise From:
£341pp
View cruise
REF: RCIOV03X041-181226
Cruise From:
£268pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 18 Dec 2026
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £42pp

Cruise From:
£268pp
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REF: RCIVY03X046-181226
Fly Cruise From:
Was £4273pp Now: £4069pp

Panama Canal Holiday Cruise: Miami, Cabo Rojo & San Diego

Miami | Cabo Rojo | Cartagena | Puntarenas | Puerto Quetzal | Puerto Vallarta | San Diego | San Francisco

  • 18 Dec 2026
  • 18 Nights
Azamara Always Included: Beer, Wine & Spirits ALL day & Night | Gratuities | Variety of dining venues & 24-hour room service | Unlimited self-serve laundry | Signature AzAmazing Evenings
Fly Cruise From:
Was £4273pp Now: £4069pp
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REF: AZQS261218-018
Cruise From:
Was £5179pp Now: £4971pp

22-Day South America & Antarctica Holiday

Buenos Aires | Montevideo | Punta del Este | Puerto Madryn | Port Stanley | Antarctic Experience | Ushuaia | Punta Arenas | Puerto Chacabuco | Puerto Montt | San Antonio

  • 19 Dec 2026
  • 22 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £5179pp Now: £4971pp
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REF: HALO674
Fly Cruise From:
Was £6795pp Now: £6523pp

South America & the Chilean Fjords

Valparaiso | Puerto Montt | Ushuaia | Port Stanley | Puerto Madryn | Montevideo | Buenos Aires

  • 19 Dec 2026
  • 17 Nights
Fly Cruise From:
Was £6795pp Now: £6523pp
View cruise
REF: VIKINGOJU261219
Cruise From:
Was £874pp Now: £821pp

South America 7 Nights From Santos

Santos | Buzios | Salvador de Bahia | Maceió | Santos

  • 19 Dec 2026
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £232pp

Cruise From:
Was £874pp Now: £821pp
View cruise
REF: MSCVI20261219SSZSSZ
Cruise From:
Was £1355pp Now: £1273pp

South America 8 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires

  • 19 Dec 2026
  • 8 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1355pp Now: £1273pp
View cruise
REF: MSCSP20261219BUEBUE
Cruise From:
Was £595pp Now: £577pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 19 Dec 2026
  • 8 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £595pp Now: £577pp
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REF: CARNIVALPO191220268
Cruise From:
Was £629pp Now: £606pp

7-Day Mexican Riviera Holiday

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 19 Dec 2026
  • 7 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £233pp

Cruise From:
Was £629pp Now: £606pp
View cruise
REF: PRINCESSX645
Fly Cruise From:
£1933pp

7 Nt Southern Caribbean Holiday Cruise

Colón | Cartagena | Oranjestad | Kralendijk | Colón

  • 19 Dec 2026
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1933pp
View cruise
REF: RCIGR07D491-191226
Cruise From:
Was £10350pp Now: £9832pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 19 Dec 2026
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10350pp Now: £9832pp
View cruise
REF: SILVEROR261219007
Fly Cruise From:
Was £5809pp Now: £5576pp

14 Night Patagonia & Argentina Holiday - Christmas at Sea

Buenos Aires | Montevideo | Port Stanley | Ushuaia | Punta Arenas | Puerto Madryn | Punta del Este | Buenos Aires

  • 19 Dec 2026
  • 14 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £5809pp Now: £5576pp
View cruise
REF: CELEBEQ14F119-191226
Cruise From:
Was £1289pp Now: £1237pp

7-Day Baja Peninsula Holiday

San Diego | Cabo San Lucas | La Paz | Loreto | San Diego

  • 19 Dec 2026
  • 7 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1289pp Now: £1237pp
View cruise
REF: HALK686
Cruise From:
Was £2589pp Now: £2485pp

14-Day Mexican Riviera & Baja Peninsula Holiday

San Diego | Cabo San Lucas | La Paz | Loreto | San Diego | Puerto Vallarta | Mazatlán | Cabo San Lucas | San Diego

  • 19 Dec 2026
  • 14 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2589pp Now: £2485pp
View cruise
REF: HALK686A
Fly Cruise From:
Was £5469pp Now: £5168pp

Antilles To Andes

Miami | Key West | Willemstad | Oranjestad | Santa Marta | Cartagena | Manta | Guayaquil | Callao

  • 19 Dec 2026
  • 15 Nights
ENDS 30th June - Save up to 50%* - book before prices increase!
Choose between a FREE house beverage package OR up to $800 shore excursion credit
Fly Cruise From:
Was £5469pp Now: £5168pp
View cruise
REF: OCEANIAINS261219
Fly Cruise From:
Was £10289pp Now: £9723pp

Caribbean To Cape Horn

Miami | Key West | Willemstad | Oranjestad | Santa Marta | Cartagena | Manta | Guayaquil | Callao | Pisco | Coquimbo | San Antonio | Puerto Montt | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Port Stanley | Puerto Madryn | Punta del Este | Buenos Aires

  • 19 Dec 2026
  • 36 Nights
Choose between a FREE house beverage package OR up to $800 shore excursion credit
Fly Cruise From:
Was £10289pp Now: £9723pp
View cruise
REF: OCEANIAINS261219A
Cruise From:
Was £2589pp Now: £2485pp

15-Day Panama Canal Holiday

San Diego | Cabo San Lucas | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Quetzal | Puntarenas | Cartagena | Fort Lauderdale

  • 19 Dec 2026
  • 15 Nights
  • Zaandam
  • Central America
  • 19 Dec 2026
  • 15 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2589pp Now: £2485pp
View cruise
REF: HALX682
Cruise From:
Was £804pp Now: £755pp

South America 7 Nights From Santos

Santos | Camboriú | Punta del Este | Buenos Aires | Santos

  • 20 Dec 2026
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £209pp

Cruise From:
Was £804pp Now: £755pp
View cruise
REF: MSCSV20261220SSZSSZ
Cruise From:
Was £634pp Now: £595pp

South America 7 Nights From Santos

Santos | Ilhabela | Rio de Janeiro | Ilha Grande | Buzios | Paranaguá | Itajai

  • 20 Dec 2026
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £158pp

Cruise From:
Was £634pp Now: £595pp
View cruise
REF: MSCMU20261220SSZITJ
Cruise From:
Was £669pp Now: £635pp

South America 6 Nights From Santos

Santos | Ilhabela | Rio de Janeiro | Ilha Grande | Buzios | Paranaguá

  • 20 Dec 2026
  • 6 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £171pp

Cruise From:
Was £669pp Now: £635pp
View cruise
REF: MSCMU20261220SSZPNG
Cruise From:
Was £7004pp Now: £6723pp

7 Night Galapagos Inner Loop Cruise - Christmas at Sea

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 20 Dec 2026
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £7004pp Now: £6723pp
View cruise
REF: CELEBFL07G057-201226

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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