South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2493 cruises
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Fly Cruise From:
Was £7929pp Now: £7691pp

Hamburg To Sydney

Hamburg | Southampton | Ponta Delgada | Port Canaveral | Miami | Cartagena | Puerto Quetzal | Manzanillo | Los Angeles | Kailua-Kona | Honolulu | Lautoka | Sydney

  • 09 Jan 2028
  • 47 Nights
Receive up to $250 FREE to spend on board
Cunard Signature Packages Beverage Package | Wi-Fi Plan | Speciality Dining Credit from just £60pp per day
Summer 2028 Collection now on sale - early bookings savings of 10% - limited time offer
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £7929pp Now: £7691pp
View cruise
REF: CUNARDH802E
Fly Cruise From:
Was £14409pp Now: £13976pp

Full World Voyage

Hamburg | Southampton | Ponta Delgada | Port Canaveral | Miami | Cartagena | Puerto Quetzal | Manzanillo | Los Angeles | Kailua-Kona | Honolulu | Lautoka | Sydney | Brisbane | Airlie Beach | Yorkeys Knob | Bitung | Manila | Hong Kong | Laem Chabang | Ko Samui | Singapore | Port Klang | Georgetown | Mauritius | Pointe des Galets | Durban | Gqeberha (ex Port Elizabeth) | Cape Town | Sao Vicente Island | Las Palmas de Gran Canaria | Funchal | Southampton | Hamburg

  • 09 Jan 2028
  • 114 Nights
Cunard Signature Packages Beverage Package | Wi-Fi Plan | Speciality Dining Credit from just £60pp per day
Summer 2028 Collection now on sale - early bookings savings of 10% - limited time offer
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £14409pp Now: £13976pp
View cruise
REF: CUNARDH802F
Fly Cruise From:
£24889pp

Vibrant Wonders of Peru & Antarctica - Cruise & Land Lourney

Lima | Machu Picchu | Cuzco | Machu Picchu | Cuzco | Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 09 Jan 2028
  • 21 Nights
Fly Cruise From:
£24889pp
View cruise
REF: SCENICOSL1090128-1
Cruise From:
Was £7175pp Now: £6888pp

7 Night Galapagos Outer Loop Itinerary

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 09 Jan 2028
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £7175pp Now: £6888pp
View cruise
REF: CELEBFL07G062-090128
Cruise From:
Was £380pp Now: £368pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 09 Jan 2028
  • 6 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £380pp Now: £368pp
View cruise
REF: CARNIVALPO090120286
Cruise From:
£1669pp

Panama Canal: Mexico & Costa Rica

Los Angeles | Cabo San Lucas | Acapulco | Puerto Quetzal | Puerto Caldera | Panama City | Cartagena | Miami

  • 09 Jan 2028
  • 15 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £101pp

Cruise From:
£1669pp
View cruise
REF: NCLENC-20280109-15-LAX-MIA
Fly Cruise From:
Was £12990pp Now: £12470pp

Antarctic Explorer

Ushuaia | Antarctic Experience | Antarctica | Antarctic Experience | Antarctica | Ushuaia

  • 09 Jan 2028
  • 11 Nights
Fly Cruise From:
Was £12990pp Now: £12470pp
View cruise
REF: VIKINGXPO280109T
Cruise From:
£709pp

7 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Willemstad | Colón | Cartagena

  • 09 Jan 2028
  • 7 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £36pp

Cruise From:
£709pp
View cruise
REF: RCIGR07I198-090128
Cruise From:
Was £267pp Now: £258pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 10 Jan 2028
  • 4 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £267pp Now: £258pp
View cruise
REF: CARNIVALRD100120284
Cruise From:
£262pp

4 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 10 Jan 2028
  • 4 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £8pp

Cruise From:
£262pp
View cruise
REF: RCIOV04X068-100128
Fly Cruise From:
Was £3529pp Now: £3423pp

Southampton To Los Angeles

Southampton | Ponta Delgada | Port Canaveral | Miami | Cartagena | Puerto Quetzal | Manzanillo | Los Angeles

  • 11 Jan 2028
  • 27 Nights
Receive up to $250 FREE to spend on board
Cunard Signature Packages Beverage Package | Wi-Fi Plan | Speciality Dining Credit from just £60pp per day
Summer 2028 Collection now on sale - early bookings savings of 10% - limited time offer
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £196pp

Fly Cruise From:
Was £3529pp Now: £3423pp
View cruise
REF: CUNARDH803A
Fly Cruise From:
Was £8499pp Now: £8244pp

Southampton To Sydney

Southampton | Ponta Delgada | Port Canaveral | Miami | Cartagena | Puerto Quetzal | Manzanillo | Los Angeles | Kailua-Kona | Honolulu | Lautoka | Sydney

  • 11 Jan 2028
  • 45 Nights
Receive up to $250 FREE to spend on board
Cunard Signature Packages Beverage Package | Wi-Fi Plan | Speciality Dining Credit from just £60pp per day
Summer 2028 Collection now on sale - early bookings savings of 10% - limited time offer
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £8499pp Now: £8244pp
View cruise
REF: CUNARDH803B
Fly Cruise From:
Was £7669pp Now: £7438pp

Southampton To Hong Kong

Southampton | Ponta Delgada | Port Canaveral | Miami | Cartagena | Puerto Quetzal | Manzanillo | Los Angeles | Kailua-Kona | Honolulu | Lautoka | Sydney | Brisbane | Airlie Beach | Yorkeys Knob | Bitung | Manila | Hong Kong

  • 11 Jan 2028
  • 62 Nights
Receive up to $250 FREE to spend on board
Cunard Signature Packages Beverage Package | Wi-Fi Plan | Speciality Dining Credit from just £60pp per day
Summer 2028 Collection now on sale - early bookings savings of 10% - limited time offer
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £7669pp Now: £7438pp
View cruise
REF: CUNARDH803C

DEPARTS FROM UK

Cruise From:
Was £10599pp Now: £10281pp

Full World Voyage

Southampton | Ponta Delgada | Port Canaveral | Miami | Cartagena | Puerto Quetzal | Manzanillo | Los Angeles | Kailua-Kona | Honolulu | Lautoka | Sydney | Brisbane | Airlie Beach | Yorkeys Knob | Bitung | Manila | Hong Kong | Laem Chabang | Ko Samui | Singapore | Port Klang | Georgetown | Mauritius | Pointe des Galets | Durban | Gqeberha (ex Port Elizabeth) | Cape Town | Sao Vicente Island | Las Palmas de Gran Canaria | Funchal | Southampton

  • 11 Jan 2028
  • 110 Nights
Cunard Signature Packages Beverage Package | Wi-Fi Plan | Speciality Dining Credit from just £60pp per day
Summer 2028 Collection now on sale - early bookings savings of 10% - limited time offer
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £10599pp Now: £10281pp
View cruise
REF: CUNARDH803D
Cruise From:
£55000pp

Roundtrip Fort Lauderdale

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete | Moorea | Raiatea | Bora-Bora | Pago Pago | Suva | Lautoka | Port Vila | Lifou Island | Nouméa | Pine Island | Bay of Islands | Auckland | Napier | Wellington | Melbourne | Portland | Adelaide | Kangaroo Island | Albany | Fremantle | Geraldton | Bali | Celukan Bawang | Puerto Princesa | Boracay Island | Manila | Nha Trang | Ho Chi Minh City | Singapore | Port Klang | Georgetown | Phuket | Port Blair | Hambantota | Colombo | Cochin | New Mangalore | Goa | Mumbai (ex Bombay) | Khasab | Abu Dhabi | Dubai | Fujairah | Muscat | Salalah | Jeddah | 'Aqaba | Luxor | Alexandria | Soúda | Katakolon | Siracuse | Valletta | Tunis | Trapani | Lipari | Sorrento | Civitavecchia | Barcelona | Alicante | Motril | Ponta Delgada | Horta | Kings Wharf | Fort Lauderdale

  • 11 Jan 2028
  • 150 Nights
Cruise From:
£55000pp
View cruise
REF: CRYSTALCSY-W150-280111
Cruise From:
£53000pp

Fort Lauderdale to Barcelona

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete | Moorea | Raiatea | Bora-Bora | Pago Pago | Suva | Lautoka | Port Vila | Lifou Island | Nouméa | Pine Island | Bay of Islands | Auckland | Napier | Wellington | Melbourne | Portland | Adelaide | Kangaroo Island | Albany | Fremantle | Geraldton | Bali | Celukan Bawang | Puerto Princesa | Boracay Island | Manila | Nha Trang | Ho Chi Minh City | Singapore | Port Klang | Georgetown | Phuket | Port Blair | Hambantota | Colombo | Cochin | New Mangalore | Goa | Mumbai (ex Bombay) | Khasab | Abu Dhabi | Dubai | Fujairah | Muscat | Salalah | Jeddah | 'Aqaba | Luxor | Alexandria | Soúda | Katakolon | Siracuse | Valletta | Tunis | Trapani | Lipari | Sorrento | Civitavecchia | Barcelona

  • 11 Jan 2028
  • 136 Nights
Cruise From:
£53000pp
View cruise
REF: CRYSTALCSY-W136-280111
Cruise From:
£34900pp

Fort Lauderdale to Singapore

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete | Moorea | Raiatea | Bora-Bora | Pago Pago | Suva | Lautoka | Port Vila | Lifou Island | Nouméa | Pine Island | Bay of Islands | Auckland | Napier | Wellington | Melbourne | Portland | Adelaide | Kangaroo Island | Albany | Fremantle | Geraldton | Bali | Celukan Bawang | Puerto Princesa | Boracay Island | Manila | Nha Trang | Ho Chi Minh City | Singapore

  • 11 Jan 2028
  • 85 Nights
Cruise From:
£34900pp
View cruise
REF: CRYSTALCSY-G85-280111
Cruise From:
£9519pp

Fort Lauderdale to Papeete, Tahiti

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao | Hangaroa | Adamstown | Fakarava | Rangiroa | Huahine | Papeete

  • 11 Jan 2028
  • 33 Nights
Cruise From:
£9519pp
View cruise
REF: CRYSTALCSY-C33-280111
Cruise From:
Was £15360pp Now: £14592pp

Puerto Williams to Puerto Williams

Puerto Williams | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 11 Jan 2028
  • 10 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £15360pp Now: £14592pp
View cruise
REF: SILVERE4280111010
Cruise From:
£6184pp

Fort Lauderdale to Callao (Lima)

Fort Lauderdale | Cozumel | Belize City | Santo Tomás de Castilla | Roatán Island | Puerto Limón | Cartagena | Fuerte Amador | Cartagena | Fuerte Amador | Manta | Guayaquil | Salaverry | Callao

  • 11 Jan 2028
  • 18 Nights
Cruise From:
£6184pp
View cruise
REF: CRYSTALCSY-018-280111
Fly Cruise From:
£24772pp

Grenadines, Colombia & Panama Canal transit

Bridgetown | Port Elizabeth | Mayreau Island | Kralendijk | Willemstad | Oranjestad | Santa Marta | Cartagena | San Blas Islands | Panama City

  • 13 Jan 2028
  • 11 Nights
Fly Cruise From:
£24772pp
View cruise
REF: EMERALDE02C130128-2
Fly Cruise From:
£39960pp

Discover the Secrets of Panama and Costa Rica

Bridgetown | Port Elizabeth | Mayreau Island | Kralendijk | Willemstad | Oranjestad | Santa Marta | Cartagena | San Blas Islands | Panama City | Pearl Islands | Darién National Park | Playa del Muerto | Cébaco Island | Golfito | Quepos (Puerto Quepos) | Tortuga Island | Puerto Caldera

  • 13 Jan 2028
  • 18 Nights
Fly Cruise From:
£39960pp
View cruise
REF: EMERALD2C02130128-2
Cruise From:
Was £899pp Now: £867pp

12-Day Southern Caribbean with Panama

Fort Lauderdale | Aruba | Cartagena | Colón | Puerto Limón | Grand Cayman | Cozumel | Fort Lauderdale

  • 13 Jan 2028
  • 12 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £50pp

Cruise From:
Was £899pp Now: £867pp
View cruise
REF: V2331618011314
Cruise From:
Was £238pp Now: £230pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 14 Jan 2028
  • 3 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £238pp Now: £230pp
View cruise
REF: CARNIVALRD140120283
Cruise From:
£469pp

7 Night Mexican Riviera Cruise

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 14 Jan 2028
  • 7 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £21pp

Cruise From:
£469pp
View cruise
REF: RCINV07X090-140128
Cruise From:
£322pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 14 Jan 2028
  • 3 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £11pp

Cruise From:
£322pp
View cruise
REF: RCIOV03X054-140128
Cruise From:
Was £4099pp Now: £3935pp

21-Day Southern Caribbean & Panama Canal: Abc Islands

Fort Lauderdale | Bonaire | Curaçao | Aruba | Half Moon Cay | Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Cartagena | Puerto Limón | Grand Cayman | Fort Lauderdale

  • 14 Jan 2028
  • 21 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £241pp

Cruise From:
Was £4099pp Now: £3935pp
View cruise
REF: HALO816A
Cruise From:
Was £2549pp Now: £2447pp

Panama, Ecuadaor & Peru Cruise: Panama City, Manta & Lima (Callao)

Fuerte Amador | Manta | Callao | Pisco | Coquimbo | Valparaiso

  • 14 Jan 2028
  • 10 Nights
Azamara Always Included: Beer, Wine & Spirits ALL day & Night | Gratuities | Variety of dining venues & 24-hour room service | Unlimited self-serve laundry | Signature AzAmazing Evenings
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2549pp Now: £2447pp
View cruise
REF: AZQS280114-010
Cruise From:
Was £24297pp Now: £21624pp

20-Day Ultimate Antarctica, Falklands & South Georgia

Buenos Aires | Ushuaia | Antarctic Experience | South Georgia Experience | Port Stanley | Falkland Islands | Buenos Aires | Ushuaia

  • 15 Jan 2028
  • 21 Nights
Receive up to $1,000 onboard spend per couple
Cruise From:
Was £24297pp Now: £21624pp
View cruise
REF: SBNP812
Cruise From:
Was £749pp Now: £722pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 15 Jan 2028
  • 7 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £41pp

Cruise From:
Was £749pp Now: £722pp
View cruise
REF: PRINCESSX803

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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