South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2496 cruises
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Cruise From:
Was £4139pp Now: £3973pp

22-Day Panama Canal

Fort Lauderdale | Cartagena | Puntarenas | Acajutla | Puerto Quetzal | Acapulco | Puerto Vallarta | Cabo San Lucas | San Diego | Santa Barbara | Astoria | Victoria | Vancouver

  • 01 Apr 2028
  • 22 Nights
  • Eurodam
  • Central America
  • 01 Apr 2028
  • 22 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £208pp

Cruise From:
Was £4139pp Now: £3973pp
View cruise
REF: HALD832
Cruise From:
Was £3319pp Now: £3186pp

16-Day Panama Canal

Fort Lauderdale | Cartagena | Puntarenas | Acajutla | Puerto Quetzal | Acapulco | Puerto Vallarta | Cabo San Lucas | San Diego

  • 01 Apr 2028
  • 16 Nights
  • Eurodam
  • Central America
  • 01 Apr 2028
  • 16 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £167pp

Cruise From:
Was £3319pp Now: £3186pp
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REF: HALD832A
Cruise From:
Was £1399pp Now: £1343pp

7-Day Mexican Riviera

San Diego | Cabo San Lucas | Mazatlán | Puerto Vallarta | San Diego

  • 01 Apr 2028
  • 7 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £71pp

Cruise From:
Was £1399pp Now: £1343pp
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REF: HALK820B
Cruise From:
Was £490pp Now: £475pp

Mexico & Bimini Beach Club

Miami | Cozumel | Bimini Island | Miami

  • 01 Apr 2028
  • 5 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £24pp

Cruise From:
Was £490pp Now: £475pp
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REF: VIRGINVL280401
Cruise From:
Was £8983pp Now: £8623pp

7 Night Galapagos Outer Loop Itinerary

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 02 Apr 2028
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £8983pp Now: £8623pp
View cruise
REF: CELEBFL07G062-020428
Cruise From:
Was £455pp Now: £441pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 02 Apr 2028
  • 6 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £455pp Now: £441pp
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REF: CARNIVALPO020420286
Cruise From:
£645pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 02 Apr 2028
  • 7 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £30pp

Cruise From:
£645pp
View cruise
REF: NCLENC-20280402-07-LAX-LAX
Cruise From:
£782pp

7 Night Southern Caribbean Cruise

Cartagena | Kralendijk | Oranjestad | Willemstad | Colón | Cartagena

  • 02 Apr 2028
  • 7 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £35pp

Cruise From:
£782pp
View cruise
REF: RCIGR07I201-020428
Cruise From:
Was £357pp Now: £346pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 03 Apr 2028
  • 4 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £357pp Now: £346pp
View cruise
REF: CARNIVALRD030420284
Cruise From:
£306pp

4 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 03 Apr 2028
  • 4 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £9pp

Cruise From:
£306pp
View cruise
REF: RCIOV04X067-030428
Fly Cruise From:
£6887pp

Wellness Retreat: Rio to Santa Cruz de Tenerife

Rio de Janeiro | Santa Cruz de Tenerife

  • 06 Apr 2028
  • 12 Nights
Fly Cruise From:
£6887pp
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REF: SCENIC111R060428-1
Cruise From:
Was £1499pp Now: £1399pp

World-wide 18 Nights From Miami, Florida

Miami | Cartagena | Colón | Puntarenas | Cabo San Lucas | San Diego | San Francisco | Seattle

  • 06 Apr 2028
  • 18 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £70pp

Cruise From:
Was £1499pp Now: £1399pp
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REF: MSCPO20280406MIASEA
Cruise From:
Was £298pp Now: £289pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 07 Apr 2028
  • 3 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £298pp Now: £289pp
View cruise
REF: CARNIVALRD070420283
Fly Cruise From:
£1646pp

7 Night Mexican Riviera Cruise

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 07 Apr 2028
  • 7 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £81pp

Fly Cruise From:
£1646pp
View cruise
REF: RCINV07X090-070428
Cruise From:
£408pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 07 Apr 2028
  • 3 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £14pp

Cruise From:
£408pp
View cruise
REF: RCIOV03X054-070428
Fly Cruise From:
Was £9990pp Now: £9590pp

Panama Canal & the Americas

Valparaiso | Iquique | Callao | Fuerte Amador | Port Antonio | Inagua | San Salvador Island | New York

  • 07 Apr 2028
  • 19 Nights
Fly Cruise From:
Was £9990pp Now: £9590pp
View cruise
REF: VIKINGXPO280407
Cruise From:
Was £749pp Now: £722pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 08 Apr 2028
  • 7 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £35pp

Cruise From:
Was £749pp Now: £722pp
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REF: PRINCESSX815
Cruise From:
Was £679pp Now: £658pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 08 Apr 2028
  • 8 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £679pp Now: £658pp
View cruise
REF: CARNIVALPO080420288
Cruise From:
£768pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Willemstad | Oranjestad | Colón

  • 08 Apr 2028
  • 7 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £34pp

Cruise From:
£768pp
View cruise
REF: RCIGR07D549-080428
Fly Cruise From:
Was £9990pp Now: £9590pp

Panama Canal & the Americas

Valparaiso | Iquique | Callao | Fuerte Amador | Port Antonio | Inagua | San Salvador Island | New York

  • 08 Apr 2028
  • 19 Nights
Fly Cruise From:
Was £9990pp Now: £9590pp
View cruise
REF: VIKINGXOC280408
Cruise From:
Was £8932pp Now: £8574pp

7 Night Galapagos Inner Loop Itinerary

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 09 Apr 2028
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £8932pp Now: £8574pp
View cruise
REF: CELEBFL07G061-090428
Cruise From:
£660pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Puerto Vallarta | Mazatlán | Cabo San Lucas | Los Angeles

  • 09 Apr 2028
  • 7 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £31pp

Cruise From:
£660pp
View cruise
REF: NCLENC-20280409-07-LAX-LAX
Cruise From:
Was £518pp Now: £502pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 09 Apr 2028
  • 6 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £518pp Now: £502pp
View cruise
REF: CARNIVALLE090420286
Cruise From:
£799pp

7 Night Southern Caribbean Cruise

Cartagena | Willemstad | Oranjestad | Colón | Cartagena

  • 09 Apr 2028
  • 7 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £35pp

Cruise From:
£799pp
View cruise
REF: RCIGR07I197-090428
Cruise From:
Was £357pp Now: £346pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 10 Apr 2028
  • 4 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £357pp Now: £346pp
View cruise
REF: CARNIVALRD100420284
Cruise From:
£296pp

4 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 10 Apr 2028
  • 4 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £8pp

Cruise From:
£296pp
View cruise
REF: RCIOV04X067-100428
Cruise From:
Was £298pp Now: £289pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 14 Apr 2028
  • 3 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £298pp Now: £289pp
View cruise
REF: CARNIVALRD140420283
Fly Cruise From:
£1646pp

7 Night Mexican Riviera Cruise

Los Angeles | Cabo San Lucas | Mazatlán | Ensenada | Los Angeles

  • 14 Apr 2028
  • 7 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £80pp

Fly Cruise From:
£1646pp
View cruise
REF: RCINV07X091-140428
Cruise From:
£392pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 14 Apr 2028
  • 3 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £13pp

Cruise From:
£392pp
View cruise
REF: RCIOV03X054-140428
Cruise From:
£1815pp

Panama Canal: Mexico & Costa Rica

New York | Puerto Plata | Cartagena | Colón | Puerto Caldera | Puerto Quetzal | Acapulco | Cabo San Lucas | San Francisco

  • 14 Apr 2028
  • 19 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £92pp

Cruise From:
£1815pp
View cruise
REF: NCLBLS-20280414-19-NYC-SFO

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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