South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2496 cruises
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Cruise From:
Was £297pp Now: £288pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 22 Nov 2026
  • 6 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £297pp Now: £288pp
View cruise
REF: CARNIVALRD221120266
Cruise From:
£615pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 22 Nov 2026
  • 7 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
£615pp
View cruise
REF: NCLENC-20261122-07-LAX-LAX
Cruise From:
£628pp

7 Night Cabo, Mazatlan & La Paz Cruise

San Diego | Cabo San Lucas | La Paz | Mazatlán | San Diego

  • 22 Nov 2026
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £237pp

Cruise From:
£628pp
View cruise
REF: RCISR07X072-221126
Cruise From:
Was £5609pp Now: £5384pp

30-Day Legendary Amazon Explorer

New York | Fort Lauderdale | Sint Maarten | Fort-de-France | Bridgetown | Macapa | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Icoaraci | Devil's Island | Curaçao | Fort Lauderdale

  • 22 Nov 2026
  • 30 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £5609pp Now: £5384pp
View cruise
REF: HALV664
Cruise From:
Was £294pp Now: £279pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 23 Nov 2026
  • 3 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £79pp

Cruise From:
Was £294pp Now: £279pp
View cruise
REF: MSCMU20261123SSZSSZ
Cruise From:
Was £699pp Now: £674pp

12-Day Panama Canal with Costa Rica & Caribbean

Fort Lauderdale | Aruba | Cartagena | Colón | Cartagena | Puerto Limón | Celebration Key | Fort Lauderdale

  • 23 Nov 2026
  • 12 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £699pp Now: £674pp
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REF: PRINCESSB639
Cruise From:
Was £233pp Now: £226pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 23 Nov 2026
  • 4 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £233pp Now: £226pp
View cruise
REF: CARNIVALFN231120264
Fly Cruise From:
Was £2469pp Now: £2370pp

11 Nt Panama Canal & Southern Caribbean

Fort Lauderdale | Cartagena | Colón | Cartagena | Oranjestad | Willemstad | Kralendijk | Fort Lauderdale

  • 23 Nov 2026
  • 11 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £2469pp Now: £2370pp
View cruise
REF: CELEBAT11C025-231126
Fly Cruise From:
£1497pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 23 Nov 2026
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1497pp
View cruise
REF: RCIOV04X056-231126
Fly Cruise From:
£4099pp

Fort Lauderdale to Cartegena

Fort Lauderdale | Nassau | Samaná | San Juan (Puerto Rico) | Great Harbour | Oranjestad | Cartagena

  • 23 Nov 2026
  • 9 Nights
Fly Cruise From:
£4099pp
View cruise
REF: CRYSTALCSE-009-261123
Cruise From:
£7051pp

Fort Lauderdale to Puerto Caldera

Fort Lauderdale | Nassau | Samaná | San Juan (Puerto Rico) | Great Harbour | Oranjestad | Cartagena | Willemstad | Kralendijk | Oranjestad | Santa Marta | Fuerte Amador | Puerto Caldera

  • 23 Nov 2026
  • 19 Nights
Cruise From:
£7051pp
View cruise
REF: CRYSTALCSE-C19-261123
Cruise From:
£10548pp

Fort Lauderdale to San Diego

Fort Lauderdale | Nassau | Samaná | San Juan (Puerto Rico) | Great Harbour | Oranjestad | Cartagena | Willemstad | Kralendijk | Oranjestad | Santa Marta | Fuerte Amador | Puntarenas | Playa Flamingo | Acajutla | Zihuatanejo | Manzanillo | Puerto Vallarta | San Diego

  • 23 Nov 2026
  • 28 Nights
Cruise From:
£10548pp
View cruise
REF: CRYSTALCSE-C28-261123
Cruise From:
£1560pp

Fort Lauderdale to San Juan

Fort Lauderdale | Nassau | Samaná | San Juan (Puerto Rico)

  • 23 Nov 2026
  • 4 Nights
Cruise From:
£1560pp
View cruise
REF: CRYSTALCSE-S04-261123
Fly Cruise From:
Was £7990pp Now: £7670pp

Chilean Fjords & Scenic Shores

Valparaiso | Puerto Chacabuco | Chilean Fjords | Punta Arenas | Chilean Fjords | Garibaldi Fjord | Ushuaia

  • 23 Nov 2026
  • 12 Nights
Fly Cruise From:
Was £7990pp Now: £7670pp
View cruise
REF: VIKINGXOC261123
Cruise From:
Was £7668pp Now: £7437pp

Galápagos Islands - Nine of the Best Isles

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 24 Nov 2026
  • 15 Nights
Cruise From:
Was £7668pp Now: £7437pp
View cruise
REF: HX977913978324-2
Cruise From:
Was £5072pp Now: £4919pp

Galápagos Islands – Iconic Wildlife & Sublime Scenery | Western Route

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Lima | Fernandina Beach | Santa Cruz Island | Floreana Island | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 24 Nov 2026
  • 15 Nights
Cruise From:
Was £5072pp Now: £4919pp
View cruise
REF: HX977913977928-SCGAL2627W
Fly Cruise From:
£7329pp

Amazon & Caribbean Isles

Miami | Tortola | Saint John's | Castries | Scarborough | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Bridgetown | Roseau | Philipsburg | San Juan (Puerto Rico) | Nassau | Miami

  • 24 Nov 2026
  • 25 Nights
ENDS 30th June - Save up to 50%* - book before prices increase!
Choose between a FREE house beverage package OR up to $800 shore excursion credit
Fly Cruise From:
£7329pp
View cruise
REF: OCEANIAINS261124
Cruise From:
Was £31700pp Now: £30115pp

Puerto Williams to Puerto Williams

Puerto Williams | South Georgia Island | Elephant Island | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 24 Nov 2026
  • 15 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £31700pp Now: £30115pp
View cruise
REF: SILVERE4261124015
Cruise From:
Was £5399pp Now: £5183pp

27-Day Legendary Amazon Explorer

Fort Lauderdale | Sint Maarten | Fort-de-France | Bridgetown | Macapa | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Icoaraci | Devil's Island | Curaçao | Fort Lauderdale

  • 25 Nov 2026
  • 27 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £5399pp Now: £5183pp
View cruise
REF: HALV664A
Cruise From:
Was £6300pp Now: £4560pp

A Journey of Caribbean Charm & Spectacular Natural Beauty

Miami | Willemstad | Oranjestad | Santa Marta | Cartagena | Georgetown | Miami

  • 25 Nov 2026
  • 10 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
Was £6300pp Now: £4560pp
View cruise
REF: EXPLORAEX20261125MIAMIA
Cruise From:
£8320pp

An Extended Journey of Historic Echoes & Ocean Breezes

Miami | Willemstad | Oranjestad | Santa Marta | Cartagena | Georgetown | Miami | Cozumel | Costa Maya | Santo Tomás de Castilla | Belize City | Roatán Island | Miami

  • 25 Nov 2026
  • 18 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
£8320pp
View cruise
REF: EXPLORAEX20261125MIAMI1
Cruise From:
Was £17600pp Now: £16720pp

Puerto Williams to King George Island

Puerto Williams | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | King George Island

  • 25 Nov 2026
  • 9 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £17600pp Now: £16720pp
View cruise
REF: SILVERWI261125009
Fly Cruise From:
Was £15290pp Now: £14678pp

Antarctica & South Georgia Island

Ushuaia | West Point Island | Port Stanley | South Georgia Island | Antarctic Experience | Antarctica | Antarctic Experience | Ushuaia

  • 25 Nov 2026
  • 17 Nights
Fly Cruise From:
Was £15290pp Now: £14678pp
View cruise
REF: VIKINGXPO261125T

Mexican Riviera & Sea Of Cortez with San Diego Stay

Holiday prices from:
£1679pp

Mexican Riviera & Sea Of Cortez with San Diego Stay

San Diego | Cabo San Lucas | La Paz | Loreto | Mazatlán | Puerto Vallarta | San Diego

  • 26 Nov 2026
  • 13 Nights
  • Ten-night full-board cruise
  • Return flights with luggage allowance
  • Two night 4* hotel stay in San Diego
Holiday prices from:
£1679pp
View cruise
Cruise From:
Was £399pp Now: £379pp

South America 4 Nights From Santos

Santos | Buzios | Ilha Grande | Santos

  • 26 Nov 2026
  • 4 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £118pp

Cruise From:
Was £399pp Now: £379pp
View cruise
REF: MSCMU20261126SSZSSZ
Cruise From:
Was £9054pp Now: £8782pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 27 Nov 2026
  • 13 Nights
Cruise From:
Was £9054pp Now: £8782pp
View cruise
REF: HX978755978776
Cruise From:
Was £205pp Now: £198pp

3-Day Baja Mexico

Long Beach | Ensenada | Long Beach

  • 27 Nov 2026
  • 3 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £205pp Now: £198pp
View cruise
REF: CARNIVALFN271120263
Cruise From:
£319pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 27 Nov 2026
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £78pp

Cruise From:
£319pp
View cruise
REF: RCIOV03X041-271126
Cruise From:
£401pp

7 Night Ensenada, Cabo & Mazatlan

Los Angeles | Ensenada | Cabo San Lucas | Mazatlán | Los Angeles

  • 27 Nov 2026
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £115pp

Cruise From:
£401pp
View cruise
REF: RCIVY07X078-271126
Cruise From:
£1980pp

San Juan to Cartagena

San Juan (Puerto Rico) | Great Harbour | Oranjestad | Cartagena

  • 27 Nov 2026
  • 5 Nights
Cruise From:
£1980pp
View cruise
REF: CRYSTALCSE-S05-261127

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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