South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2496 cruises
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Fly Cruise From:
£1667pp

7 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Willemstad | Colón | Cartagena

  • 01 Nov 2026
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1667pp
View cruise
REF: RCIGR7IP222-011126
Cruise From:
Was £969pp Now: £899pp

World-wide 13 Nights From Tarragona

Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro

  • 02 Nov 2026
  • 13 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £969pp Now: £899pp
View cruise
REF: MSCDI20261102TARRIO
Cruise From:
Was £1019pp Now: £957pp

World-wide 14 Nights From Tarragona

Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro | Santos

  • 02 Nov 2026
  • 14 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1019pp Now: £957pp
View cruise
REF: MSCDI20261102TARSSZ
Cruise From:
Was £4849pp Now: £4699pp

Galápagos Islands - Nature and Wildlife Expedition Cruise | Northern Route

Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay

  • 02 Nov 2026
  • 6 Nights
Cruise From:
Was £4849pp Now: £4699pp
View cruise
REF: HX978271978288-SCGAL2627N
Fly Cruise From:
£1181pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 02 Nov 2026
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1181pp
View cruise
REF: RCIOV04X056-021126
Fly Cruise From:
Was £16409pp Now: £15499pp

Footsteps Of Columbus

Barcelona | Palma de Mallorca | Alicante | Cartagena | Málaga | Cádiz | Portimão | Lisbon | Arrecife | Las Palmas de Gran Canaria | Santa Cruz de La Palma | San Juan (Puerto Rico) | Nassau | Miami | Tortola | Saint John's | Castries | Scarborough | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Bridgetown | Roseau | Philipsburg | San Juan (Puerto Rico) | Nassau | Miami

  • 02 Nov 2026
  • 47 Nights
Choose between a FREE house beverage package OR up to $800 shore excursion credit
Fly Cruise From:
Was £16409pp Now: £15499pp
View cruise
REF: OCEANIAINS261102B
Cruise From:
Was £206pp Now: £199pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 03 Nov 2026
  • 5 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £206pp Now: £199pp
View cruise
REF: CARNIVALRD031120265
Fly Cruise From:
£15047pp

Chilean Fjords & The Glaciers of The Beagle Channel

Valparaiso | Niebla | Puerto Montt | Castro | Puerto Edén | PIO X Glacier | Punta Arenas | Chilean Fjords | Cape Horn | Buenos Aires | Ushuaia

  • 04 Nov 2026
  • 12 Nights
Fly Cruise From:
£15047pp
View cruise
REF: SCENIC201L041126-1
Fly Cruise From:
£20422pp

Treasures of South America with Chilean Fjords - Cruise & Land Journey

Valparaiso | Niebla | Puerto Montt | Castro | Puerto Edén | PIO X Glacier | Punta Arenas | Chilean Fjords | Cape Horn | Ushuaia | Buenos Aires | Iguazú Falls | Rio de Janeiro | Iguazú Falls | Rio de Janeiro

  • 04 Nov 2026
  • 21 Nights
Fly Cruise From:
£20422pp
View cruise
REF: SCENICOLA2041126-1
Cruise From:
Was £6055pp Now: £5873pp

In Darwin’s Footsteps (Eastern Route)

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 04 Nov 2026
  • 13 Nights
Cruise From:
Was £6055pp Now: £5873pp
View cruise
REF: HURT978711978732-2
Cruise From:
Was £11402pp Now: £11059pp

Galápagos Islands - Nine of the Best Isles Plus Machu Picchu

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 05 Nov 2026
  • 15 Nights
Cruise From:
Was £11402pp Now: £11059pp
View cruise
REF: HX977897978306
Fly Cruise From:
£1328pp

8 Nt Cabo Overnight, Mazatlan & Catalina

Los Angeles | Santa Catalina Island | Cabo San Lucas | Mazatlán | Los Angeles

  • 05 Nov 2026
  • 8 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1328pp
View cruise
REF: RCIVY08X011-051126
Fly Cruise From:
£1191pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 06 Nov 2026
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1191pp
View cruise
REF: RCIOV03X042-061126

Cruise & Stay

Mexican Riviera Voyage with Las Vegas & Santa Monica Stay

Holiday prices from:
£1615pp

Mexican Riviera Voyage with Las Vegas & Santa Monica Stay

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 07 Nov 2026
  • 16 Nights
  • Five-night 4* hotel stay in Las Vegas
  • Three-night 4* hotel stay in Santa Monica
  • Direct return and internal flights with luggage allowance
  • Seven-night full-board cruise
Holiday prices from:
£1615pp
View cruise
Cruise From:
Was £2069pp Now: £1944pp

World-wide 25 Nights From Southampton

Southampton | La Coruña | Cádiz | Málaga | Alicante | Palma de Mallorca | Marseille | Barcelona | Funchal | Arrecife | Las Palmas de Gran Canaria | Salvador de Bahia | Rio de Janeiro | Santos

  • 07 Nov 2026
  • 25 Nights
NEW 2028 sailings from the UK now on sale - secure the best cabins now
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2069pp Now: £1944pp
View cruise
REF: MSCVI20261107SOUSSZ
Cruise From:
Was £1939pp Now: £1822pp

World-wide 24 Nights From Southampton

Southampton | La Coruña | Cádiz | Málaga | Alicante | Palma de Mallorca | Marseille | Barcelona | Funchal | Arrecife | Las Palmas de Gran Canaria | Salvador de Bahia | Rio de Janeiro

  • 07 Nov 2026
  • 24 Nights
NEW 2028 sailings from the UK now on sale - secure the best cabins now
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1939pp Now: £1822pp
View cruise
REF: MSCVI20261107SOURIO
Cruise From:
Was £375pp Now: £363pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 07 Nov 2026
  • 8 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £375pp Now: £363pp
View cruise
REF: CARNIVALPO071120268
Cruise From:
Was £459pp Now: £442pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 07 Nov 2026
  • 7 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £459pp Now: £442pp
View cruise
REF: PRINCESSX639
Fly Cruise From:
£1747pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 07 Nov 2026
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1747pp
View cruise
REF: RCIGR07D502-071126
Cruise From:
Was £8150pp Now: £7742pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 07 Nov 2026
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £8150pp Now: £7742pp
View cruise
REF: SILVEROR261107007
Cruise From:
Was £20070pp Now: £19066pp

Puerto Williams to Puerto Williams

Puerto Williams | Saunders Island | West Point Island | Port Stanley | South Georgia Island | Elephant Island | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 07 Nov 2026
  • 18 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £20070pp Now: £19066pp
View cruise
REF: SILVERWI261107018
Cruise From:
£480pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 08 Nov 2026
  • 7 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £243pp

Cruise From:
£480pp
View cruise
REF: NCLENC-20261108-07-LAX-LAX
Fly Cruise From:
£1561pp

7 Night Ensenada, Cabo & Mazatlan Cruise

San Diego | Ensenada | Cabo San Lucas | Mazatlán | San Diego

  • 08 Nov 2026
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1561pp
View cruise
REF: RCISR07X071-081126
Cruise From:
Was £2129pp Now: £2043pp

12-Day Panama Canal Discovery: Costa Rica & Greater Antilles

Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Puerto Limón | Ocho Rios | Fort Lauderdale

  • 08 Nov 2026
  • 12 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2129pp Now: £2043pp
View cruise
REF: HALI676
Cruise From:
Was £3269pp Now: £3138pp

21-Day Panama Canal & Southern Caribbean Discovery

Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Puerto Limón | Ocho Rios | Fort Lauderdale | Bonaire | Curaçao | Half Moon Cay | Fort Lauderdale

  • 08 Nov 2026
  • 21 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £3269pp Now: £3138pp
View cruise
REF: HALI676A
Fly Cruise From:
£1625pp

6 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Willemstad | Colón

  • 08 Nov 2026
  • 6 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1625pp
View cruise
REF: RCIGR6IP219-081126
Cruise From:
Was £2102pp Now: £1975pp

World-wide 24 Nights From Marseille

Marseille | Livorno | Cagliari | Palermo | Valletta | Barcelona | Gibraltar | Casablanca | Las Palmas de Gran Canaria | Maceió | Salvador de Bahia | Rio de Janeiro | Montevideo | Buenos Aires

  • 09 Nov 2026
  • 24 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2102pp Now: £1975pp
View cruise
REF: MSCSP20261109MRSBUE
Fly Cruise From:
£1219pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 09 Nov 2026
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1219pp
View cruise
REF: RCIOV04X056-091126
Fly Cruise From:
Was £12214pp Now: £11599pp

Secrets Of The Amazon

Miami | Bridgetown | Port-of-Spain | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Saint George's | San Juan (Puerto Rico) | Miami

  • 09 Nov 2026
  • 22 Nights
Fly Cruise From:
Was £12214pp Now: £11599pp
View cruise
REF: REGENTMAR261109
Fly Cruise From:
Was £9809pp Now: £9269pp

Amazon & Tropical Isles

Lisbon | Arrecife | Las Palmas de Gran Canaria | Santa Cruz de La Palma | San Juan (Puerto Rico) | Nassau | Miami | Tortola | Saint John's | Castries | Scarborough | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Bridgetown | Roseau | Philipsburg | San Juan (Puerto Rico) | Nassau | Miami

  • 09 Nov 2026
  • 40 Nights
Choose between a FREE house beverage package OR up to $800 shore excursion credit
Fly Cruise From:
Was £9809pp Now: £9269pp
View cruise
REF: OCEANIAINS261109A

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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