South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2496 cruises
Per Person
Total Price
Cruise From:
Was £499pp Now: £481pp

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 17 Oct 2026
  • 7 Nights
Cruise From:
Was £499pp Now: £481pp
View cruise
REF: PRINCESSX636
Fly Cruise From:
£1571pp

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 17 Oct 2026
  • 7 Nights
Fly Cruise From:
£1571pp
View cruise
REF: RCIGR07D487-171026
Cruise From:
£579pp

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 17 Oct 2026
  • 7 Nights
Cruise From:
£579pp
View cruise
REF: VIRGINBR261017
Cruise From:
Was £12143pp Now: £11657pp

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 18 Oct 2026
  • 7 Nights
Cruise From:
Was £12143pp Now: £11657pp
View cruise
REF: CELEBFL07G058-181026
Cruise From:
£610pp

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 18 Oct 2026
  • 7 Nights
Cruise From:
£610pp
View cruise
REF: NCLENC-20261018-07-LAX-LAX
Cruise From:
£408pp

San Diego | Ensenada | Cabo San Lucas | La Paz | San Diego

  • 18 Oct 2026
  • 7 Nights
Cruise From:
£408pp
View cruise
REF: RCISR07X070-181026
Cruise From:
Was £2129pp Now: £2043pp

Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Puerto Limón | Grand Cayman | Fort Lauderdale

  • 18 Oct 2026
  • 12 Nights
Cruise From:
Was £2129pp Now: £2043pp
View cruise
REF: HALI672
Cruise From:
Was £3259pp Now: £3128pp

Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Puerto Limón | Grand Cayman | Fort Lauderdale | Cabo Rojo | Curaçao | Aruba | Half Moon Cay | Fort Lauderdale

  • 18 Oct 2026
  • 21 Nights
Cruise From:
Was £3259pp Now: £3128pp
View cruise
REF: HALI672A
Cruise From:
Was £264pp Now: £256pp

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 18 Oct 2026
  • 6 Nights
Cruise From:
Was £264pp Now: £256pp
View cruise
REF: CARNIVALPO181020266
Fly Cruise From:
£1613pp

Cartagena | Oranjestad | Willemstad | Colón | Cartagena

  • 18 Oct 2026
  • 7 Nights
Fly Cruise From:
£1613pp
View cruise
REF: RCIGR7IP220-181026
Cruise From:
Was £4626pp Now: £4487pp

Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay

  • 19 Oct 2026
  • 6 Nights
Cruise From:
Was £4626pp Now: £4487pp
REF: HX978253978270-SCGAL2627N
Cruise From:
£288pp

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 19 Oct 2026
  • 4 Nights
Cruise From:
£288pp
View cruise
REF: RCIOV04X055-191026
Cruise From:
Was £1549pp Now: £1487pp

San Diego | Manzanillo | Puerto Vallarta | Mazatlán | La Paz | Loreto | Cabo San Lucas | San Diego

  • 20 Oct 2026
  • 11 Nights
Cruise From:
Was £1549pp Now: £1487pp
View cruise
REF: HALK673
Cruise From:
Was £9900pp Now: £9399pp

Puerto Williams | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | King George Island

  • 20 Oct 2026
  • 9 Nights
Cruise From:
Was £9900pp Now: £9399pp
REF: SILVERWI261020009
Cruise From:
Was £5752pp Now: £5579pp

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 21 Oct 2026
  • 13 Nights
Cruise From:
Was £5752pp Now: £5579pp
REF: HURT978689978710-2
Fly Cruise From:
£23635pp

Lima | Machu Picchu | Cuzco | Machu Picchu | Cuzco | Santiago | Valparaiso | Santiago | Niebla | Puerto Montt | Castro | Puerto Edén | PIO X Glacier | Punta Arenas | Chilean Fjords | Cape Horn | Buenos Aires | Ushuaia

  • 22 Oct 2026
  • 25 Nights
Fly Cruise From:
£23635pp
REF: SCENICOLZ2221026-1
Cruise From:
Was £10585pp Now: £10267pp

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Las Bachas | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 22 Oct 2026
  • 15 Nights
Cruise From:
Was £10585pp Now: £10267pp
REF: HX977881978288
Cruise From:
Was £1487pp Now: £1397pp

Miami | Kralendijk | Oranjestad | Willemstad | Cabo Rojo | Ocho Rios | Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 22 Oct 2026
  • 21 Nights
Cruise From:
Was £1487pp Now: £1397pp
View cruise
REF: MSCPO20261022MIAMI1
Fly Cruise From:
£1536pp

Los Angeles | Santa Catalina Island | Cabo San Lucas | Mazatlán | Los Angeles

  • 22 Oct 2026
  • 8 Nights
Fly Cruise From:
£1536pp
View cruise
REF: RCIVY08X011-221026
Cruise From:
£267pp

Los Angeles | Ensenada | Los Angeles

  • 23 Oct 2026
  • 3 Nights

Interest free Monthly Payments from JUST £112pp

Cruise From:
£267pp
View cruise
REF: RCIOV03X040-231026
Fly Cruise From:
Was £20649pp Now: £19513pp

Venice | Rijeka | Split | Kotor | Igoumenítsa | Gallipoli | Catania | Naples | Civitavecchia | Barcelona | Palma de Mallorca | Alicante | Cartagena | Málaga | Cádiz | Portimão | Lisbon | Arrecife | Las Palmas de Gran Canaria | Santa Cruz de La Palma | San Juan (Puerto Rico) | Nassau | Miami | Tortola | Saint John's | Castries | Scarborough | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Bridgetown | Roseau | Philipsburg | San Juan (Puerto Rico) | Nassau | Miami

  • 23 Oct 2026
  • 57 Nights
Fly Cruise From:
Was £20649pp Now: £19513pp
REF: OCEANIAINS261023C
Cruise From:
Was £375pp Now: £363pp

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 24 Oct 2026
  • 8 Nights
Cruise From:
Was £375pp Now: £363pp
View cruise
REF: CARNIVALPO241020268
Cruise From:
Was £459pp Now: £442pp

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 24 Oct 2026
  • 7 Nights
Cruise From:
Was £459pp Now: £442pp
View cruise
REF: PRINCESSX637
Fly Cruise From:
£1848pp

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 24 Oct 2026
  • 7 Nights
Fly Cruise From:
£1848pp
View cruise
REF: RCIGR07D489-241026
Cruise From:
Was £7650pp Now: £7267pp

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 24 Oct 2026
  • 7 Nights
Cruise From:
Was £7650pp Now: £7267pp
REF: SILVEROR261024007
Cruise From:
Was £730pp Now: £708pp

Los Angeles | Santa Catalina Island | San Diego | Ensenada | Los Angeles

  • 24 Oct 2026
  • 5 Nights
Cruise From:
Was £730pp Now: £708pp
View cruise
REF: VIRGINBR261024
Cruise From:
Was £5944pp Now: £5699pp

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 25 Oct 2026
  • 7 Nights
Cruise From:
Was £5944pp Now: £5699pp
View cruise
REF: CELEBFL07G057-251026
Cruise From:
Was £167pp Now: £161pp

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 25 Oct 2026
  • 4 Nights
Cruise From:
Was £167pp Now: £161pp
View cruise
REF: CARNIVALRD251020264
Cruise From:
£480pp

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 25 Oct 2026
  • 7 Nights
Cruise From:
£480pp
View cruise
REF: NCLENC-20261025-07-LAX-LAX
Cruise From:
£442pp

San Diego | La Paz | Cabo San Lucas | Ensenada | San Diego

  • 25 Oct 2026
  • 7 Nights
Cruise From:
£442pp
View cruise
REF: RCISR07X069-251026

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

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