South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2496 cruises
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Fly Cruise From:
£1749pp

7 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Willemstad | Colón | Cartagena

  • 25 Oct 2026
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1749pp
View cruise
REF: RCIGR7IP221-251026
Fly Cruise From:
Was £9990pp Now: £9590pp

Panama Canal & the Americas

New York | San Salvador Island | Inagua | Port Antonio | Fuerte Amador | Callao | Iquique | Valparaiso

  • 25 Oct 2026
  • 19 Nights
Fly Cruise From:
Was £9990pp Now: £9590pp
View cruise
REF: VIKINGXPO261025
Fly Cruise From:
£6379pp

Wellness Retreat - Panama City to Valparaiso

Panama City | Valparaiso

  • 26 Oct 2026
  • 9 Nights
Fly Cruise From:
£6379pp
View cruise
REF: SCENIC801R261026-1
Cruise From:
Was £2309pp Now: £2170pp

World-wide 21 Nights From Kusadasi

Kusadasi | Marmaris | Naples | Civitavecchia | Genoa | Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro | Santos

  • 26 Oct 2026
  • 21 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Reduced late deals, book now! Limited cabins remaining
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2309pp Now: £2170pp
View cruise
REF: MSCDI20261026KUSSSZ
Cruise From:
£275pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 26 Oct 2026
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £109pp

Cruise From:
£275pp
View cruise
REF: RCIOV04X055-261026
Fly Cruise From:
Was £9112pp Now: £8838pp

Galápagos Islands - Nine of the Best Isles

Lima | Puerto Egas | Buccaneer Cove | Bartolome Island | Rabida Island | El Barranco | Baltra Island | Darwin Bay | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 27 Oct 2026
  • 15 Nights
Fly Cruise From:
Was £9112pp Now: £8838pp
View cruise
REF: HURT977881978288-2
Cruise From:
Was £4849pp Now: £4699pp

Galápagos Islands – Iconic Wildlife & Sublime Scenery | Western Route

Lima | Baltra Island | Dragon Hill | Punta Vicente Roca | Puerto Ayora | Fernandina Island | Champion Island | Post Office Bay | Punta Cormorant | Baltra Island | Lima | Fernandina Beach | Santa Cruz Island | Floreana Island | Baltra Island | Santiago Island | Rabida Island | Genovesa Island | Quito

  • 27 Oct 2026
  • 15 Nights
Cruise From:
Was £4849pp Now: £4699pp
View cruise
REF: HX977881977896-SCGAL2627W
Cruise From:
Was £1569pp Now: £1474pp

World-wide 17 Nights From Naples

Naples | Civitavecchia | Genoa | Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro

  • 29 Oct 2026
  • 17 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Reduced late deals, book now! Limited cabins remaining
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1569pp Now: £1474pp
View cruise
REF: MSCDI20261029NAPRIO
Cruise From:
Was £1369pp Now: £1286pp

World-wide 18 Nights From Naples

Naples | Civitavecchia | Genoa | Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro | Santos

  • 29 Oct 2026
  • 18 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Reduced late deals, book now! Limited cabins remaining
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1369pp Now: £1286pp
View cruise
REF: MSCDI20261029NAPSSZ
Cruise From:
Was £213pp Now: £206pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 29 Oct 2026
  • 5 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £213pp Now: £206pp
View cruise
REF: CARNIVALRD291020265
Cruise From:
Was £1276pp Now: £1237pp

Panama Canal: LA to Miami Halloween

Los Angeles | Cabo San Lucas | Puerto Quetzal | Puntarenas | Panama City | Cartagena | Miami

  • 29 Oct 2026
  • 17 Nights
Receive FREE on-board credit on selected sailings
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1276pp Now: £1237pp
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REF: VIRGINBR261029
Cruise From:
Was £12700pp Now: £12065pp

King George Island to Puerto Williams

King George Island | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 29 Oct 2026
  • 9 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £12700pp Now: £12065pp
View cruise
REF: SILVERWI261029009
Cruise From:
Was £9357pp Now: £9076pp

Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu

Lima | Baltra Island | Mosquera Island | Punta Pitt | Puerto Baquerizo Moreno | South Plaza Island | Santa Fé Island | Puerto Ayora | Punta Suarez | Gardner Bay | North Seymour Island | El Edén Island | Baltra Island | Santa Fé Island | Santa Cruz Island | Espanola Island | North Seymour Island | Quito

  • 30 Oct 2026
  • 13 Nights
Cruise From:
Was £9357pp Now: £9076pp
View cruise
REF: HX978711978732
Cruise From:
Was £1019pp Now: £957pp

World-wide 16 Nights From Civitavecchia

Civitavecchia | Genoa | Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro

  • 30 Oct 2026
  • 16 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Reduced late deals, book now! Limited cabins remaining
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1019pp Now: £957pp
View cruise
REF: MSCDI20261030CVVRIO
Cruise From:
Was £889pp Now: £835pp

World-wide 13 Nights From Civitavecchia

Civitavecchia | Genoa | Tarragona | Santa Cruz de Tenerife | Salvador de Bahia

  • 30 Oct 2026
  • 13 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Reduced late deals, book now! Limited cabins remaining
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £889pp Now: £835pp
View cruise
REF: MSCDI20261030CVVSSA
Cruise From:
Was £1069pp Now: £999pp

World-wide 17 Nights From Civitavecchia

Civitavecchia | Genoa | Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro | Santos

  • 30 Oct 2026
  • 17 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Reduced late deals, book now! Limited cabins remaining
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1069pp Now: £999pp
View cruise
REF: MSCDI20261030CVVSSZ
Cruise From:
Was £739pp Now: £713pp

12-Day Panama Canal with Costa Rica & Caribbean

Fort Lauderdale | Curaçao | Cartagena | Colón | Cartagena | Puerto Limón | Celebration Key | Fort Lauderdale

  • 30 Oct 2026
  • 12 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £739pp Now: £713pp
View cruise
REF: PRINCESSB637
Cruise From:
£246pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 30 Oct 2026
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £76pp

Cruise From:
£246pp
View cruise
REF: RCIOV03X041-301026
Cruise From:
£313pp

6 Night Cabo Overnight & Ensenada

Los Angeles | Cabo San Lucas | Ensenada | Los Angeles

  • 30 Oct 2026
  • 6 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £128pp

Cruise From:
£313pp
View cruise
REF: RCIVY06X022-301026
Cruise From:
Was £3259pp Now: £3128pp

21-Day Southern Caribbean & Panama Canal: Abc Islands

Fort Lauderdale | Cabo Rojo | Curaçao | Aruba | Half Moon Cay | Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Cartagena | Puerto Limón | Ocho Rios | Fort Lauderdale

  • 30 Oct 2026
  • 21 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £3259pp Now: £3128pp
View cruise
REF: HALI675A
Cruise From:
Was £1109pp Now: £1042pp

World-wide 16 Nights From Genoa

Genoa | Tarragona | Santa Cruz de Tenerife | Salvador de Bahia | Rio de Janeiro | Santos

  • 31 Oct 2026
  • 16 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1109pp Now: £1042pp
View cruise
REF: MSCDI20261031GOASSZ
Cruise From:
Was £499pp Now: £481pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 31 Oct 2026
  • 7 Nights
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £499pp Now: £481pp
View cruise
REF: PRINCESSX638
Fly Cruise From:
£1667pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 31 Oct 2026
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1667pp
View cruise
REF: RCIGR07D490-311026
Cruise From:
Was £15390pp Now: £14620pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 31 Oct 2026
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £15390pp Now: £14620pp
View cruise
REF: SILVEROR261031007
Cruise From:
Was £902pp Now: £847pp

Caribbean 11 Nights From Miami, Florida

Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 01 Nov 2026
  • 11 Nights
Book now with a LOW £50pp deposit! - ends 30th June
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £902pp Now: £847pp
View cruise
REF: MSCPO20261101MIAMIA
Cruise From:
Was £1567pp Now: £1472pp

Caribbean 21 Nights From Miami, Florida

Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami | Charlotte Amalie | Basseterre | Philipsburg | Saint John's | San Juan (Puerto Rico) | Puerto Plata | Miami

  • 01 Nov 2026
  • 21 Nights
Book now with a LOW £50pp deposit! - ends 30th June
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1567pp Now: £1472pp
View cruise
REF: MSCPO20261101MIAMI1
Cruise From:
Was £6224pp Now: £5975pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 01 Nov 2026
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £6224pp Now: £5975pp
View cruise
REF: CELEBFL07G058-011126
Cruise From:
£465pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 01 Nov 2026
  • 7 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
£465pp
View cruise
REF: NCLENC-20261101-07-LAX-LAX
Fly Cruise From:
£1563pp

7 Night Ensenada, Cabo & Mazatlan Cruise

San Diego | Ensenada | Cabo San Lucas | Mazatlán | San Diego

  • 01 Nov 2026
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1563pp
View cruise
REF: RCISR07X071-011126
Cruise From:
Was £242pp Now: £234pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 01 Nov 2026
  • 6 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £242pp Now: £234pp
View cruise
REF: CARNIVALPO011120266

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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