South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2480 cruises
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Cruise From:
Was £10440pp Now: £9918pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 30 Jan 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10440pp Now: £9918pp
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REF: SILVEROR270130007
Cruise From:
Was £2509pp Now: £2399pp

15-Day Panama Canal

San Diego | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Fuerte Amador | Cartagena | Half Moon Cay | Miami

  • 30 Jan 2027
  • 15 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2509pp Now: £2399pp
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REF: HALU715
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Itajai

Itajai | Ilhabela | Rio de Janeiro | Buzios | Ilha Grande | Paranaguá | Itajai

  • 31 Jan 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £119pp

Cruise From:
Was £664pp Now: £624pp
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REF: MSCMU20270131ITJITJ
Cruise From:
Was £714pp Now: £671pp

South America 7 Nights From Santos

Santos | Camboriú | Punta del Este | Buenos Aires | Santos

  • 31 Jan 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £129pp

Cruise From:
Was £714pp Now: £671pp
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REF: MSCSV20270131SSZSSZ
Cruise From:
Was £10098pp Now: £9694pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 31 Jan 2027
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £10098pp Now: £9694pp
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REF: CELEBFL07G059-310127
Cruise From:
Was £208pp Now: £201pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 31 Jan 2027
  • 4 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £208pp Now: £201pp
View cruise
REF: CARNIVALRD310120274
Cruise From:
£475pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 31 Jan 2027
  • 7 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £89pp

Cruise From:
£475pp
View cruise
REF: NCLENC-20270131-07-LAX-LAX
Fly Cruise From:
£1838pp

7 Night Southern Caribbean Cruise

Cartagena | Willemstad | Oranjestad | Kralendijk | Colón | Cartagena

  • 31 Jan 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1838pp
View cruise
REF: RCIGR7IP229-310127
Fly Cruise From:
Was £5187pp Now: £4979pp

22-Day South America & Antarctica

Buenos Aires | Montevideo | Puerto Madryn | Port Stanley | Antarctic Experience | Ushuaia | Punta Arenas | Puerto Chacabuco | Puerto Montt | San Antonio

  • 01 Feb 2027
  • 22 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £5187pp Now: £4979pp
View cruise
REF: HALO711
Cruise From:
Was £15597pp Now: £13881pp

10-Day The Great White Continent

Buenos Aires | Ushuaia | Antarctic Experience | Buenos Aires | Ushuaia

  • 01 Feb 2027
  • 11 Nights
Receive up to $1,000 onboard spend per couple
Cruise From:
Was £15597pp Now: £13881pp
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REF: SBNP714
Cruise From:
Was £1481pp Now: £1392pp

South America 9 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Buzios | Ilhabela | Camboriú | Punta del Este | Buenos Aires

  • 01 Feb 2027
  • 9 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1481pp Now: £1392pp
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REF: MSCSP20270201BUEBUE
Cruise From:
Was £704pp Now: £661pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 01 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £126pp

Cruise From:
Was £704pp Now: £661pp
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REF: MSCSV20270201CBUCBU
Cruise From:
Was £449pp Now: £426pp

South America 4 Nights From Santos

Santos | Buzios | Ilha Grande | Santos

  • 01 Feb 2027
  • 4 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £74pp

Cruise From:
Was £449pp Now: £426pp
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REF: MSCDI20270201SSZSSZ
Cruise From:
Was £1001pp Now: £940pp

South America 7 Nights From Salvador de Bahia

Salvador de Bahia | Maceió | Santos | Buzios | Salvador de Bahia

  • 02 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £187pp

Cruise From:
Was £1001pp Now: £940pp
View cruise
REF: MSCVI20270202SSASSA
Cruise From:
Was £664pp Now: £624pp

South America 7 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Ilha Grande | Paranaguá | Itajai | Ilhabela | Rio de Janeiro

  • 02 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £117pp

Cruise From:
Was £664pp Now: £624pp
View cruise
REF: MSCMU20270202RIORIO
Fly Cruise From:
Was £12084pp Now: £7479pp

Colossal Coastlines

Buenos Aires | Puerto Madryn | Punta Arenas | Ushuaia | Port Stanley | Punta del Este | Montevideo | Buenos Aires

  • 02 Feb 2027
  • 18 Nights
Exquisite Escapes Sale - Save up to 50%* - Offers end 30 June
Fly Cruise From:
Was £12084pp Now: £7479pp
View cruise
REF: REGENTMAR270202
Cruise From:
Was £15480pp Now: £14699pp

King George Island to Puerto Williams

King George Island | Antarctic Sound | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 02 Feb 2027
  • 9 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £15480pp Now: £14699pp
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REF: SILVERWI270202009
Cruise From:
Was £13320pp Now: £12654pp

Punta Arenas to Puerto Williams

Punta Arenas | South Shetland Islands | Antarctic Peninsula | South Shetland Islands | Puerto Williams

  • 02 Feb 2027
  • 10 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £13320pp Now: £12654pp
View cruise
REF: SILVERE4270202010
Cruise From:
Was £1097pp Now: £1031pp

South America 7 Nights From Maceió

Maceió | Santos | Buzios | Salvador de Bahia | Maceió

  • 03 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £206pp

Cruise From:
Was £1097pp Now: £1031pp
View cruise
REF: MSCVI20270203MCZMCZ
Cruise From:
Was £889pp Now: £857pp

12-Day Panama Canal with Costa Rica & Caribbean

Fort Lauderdale | Aruba | Cartagena | Colón | Cartagena | Puerto Limón | Grand Cayman | Fort Lauderdale

  • 03 Feb 2027
  • 12 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £202pp

Cruise From:
Was £889pp Now: £857pp
View cruise
REF: PRINCESSB704
Cruise From:
£420pp

5 Night Cabo Overnight Cruise

Los Angeles | Cabo San Lucas | Los Angeles

  • 03 Feb 2027
  • 5 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £63pp

Cruise From:
£420pp
View cruise
REF: RCIVY05X023-030227
Cruise From:
Was £1064pp Now: £999pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Punta del Este | Buenos Aires

  • 04 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £198pp

Cruise From:
Was £1064pp Now: £999pp
View cruise
REF: MSCSV20270204BUEBUE
Cruise From:
Was £1086pp Now: £1020pp

South America 9 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Ilhabela | Camboriú | Punta del Este | Buenos Aires | Rio de Janeiro

  • 04 Feb 2027
  • 9 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £202pp

Cruise From:
Was £1086pp Now: £1020pp
View cruise
REF: MSCSP20270204RIORIO
Cruise From:
Was £209pp Now: £202pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 04 Feb 2027
  • 5 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £209pp Now: £202pp
View cruise
REF: CARNIVALRD040220275
Cruise From:
£266pp

3 Night Ensenada Cruise

San Diego | Ensenada | San Diego

  • 04 Feb 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £27pp

Cruise From:
£266pp
View cruise
REF: RCISR03X043-040227
Cruise From:
Was £629pp Now: £597pp

South America 4 Nights From Santos

Santos | Ilha Grande | Buzios | Santos

  • 05 Feb 2027
  • 4 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £109pp

Cruise From:
Was £629pp Now: £597pp
View cruise
REF: MSCDI20270205SSZSSZ
Cruise From:
£272pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 05 Feb 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £28pp

Cruise From:
£272pp
View cruise
REF: RCIOV03X042-050227
Fly Cruise From:
Was £12990pp Now: £12470pp

Antarctic Explorer

Ushuaia | Antarctic Experience | Antarctica | Antarctic Experience | Antarctica | Ushuaia

  • 05 Feb 2027
  • 11 Nights
Fly Cruise From:
Was £12990pp Now: £12470pp
View cruise
REF: VIKINGXPO270205T
Cruise From:
£7170pp

A Journey of Amazon Exploration & Cultural Discovery

San Juan (Puerto Rico) | Gustavia | Saint Pierre | Bridgetown | Port-of-Spain | Macapa | Santarém | Boca de Valeria | Manaus

  • 05 Feb 2027
  • 12 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
£7170pp
View cruise
REF: EXPLORAEX20270205SJUMAO
Cruise From:
£15675pp

An Extended Journey into Island Elegance & Mysteries of the Amazon

San Juan (Puerto Rico) | Gustavia | Saint Pierre | Bridgetown | Port-of-Spain | Macapa | Santarém | Boca de Valeria | Manaus | Parintins | Alter do Chão | Macapa | Devil's Island | Port Elizabeth | Bridgetown | Castries | Gustavia | Basseterre | San Juan (Puerto Rico)

  • 05 Feb 2027
  • 24 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
£15675pp
View cruise
REF: EXPLORAEX20270205SJUSJU

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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