South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2480 cruises
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Fly Cruise From:
£7089pp

Southern Fjords & Glaciers

Valparaiso | Puerto Montt | Castro | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Port Stanley | Puerto Madryn | Buenos Aires

  • 14 Feb 2027
  • 21 Nights
Choose between a FREE house beverage package OR up to $800 shore excursion credit
Fly Cruise From:
£7089pp
View cruise
REF: OCEANIAINS270214
Fly Cruise From:
Was £9579pp Now: £9052pp

Captain Drake's Crossroads

Valparaiso | Puerto Montt | Castro | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Port Stanley | Puerto Madryn | Buenos Aires | Montevideo | Punta del Este | Rio Grande | Florianópolis | Itajai | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro

  • 14 Feb 2027
  • 33 Nights
Choose between a FREE house beverage package OR up to $800 shore excursion credit
Fly Cruise From:
Was £9579pp Now: £9052pp
View cruise
REF: OCEANIAINS270214A
Fly Cruise From:
Was £13879pp Now: £13115pp

Epic Antarctic & Amazon

Valparaiso | Puerto Montt | Castro | Puerto Chacabuco | Laguna San Rafael National Park | Punta Arenas | Ushuaia | Port Stanley | Puerto Madryn | Buenos Aires | Montevideo | Punta del Este | Rio Grande | Florianópolis | Itajai | Santos | Parati | Ilha Grande | Buzios | Rio de Janeiro | Alter do Chão | Boca de Valeria | Manaus | Parintins | Santarém | Bridgetown | Saint John's | Charlotte Amalie | Miami

  • 14 Feb 2027
  • 54 Nights
Choose between a FREE house beverage package OR up to $800 shore excursion credit
Fly Cruise From:
Was £13879pp Now: £13115pp
View cruise
REF: OCEANIAINS270214B
Fly Cruise From:
£1979pp

7 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Kralendijk | Colón | Cartagena

  • 14 Feb 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1979pp
View cruise
REF: RCIGR7IP230-140227
Cruise From:
Was £724pp Now: £680pp

South America 7 Nights From Camboriú

Camboriú | Punta del Este | Buenos Aires | Santos | Camboriú

  • 15 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £119pp

Cruise From:
Was £724pp Now: £680pp
View cruise
REF: MSCSV20270215CBUCBU
Cruise From:
Was £479pp Now: £455pp

South America 4 Nights From Santos

Santos | Buzios | Ilha Grande | Santos

  • 15 Feb 2027
  • 4 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £73pp

Cruise From:
Was £479pp Now: £455pp
View cruise
REF: MSCDI20270215SSZSSZ
Cruise From:
Was £809pp Now: £780pp

12-Day Panama Canal with Costa Rica & Caribbean

Fort Lauderdale | Aruba | Cartagena | Colón | Cartagena | Puerto Limón | Grand Cayman | Fort Lauderdale

  • 15 Feb 2027
  • 12 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £165pp

Cruise From:
Was £809pp Now: £780pp
View cruise
REF: PRINCESSB705
Cruise From:
£336pp

4 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 15 Feb 2027
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £40pp

Cruise From:
£336pp
View cruise
REF: RCIVY04X062-150227
Cruise From:
Was £845pp Now: £794pp

South America 7 Nights From Salvador de Bahia

Salvador de Bahia | Maceió | Santos | Buzios | Salvador de Bahia

  • 16 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £141pp

Cruise From:
Was £845pp Now: £794pp
View cruise
REF: MSCVI20270216SSASSA
Cruise From:
Was £654pp Now: £614pp

South America 7 Nights From Rio de Janeiro

Rio de Janeiro | Buzios | Ilha Grande | Paranaguá | Itajai | Ilhabela | Rio de Janeiro

  • 16 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £104pp

Cruise From:
Was £654pp Now: £614pp
View cruise
REF: MSCMU20270216RIORIO
Fly Cruise From:
Was £12990pp Now: £12470pp

Antarctic Explorer

Ushuaia | Antarctic Experience | Antarctica | Antarctic Experience | Antarctica | Ushuaia

  • 16 Feb 2027
  • 11 Nights
Fly Cruise From:
Was £12990pp Now: £12470pp
View cruise
REF: VIKINGXPO270216T
Cruise From:
£6579pp

Antarctica & Chilean Fjords Cruise: Buenos Aires, Ushuaia & Santiago

Buenos Aires | Montevideo | Punta del Este | Port Stanley | Half Moon Island | Deception Island | Paradise Harbour | Melchior Islands | Paradise Harbour | Ushuaia | Punta Arenas | Chilean Fjords | Puerto Chacabuco | Puerto Montt | San Antonio

  • 17 Feb 2027
  • 21 Nights
Azamara Always Included: Beer, Wine & Spirits ALL day & Night | Gratuities | Variety of dining venues & 24-hour room service | Unlimited self-serve laundry | Signature AzAmazing Evenings
Cruise From:
£6579pp
View cruise
REF: AZJR270217-021
Cruise From:
Was £12629pp Now: £12123pp

Buenos Aires to Miami Grand Voyage

Buenos Aires | Montevideo | Punta del Este | Port Stanley | Half Moon Island | Deception Island | Paradise Harbour | Melchior Islands | Paradise Harbour | Ushuaia | Punta Arenas | Chilean Fjords | Puerto Chacabuco | Puerto Montt | San Antonio | Coquimbo | Iquique | Arica | Pisco | Callao | Fuerte Amador | Puerto Limón | San Andrés Island | Cozumel | Miami

  • 17 Feb 2027
  • 40 Nights
FLASH SALE - Save up to 20% - ends 30th June
Azamara Always Included: Beer, Wine & Spirits ALL day & Night | Gratuities | Variety of dining venues & 24-hour room service | Unlimited self-serve laundry | Signature AzAmazing Evenings
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £12629pp Now: £12123pp
View cruise
REF: AZJR270217-040
Fly Cruise From:
£18943pp

Antarctica in Depth

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Buenos Aires | Ushuaia

  • 17 Feb 2027
  • 12 Nights
Fly Cruise From:
£18943pp
View cruise
REF: SCENIC101S170227-1
Fly Cruise From:
£29495pp

Ultimate Antarctica & the Fjords of Southern Chile

Buenos Aires | Ushuaia | Antarctic Peninsula | Ushuaia | Cape Horn | Chilean Fjords | Aguila Glacier | Tuckers Islets | Magdalena Island | Admiralty Bay | Punta Arenas | Isla Pinguino | Punta Piramides | Montevideo | Buenos Aires

  • 17 Feb 2027
  • 28 Nights
Fly Cruise From:
£29495pp
View cruise
REF: SCENIC702L170227-2
Cruise From:
Was £833pp Now: £783pp

South America 7 Nights From Maceió

Maceió | Santos | Buzios | Salvador de Bahia | Maceió

  • 17 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £138pp

Cruise From:
Was £833pp Now: £783pp
View cruise
REF: MSCVI20270217MCZMCZ
Cruise From:
Was £1555pp Now: £1523pp

Panama Canal: Mexico, Jamaica & Costa Rica

Miami | Georgetown | Falmouth | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 17 Feb 2027
  • 12 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1555pp Now: £1523pp
View cruise
REF: NCLSUN-20270217-12-MIA-MIA
Cruise From:
£8700pp

A Journey from Amazon Adventures to Caribbean Charms

Manaus | Parintins | Alter do Chão | Macapa | Devil's Island | Port Elizabeth | Bridgetown | Castries | Gustavia | Basseterre | San Juan (Puerto Rico)

  • 17 Feb 2027
  • 12 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
£8700pp
View cruise
REF: EXPLORAEX20270217MAOSJU
Cruise From:
£9975pp

An Extended Journey of Rainforest Wonders & Ocean Serenity

Manaus | Parintins | Alter do Chão | Macapa | Devil's Island | Port Elizabeth | Bridgetown | Castries | Gustavia | Basseterre | San Juan (Puerto Rico) | Saint John's | Road Bay | Spanish Town | Grand Turk Island | Miami

  • 17 Feb 2027
  • 19 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
£9975pp
View cruise
REF: EXPLORAEX20270217MAOMIA
Cruise From:
Was £10800pp Now: £10260pp

Buenos Aires to Valparaiso

Buenos Aires | Puerto Madryn | Port Stanley | Ushuaia | Punta Arenas | Chilean Fjords | Puerto Montt | Valparaiso

  • 17 Feb 2027
  • 16 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10800pp Now: £10260pp
View cruise
REF: SILVERSN270217016
Cruise From:
Was £1064pp Now: £999pp

South America 7 Nights From Buenos Aires

Buenos Aires | Santos | Camboriú | Punta del Este | Buenos Aires

  • 18 Feb 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £180pp

Cruise From:
Was £1064pp Now: £999pp
View cruise
REF: MSCSV20270218BUEBUE
Cruise From:
£265pp

3 Night Ensenada Cruise

San Diego | Ensenada | San Diego

  • 18 Feb 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £24pp

Cruise From:
£265pp
View cruise
REF: RCISR03X043-180227
Cruise From:
Was £1190pp Now: £1118pp

South America 8 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires

  • 19 Feb 2027
  • 8 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £202pp

Cruise From:
Was £1190pp Now: £1118pp
View cruise
REF: MSCSP20270219BUEBUE
Cruise From:
Was £474pp Now: £450pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 19 Feb 2027
  • 3 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £70pp

Cruise From:
Was £474pp Now: £450pp
View cruise
REF: MSCDI20270219SSZSSZ
Cruise From:
£262pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 19 Feb 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £24pp

Cruise From:
£262pp
View cruise
REF: RCIOV03X041-190227
Cruise From:
£393pp

7 Night Ensenada, Cabo & Mazatlan

Los Angeles | Ensenada | Cabo San Lucas | Mazatlán | Los Angeles

  • 19 Feb 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £51pp

Cruise From:
£393pp
View cruise
REF: RCIVY07X078-190227
Cruise From:
Was £3749pp Now: £3599pp

21-Day Southern Caribbean & Panama Canal: Abc Islands

Fort Lauderdale | Bonaire | Curaçao | Aruba | Half Moon Cay | Fort Lauderdale | Half Moon Cay | Aruba | Cartagena | Colón | Gatun Lake | Cartagena | Puerto Limón | Grand Cayman | Fort Lauderdale

  • 19 Feb 2027
  • 21 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £3749pp Now: £3599pp
View cruise
REF: HALI718A
Cruise From:
Was £14597pp Now: £12991pp

10-Day The Great White Continent

Buenos Aires | Ushuaia | Antarctic Experience | Buenos Aires | Ushuaia

  • 20 Feb 2027
  • 11 Nights
Receive up to $1,000 onboard spend per couple
Cruise From:
Was £14597pp Now: £12991pp
View cruise
REF: SBNV719

Cruise & Stay

The Ultimate Argentinian Escape

Holiday prices from:
£4619pp

The Ultimate Argentinian Escape

Buenos Aires | Montevideo | Port Stanley | Ushuaia | Punta Arenas | Puerto Madryn | Punta del Este | Buenos Aires

  • 20 Feb 2027
  • 22 Nights
  • Hotel stays in Buenos Aires and Iguazu
  • Return and internal flights with luggage allowance
  • Private overseas transfers
  • 14-night full-board cruise
Holiday prices from:
£4619pp
View cruise

Cruise & Stay

Chilean Fjords & Glaciers with Santiago & Buenos Aires Stay

Holiday prices from:
£3039pp

Chilean Fjords & Glaciers with Santiago & Buenos Aires Stay

San Antonio | Puerto Montt | Puerto Chacabuco | PIO X Glacier | Punta Arenas | Ushuaia | Port Stanley | Montevideo | Buenos Aires

  • 20 Feb 2027
  • 20 Nights
  • Return flights with luggage allowance
  • Private overseas transfers
  • 4* hotel stays in Santiago and Buenos Aires
  • 14-night full-board cruise
Holiday prices from:
£3039pp
View cruise

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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