South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2484 cruises
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Cruise From:
Was £1721pp Now: £1617pp

South America 8 Nights From Rio de Janeiro

Rio de Janeiro | Ilhabela | Camboriú | Punta del Este | Buenos Aires | Rio de Janeiro

  • 26 Mar 2027
  • 8 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £246pp

Cruise From:
Was £1721pp Now: £1617pp
View cruise
REF: MSCSP20270326RIORIO
Fly Cruise From:
£1540pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 26 Mar 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £234pp

Fly Cruise From:
£1540pp
View cruise
REF: RCIOV03X042-260327
Fly Cruise From:
£1666pp

6 Night Cabo Overnight & Catalina

Los Angeles | Santa Catalina Island | Cabo San Lucas | Los Angeles

  • 26 Mar 2027
  • 6 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1666pp
View cruise
REF: RCIVY06X023-260327
Cruise From:
Was £1566pp Now: £1519pp

Panama Canal: Miami to Los Angeles

Miami | Cartagena | Colón | Puntarenas | Puerto Quetzal | Cabo San Lucas | Los Angeles

  • 26 Mar 2027
  • 16 Nights
Receive Up to $400 on-board credit on selected sailings
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1566pp Now: £1519pp
View cruise
REF: VIRGINBR270326
Cruise From:
Was £798pp Now: £750pp

South America 7 Nights From Santos

Santos | Buzios | Salvador de Bahia | Maceió | Santos

  • 27 Mar 2027
  • 7 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £105pp

Cruise From:
Was £798pp Now: £750pp
View cruise
REF: MSCVI20270327SSZSSZ
Cruise From:
Was £522pp Now: £506pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 27 Mar 2027
  • 8 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £522pp Now: £506pp
View cruise
REF: CARNIVALPO270320278
Cruise From:
Was £424pp Now: £409pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 27 Mar 2027
  • 7 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £66pp

Cruise From:
Was £424pp Now: £409pp
View cruise
REF: PRINCESSX714
Fly Cruise From:
£2199pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Willemstad | Kralendijk | Oranjestad | Colón

  • 27 Mar 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£2199pp
View cruise
REF: RCIGR07D499-270327
Cruise From:
Was £11070pp Now: £10516pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 27 Mar 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £11070pp Now: £10516pp
View cruise
REF: SILVEROR270327007
Cruise From:
Was £1039pp Now: £997pp

7-Day Mexican Riviera

San Diego | Cabo San Lucas | Mazatlán | Puerto Vallarta | San Diego

  • 27 Mar 2027
  • 7 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £174pp

Cruise From:
Was £1039pp Now: £997pp
View cruise
REF: HALK718A
Cruise From:
Was £1065pp Now: £999pp

Caribbean 11 Nights From Miami, Florida

Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami

  • 28 Mar 2027
  • 11 Nights
Book now with a LOW £50pp deposit! - ends 30th June
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £145pp

Cruise From:
Was £1065pp Now: £999pp
View cruise
REF: MSCPO20270328MIAMIA
Cruise From:
Was £2239pp Now: £2099pp

World-wide 29 Nights From Miami, Florida

Miami | Ocho Rios | Cartagena | Colón | Puerto Limón | Roatán Island | Belize City | Miami | Cartagena | Colón | Cartagena | Colón | Huatulco (Santa María Huatulco) | Cabo San Lucas | San Diego | Los Angeles | Seattle

  • 28 Mar 2027
  • 29 Nights
Book now with a LOW £50pp deposit! - ends 30th June
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £2239pp Now: £2099pp
View cruise
REF: MSCPO20270328MIASEA
Cruise From:
Was £8327pp Now: £7993pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 28 Mar 2027
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £8327pp Now: £7993pp
View cruise
REF: CELEBFL07G059-280327
Cruise From:
Was £372pp Now: £360pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 28 Mar 2027
  • 4 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £372pp Now: £360pp
View cruise
REF: CARNIVALRD280320274
Cruise From:
£585pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 28 Mar 2027
  • 7 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £81pp

Cruise From:
£585pp
View cruise
REF: NCLENC-20270328-07-LAX-LAX
Fly Cruise From:
£2435pp

7 Night Ensenada, Cabo & La Paz Cruise

San Diego | La Paz | Cabo San Lucas | Ensenada | San Diego

  • 28 Mar 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£2435pp
View cruise
REF: RCISR07X069-280327
Cruise From:
Was £1169pp Now: £1122pp

7-Day Mexican Riviera

San Diego | Puerto Vallarta | Mazatlán | Cabo San Lucas | San Diego

  • 28 Mar 2027
  • 7 Nights
  • Zaandam
  • Central America
  • 28 Mar 2027
  • 7 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £194pp

Cruise From:
Was £1169pp Now: £1122pp
View cruise
REF: HALX719
Fly Cruise From:
£2136pp

7 Night Southern Caribbean Cruise

Cartagena | Willemstad | Kralendijk | Oranjestad | Colón | Cartagena

  • 28 Mar 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£2136pp
View cruise
REF: RCIGR7IP231-280327
Cruise From:
Was £369pp Now: £350pp

South America 3 Nights From Santos

Santos | Buzios | Santos

  • 29 Mar 2027
  • 3 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £40pp

Cruise From:
Was £369pp Now: £350pp
View cruise
REF: MSCMU20270329SSZSSZ
Fly Cruise From:
£1788pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 29 Mar 2027
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1788pp
View cruise
REF: RCIOV04X056-290327
Cruise From:
Was £747pp Now: £724pp

Journeys - 16-Day Panama Canal

Mobile | Cartagena | Puntarenas | Cabo San Lucas | Seattle

  • 29 Mar 2027
  • 16 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £747pp Now: £724pp
View cruise
REF: CARNIVALSP2903202716
Cruise From:
Was £450pp Now: £427pp

South America 4 Nights From Salvador de Bahia

Salvador de Bahia | Maceió | Santos

  • 30 Mar 2027
  • 4 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £28pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £52pp

Cruise From:
Was £450pp Now: £427pp
View cruise
REF: MSCVI20270330SSASSZ
Fly Cruise From:
Was £7969pp Now: £7570pp

Carnival Of Caribbean Colors

Panama City | Cartagena | Santa Marta | Oranjestad | Willemstad | Kralendijk | Saint George's | Castries | Gustavia | Tortola | Miami

  • 31 Mar 2027
  • 14 Nights
Fly Cruise From:
Was £7969pp Now: £7570pp
View cruise
REF: REGENTGRA270331
Cruise From:
Was £348pp Now: £330pp

South America 3 Nights From Maceió

Maceió | Santos

  • 31 Mar 2027
  • 3 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £37pp

Cruise From:
Was £348pp Now: £330pp
View cruise
REF: MSCVI20270331MCZSSZ
Cruise From:
Was £1635pp Now: £1536pp

World-wide 21 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Ajaccio | Civitavecchia | Corfu | Bari

  • 31 Mar 2027
  • 21 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £227pp

Cruise From:
Was £1635pp Now: £1536pp
View cruise
REF: MSCSP20270331BUEBRI
Cruise From:
Was £1297pp Now: £1219pp

World-wide 18 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Ajaccio | Civitavecchia

  • 31 Mar 2027
  • 18 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £177pp

Cruise From:
Was £1297pp Now: £1219pp
View cruise
REF: MSCSP20270331BUECVV
Cruise From:
Was £1219pp Now: £1145pp

World-wide 16 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona

  • 31 Mar 2027
  • 16 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £165pp

Cruise From:
Was £1219pp Now: £1145pp
View cruise
REF: MSCSP20270331BUETAR
Cruise From:
Was £1606pp Now: £1499pp

World-wide 22 Nights From Buenos Aires

Buenos Aires | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Ajaccio | Civitavecchia | Corfu | Bari | Trieste

  • 31 Mar 2027
  • 22 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £221pp

Cruise From:
Was £1606pp Now: £1499pp
View cruise
REF: MSCSP20270331BUETRS

Cruise & Stay

Panama Canal with Miami & Seattle Stays

Holiday prices from:
£2679pp

Panama Canal with Miami & Seattle Stays

Fort Lauderdale | Cartagena | Puntarenas | Puerto Quetzal | Huatulco (Santa María Huatulco) | Puerto Vallarta | San Diego | San Francisco | Vancouver | Seattle

  • 01 Apr 2027
  • 26 Nights
  • Eurodam
  • Central America
  • 01 Apr 2027
  • 26 Nights
  • Direct return flights with luggage allowance
  • 4* hotel stays in Miami & Seattle
  • 21-night full-board cruise
  • City Sightseeing Seattle Hop-On Hop-Off Tour
Holiday prices from:
£2679pp
View cruise
Cruise From:
Was £1379pp Now: £1296pp

World-wide 21 Nights From Santos

Santos | Rio de Janeiro | Maceió | Las Palmas de Gran Canaria | Tarragona | Marseille | Genoa | Civitavecchia | Palermo | Ibiza | Valencia

  • 01 Apr 2027
  • 21 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £188pp

Cruise From:
Was £1379pp Now: £1296pp
View cruise
REF: MSCMU20270401SSZVLC

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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