South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2485 cruises
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Cruise From:
£1013pp

7 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Kralendijk | Willemstad | Colón | Cartagena

  • 11 Apr 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £134pp

Cruise From:
£1013pp
View cruise
REF: RCIGR7IP232-110427
Cruise From:
£334pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 12 Apr 2027
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £29pp

Cruise From:
£334pp
View cruise
REF: RCIOV04X056-120427
Cruise From:
£5610pp

A Journey through Enchanting Nature & the Marvels of the Panama Canal

Miami | Ocho Rios | Willemstad | Oranjestad | Santa Marta | Cartagena | Panama City | Cartagena | Panama City

  • 12 Apr 2027
  • 10 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
£5610pp
View cruise
REF: EXPLORAEL20270412MIAAMD
Cruise From:
£12440pp

An Extended Journey from Majestic Horizons to Mayan Gems

Miami | Ocho Rios | Willemstad | Oranjestad | Santa Marta | Cartagena | Panama City | Cartagena | Panama City | Acajutla | Puerto Quetzal | Puerto Madero | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 12 Apr 2027
  • 21 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
£12440pp
View cruise
REF: EXPLORAEL20270412MIALAX
Cruise From:
£303pp

3 Night Ensenada Cruise

San Diego | Ensenada | San Diego

  • 15 Apr 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £24pp

Cruise From:
£303pp
View cruise
REF: RCISR03X044-150427
Cruise From:
£524pp

8 Nt Cabo Overnight, Mazatlan & Ensenada

Los Angeles | Ensenada | Cabo San Lucas | Mazatlán | Los Angeles

  • 15 Apr 2027
  • 8 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £57pp

Cruise From:
£524pp
View cruise
REF: RCIVY08X012-150427
Cruise From:
Was £16668pp Now: £14834pp

46-Day World Cruise: South Pacific & Panama Canal

Brisbane | Norfolk Island | Nouméa | Mystery Island (Inyeug) | Lautoka | Suva | Savusavu | Apia | Honolulu | Kailua-Kona | Long Beach | Puerto Vallarta | Huatulco (Santa María Huatulco) | Puerto Chiapas | Puerto Quetzal | Puntarenas | Cartagena | Miami

  • 15 Apr 2027
  • 46 Nights
Receive up to $1,000 onboard spend per couple
Cruise From:
Was £16668pp Now: £14834pp
View cruise
REF: SBN6728A
Cruise From:
£299pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 16 Apr 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £23pp

Cruise From:
£299pp
View cruise
REF: RCIOV03X041-160427
Cruise From:
Was £424pp Now: £409pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 17 Apr 2027
  • 7 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £59pp

Cruise From:
Was £424pp Now: £409pp
View cruise
REF: PRINCESSX717
Cruise From:
Was £989pp Now: £949pp

6-Day Pacific Coastal Cruise

San Diego | San Francisco | Vancouver

  • 17 Apr 2027
  • 6 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £146pp

Cruise From:
Was £989pp Now: £949pp
View cruise
REF: HALD732C
Cruise From:
£814pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Oranjestad | Willemstad | Colón

  • 17 Apr 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £100pp

Cruise From:
£814pp
View cruise
REF: RCIGR07D494-170427
Cruise From:
Was £10980pp Now: £10431pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | Bartolome Island | Santiago Island | Punta Vicente Roca | Punta Espinoza | Elizabeth Bay | Caleta Tagus | Champion Island | Post Office Bay | Punta Cormorant | Los Gemelos | Puerto Ayora | Santa Cruz Island | Isla Guy Fawkes | Dragon Hill | San Cristóbal Island

  • 17 Apr 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £10980pp Now: £10431pp
View cruise
REF: SILVEROR270417007
Cruise From:
Was £13387pp Now: £12851pp

7 Night Galapagos Outer Loop Cruise

Baltra Island | Punta Suarez | Gardner Bay | Floreana Island | Punta Cormorant | Elizabeth Bay | Urbina Bay | Vincente Roca Point | Punta Espinoza | Daphne Major | South Plaza Island | Dragon Hill | Puerto Ayora | Baltra Island

  • 18 Apr 2027
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £13387pp Now: £12851pp
View cruise
REF: CELEBFL07G060-180427
Cruise From:
Was £307pp Now: £297pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 18 Apr 2027
  • 6 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £307pp Now: £297pp
View cruise
REF: CARNIVALPO180420276
Cruise From:
£341pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 18 Apr 2027
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £29pp

Cruise From:
£341pp
View cruise
REF: RCISR04X058-180427
Fly Cruise From:
Was £4337pp Now: £4163pp

15 Night Panama Canal Westward Cruise

Tampa | Georgetown | Cartagena | Colón | Puntarenas | Puerto Vallarta | Los Angeles

  • 18 Apr 2027
  • 15 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
Was £4337pp Now: £4163pp
View cruise
REF: CELEBSM15C098-180427
Cruise From:
Was £579pp Now: £561pp

Mexican Riviera Cruise

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 18 Apr 2027
  • 7 Nights
Receive Up to $400 on-board credit on selected sailings
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £102pp

Cruise From:
Was £579pp Now: £561pp
View cruise
REF: VIRGINBR270418
Cruise From:
£698pp

6 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Willemstad | Colón

  • 18 Apr 2027
  • 6 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £82pp

Cruise From:
£698pp
View cruise
REF: RCIGR6IP220-180427

Cruise & Stay

Panama Canal: Mexico & Costa Rica with Miami and Los Angeles Stay

Holiday prices from:
£2399pp

Panama Canal: Mexico & Costa Rica with Miami and Los Angeles Stay

Miami | Cartagena | Colón | Puerto Caldera | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles

  • 19 Apr 2027
  • 20 Nights
  • Two-night 4* hotel stays in Miami & Los Angeles
  • Return flights
  • 15-night full-board cruise
Holiday prices from:
£2399pp
View cruise
Cruise From:
Was £924pp Now: £891pp

7-Day Mexican Riviera

Los Angeles | Mazatlán | Cabo San Lucas | Los Angeles

  • 19 Apr 2027
  • 7 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £126pp

Cruise From:
Was £924pp Now: £891pp
View cruise
REF: PRINCESS4716
Cruise From:
£334pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 19 Apr 2027
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £28pp

Cruise From:
£334pp
View cruise
REF: RCIOV04X056-190427
Cruise From:
Was £1790pp Now: £1754pp

Panama Canal: Mexico & Costa Rica

Miami | Cartagena | Colón | Puerto Caldera | Puerto Quetzal | Puerto Vallarta | Cabo San Lucas | Los Angeles

  • 21 Apr 2027
  • 15 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £244pp

Cruise From:
Was £1790pp Now: £1754pp
View cruise
REF: NCLJOY-20270421-15-MIA-LAX
Cruise From:
£302pp

3 Night Ensenada Cruise

San Diego | Ensenada | San Diego

  • 22 Apr 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £23pp

Cruise From:
£302pp
View cruise
REF: RCISR03X050-220427
Cruise From:
£5480pp

A Journey of Mayan Discovery & Mexican Exploration

Panama City | Acajutla | Puerto Quetzal | Puerto Madero | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 22 Apr 2027
  • 11 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
£5480pp
View cruise
REF: EXPLORAEL20270422AMDLAX
Cruise From:
£408pp

6 Night Cabo Overnight & Ensenada

Los Angeles | Cabo San Lucas | Ensenada | Los Angeles

  • 23 Apr 2027
  • 6 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £38pp

Cruise From:
£408pp
View cruise
REF: RCIVY06X024-230427
Cruise From:
£305pp

3 Night Ensenada Getaway Cruise

Los Angeles | Ensenada | Los Angeles

  • 23 Apr 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £23pp

Cruise From:
£305pp
View cruise
REF: RCIOV03X053-230427
Cruise From:
Was £422pp Now: £409pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 24 Apr 2027
  • 8 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £422pp Now: £409pp
View cruise
REF: CARNIVALPO240420278
Cruise From:
Was £424pp Now: £409pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 24 Apr 2027
  • 7 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £56pp

Cruise From:
Was £424pp Now: £409pp
View cruise
REF: PRINCESSX718
Cruise From:
Was £9230pp Now: £8860pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 25 Apr 2027
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £9230pp Now: £8860pp
View cruise
REF: CELEBFL07G059-250427
Cruise From:
Was £286pp Now: £277pp

4-Day Baja Mexico

Long Beach | Santa Catalina Island | Ensenada | Long Beach

  • 25 Apr 2027
  • 4 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £286pp Now: £277pp
View cruise
REF: CARNIVALRD250420274

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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