South America Cruise Deals

There's so much to explore on a cruise around South America, from sun-drenched coastal resorts and cosmopolitan cities, to lush rainforests and UNESCO world heritage sites. To find out more and discover the very best deals and prices call us today and speak to our cruise holiday experts.

Find Out More About Cruising South America

Showing 30 out of 2485 cruises
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Cruise From:
Was £954pp Now: £920pp

16-Day Panama Canal - Ocean to Ocean

Fort Lauderdale | Cartagena | Fuerte Amador | Puntarenas | Puerto Chiapas | Huatulco (Santa María Huatulco) | Puerto Vallarta | Los Angeles

  • 04 Apr 2027
  • 16 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £141pp

Cruise From:
Was £954pp Now: £920pp
View cruise
REF: PRINCESS3715
Cruise From:
Was £1959pp Now: £1880pp

13-Day Historical Baja Peninsula

San Diego | Cabo San Lucas | Loreto | Guaymas | Topolobampo | La Paz | Mazatlán | Puerto Vallarta | Manzanillo | Ensenada | San Diego

  • 04 Apr 2027
  • 13 Nights
  • Zaandam
  • Central America
  • 04 Apr 2027
  • 13 Nights
Upgrade to Have It All from £60pp per night and receive Drinks, Wi-Fi, Speciality Dining and more
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1959pp Now: £1880pp
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REF: HALX720
Cruise From:
Was £352pp Now: £341pp

6-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 04 Apr 2027
  • 6 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £352pp Now: £341pp
View cruise
REF: CARNIVALPO040420276
Cruise From:
£590pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 04 Apr 2027
  • 7 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £79pp

Cruise From:
£590pp
View cruise
REF: NCLENC-20270404-07-LAX-LAX
Cruise From:
£341pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 04 Apr 2027
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £31pp

Cruise From:
£341pp
View cruise
REF: RCISR04X058-040427
Cruise From:
Was £870pp Now: £843pp

Journeys - 16-Day Panama Canal

Tampa | Santa Marta | Cartagena | Acapulco | Cabo San Lucas | Seattle

  • 04 Apr 2027
  • 16 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £870pp Now: £843pp
View cruise
REF: CARNIVALLE0404202716
Cruise From:
£812pp

7 Night Southern Caribbean Cruise

Cartagena | Oranjestad | Willemstad | Colón | Cartagena

  • 04 Apr 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £106pp

Cruise From:
£812pp
View cruise
REF: RCIGR7IP226-040427
Cruise From:
Was £3819pp Now: £3589pp

World-wide 12 Nights From Maceió

Maceió | Las Palmas de Gran Canaria | Tarragona | Marseille | Genoa

  • 05 Apr 2027
  • 12 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £3819pp Now: £3589pp
View cruise
REF: MSCMU20270405MCZGOA
Fly Cruise From:
£1747pp

4 Night Catalina & Ensenada Cruise

Los Angeles | Santa Catalina Island | Ensenada | Los Angeles

  • 05 Apr 2027
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1747pp
View cruise
REF: RCIOV04X056-050427
Cruise From:
Was £1510pp Now: £1479pp

Panama Canal: Mexico, Jamaica & Costa Rica

Miami | Ocho Rios | Cartagena | Colón | Gatun Lake | Puerto Limón | Harvest Caye | Cozumel | Miami

  • 05 Apr 2027
  • 11 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £220pp

Cruise From:
Was £1510pp Now: £1479pp
View cruise
REF: NCLSUN-20270405-11-MIA-MIA
Cruise From:
£9750pp

A Grand Journey through Balmy Shores & Enchanting Nature to Panama’s Wonders

San Juan (Puerto Rico) | Gustavia | Little Bay | Basseterre | Key West | Miami | Ocho Rios | Willemstad | Oranjestad | Santa Marta | Cartagena | Panama City | Cartagena | Panama City

  • 05 Apr 2027
  • 17 Nights
Save up to 25% PLUS up to £2600 Explora Credit
Cruise From:
£9750pp
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REF: EXPLORAEL20270405SJUAMD
Cruise From:
Was £335pp Now: £324pp

5-Day Mexican Riviera

Long Beach | Cabo San Lucas | Ensenada | Long Beach

  • 06 Apr 2027
  • 5 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £335pp Now: £324pp
View cruise
REF: CARNIVALRD060420275
Cruise From:
Was £7989pp Now: £7099pp

21-Day South America, Canary Islands & Spain

Rio de Janeiro | Salvador de Bahia | Recife | Natal | Praia | Mindelo | Tenerife | Arrecife | Tangier | Seville

  • 06 Apr 2027
  • 21 Nights
Save up to 15% for a limited time ONLY!
Cruise From:
Was £7989pp Now: £7099pp
View cruise
REF: SBNV726
Cruise From:
Was £12239pp Now: £10892pp

31-Day South America, Canary Islands, Spain & France

Rio de Janeiro | Salvador de Bahia | Recife | Natal | Praia | Mindelo | Tenerife | Arrecife | Tangier | Seville | Porto | Vigo | Brest | Saint-Malo | Cherbourg | Rouen | Cherbourg | Amsterdam

  • 06 Apr 2027
  • 31 Nights
Save up to 15% for a limited time ONLY!
Cruise From:
Was £12239pp Now: £10892pp
View cruise
REF: SBNV726A
Cruise From:
Was £1049pp Now: £986pp

World-wide 13 Nights From Salvador de Bahia

Salvador de Bahia | Maceió | Santa Cruz de Tenerife | Tangier | Barcelona

  • 07 Apr 2027
  • 13 Nights
Book now with a LOW £50pp deposit! - ends 30th June
Save & Sail! Save up to £540 per cabin
Summer 2027 flights now on sale!
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £136pp

Cruise From:
Was £1049pp Now: £986pp
View cruise
REF: MSCVI20270407SSABCN
Cruise From:
Was £11559pp Now: £10287pp

19-Day Easter & Pitcairn Islands: Marooned, Moai & Mutineers

San Antonio | Juan Fernández Island | Hangaroa | Ducie Island | Pitcairn Island | Fakarava | Tahanea | Anaa | Papeete

  • 07 Apr 2027
  • 19 Nights
Save up to 15% for a limited time ONLY!
Cruise From:
Was £11559pp Now: £10287pp
View cruise
REF: SBNP726
Cruise From:
Was £1365pp Now: £1283pp

World-wide 18 Nights From Miami, Florida

Miami | Cartagena | Colón | Huatulco (Santa María Huatulco) | Cabo San Lucas | San Diego | Los Angeles | Seattle

  • 08 Apr 2027
  • 18 Nights
Book now with a LOW £50pp deposit! - ends 30th June
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
FREE Balcony Upgrades! Book a Balcony Cabin for the price of an Ocean View
Save & Sail! Save up to £540 per cabin
Reduced Premium Drinks Package from just £26pp per day
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £180pp

Cruise From:
Was £1365pp Now: £1283pp
View cruise
REF: MSCPO20270408MIASEA
Cruise From:
£303pp

3 Night Ensenada Cruise

San Diego | Ensenada | San Diego

  • 08 Apr 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £24pp

Cruise From:
£303pp
View cruise
REF: RCISR03X044-080427
Fly Cruise From:
£1705pp

3 Night Ensenada Cruise

Los Angeles | Ensenada | Los Angeles

  • 09 Apr 2027
  • 3 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £243pp

Fly Cruise From:
£1705pp
View cruise
REF: RCIOV03X041-090427
Fly Cruise From:
£1823pp

6 Night Cabo Overnight & Ensenada

Los Angeles | Cabo San Lucas | Ensenada | Los Angeles

  • 09 Apr 2027
  • 6 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available
Fly Cruise From:
£1823pp
View cruise
REF: RCIVY06X022-090427
Cruise From:
Was £1805pp Now: £1768pp

Panama Canal: Mexico & Costa Rica

New York | Puerto Plata | Cartagena | Colón | Puerto Caldera | Puerto Quetzal | Acapulco | Puerto Vallarta | Cabo San Lucas | San Francisco

  • 09 Apr 2027
  • 19 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1805pp Now: £1768pp
View cruise
REF: NCLBLS-20270409-19-NYC-SFO
Cruise From:
Was £1920pp Now: £1881pp

Panama Canal: Mexico & Costa Rica

New York | Puerto Plata | Cartagena | Colón | Puerto Caldera | Puerto Quetzal | Acapulco | Puerto Vallarta | Cabo San Lucas | San Francisco | Victoria | Seattle

  • 09 Apr 2027
  • 22 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £1920pp Now: £1881pp
View cruise
REF: NCLBLS-20270409-22-NYC-SEA
Cruise From:
Was £429pp Now: £416pp

8-Day Mexican Riviera

Long Beach | Puerto Vallarta | Mazatlán | La Paz | Cabo San Lucas | Long Beach

  • 10 Apr 2027
  • 8 Nights
Live availability and prices when you book online with Cruise118.com
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £429pp Now: £416pp
View cruise
REF: CARNIVALPO100420278
Cruise From:
Was £444pp Now: £428pp

7-Day Mexican Riviera

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 10 Apr 2027
  • 7 Nights
Cruise118.com Exclusive! LOW £50pp Deposit PLUS Receive an on-board coupon booklet worth over $900 - ends 23rd June
Signature Savings! Includes up to £750 OFF per stateroom - ends 14th July
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £64pp

Cruise From:
Was £444pp Now: £428pp
View cruise
REF: PRINCESSX716
Cruise From:
£899pp

7 Night Southern Caribbean Cruise

Colón | Cartagena | Oranjestad | Kralendijk | Willemstad | Colón

  • 10 Apr 2027
  • 7 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £117pp

Cruise From:
£899pp
View cruise
REF: RCIGR07D500-100427
Cruise From:
Was £11340pp Now: £10773pp

San Cristóbal to San Cristóbal

San Cristóbal Island | Roca León Dormido | El Barranco | Darwin Bay | Sullivan Bay | North Seymour Island | Punta Moreno | Mangle Point | Los Gemelos | Puerto Ayora | Punta Suarez | Gardner Bay | Cerro Brujo | San Cristóbal Island

  • 10 Apr 2027
  • 7 Nights
Save up to 40% PLUS deposits from 15%*
Cruise From:
Was £11340pp Now: £10773pp
View cruise
REF: SILVEROR270410007
Cruise From:
Was £9160pp Now: £8793pp

7 Night Galapagos Inner Loop Cruise

Baltra Island | Rabida Island | Puerto Egas | Elizabeth Bay | Tagus Cove | Bartolome Island | Sullivan Bay | Daphne Major | North Seymour Island | Las Bachas | Punta Pitt | Puerto Baquerizo Moreno | Puerto Ayora | Baltra Island

  • 11 Apr 2027
  • 7 Nights
At least 60% OFF 2nd guest PLUS up to £1000 OFF per stateroom
Book online for EXTRA savings, best prices and live availability - limited time offers available
Cruise From:
Was £9160pp Now: £8793pp
View cruise
REF: CELEBFL07G059-110427
Cruise From:
£341pp

4 Night Catalina & Ensenada Cruise

San Diego | Santa Catalina Island | Ensenada | San Diego

  • 11 Apr 2027
  • 4 Nights
HUGE savings up to £675 OFF per stateroom + 3rd & 4th guest from £99pp
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £30pp

Cruise From:
£341pp
View cruise
REF: RCISR04X058-110427
Cruise From:
£635pp

Mexican Riviera: Cabo San Lucas & Puerto Vallarta

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 11 Apr 2027
  • 7 Nights
Upgrade to Free at Sea from £249pp and receive Premium Beverages, Wi-Fi, Speciality Dining and more!
Receive up to £250pp airfare credit!
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £83pp

Cruise From:
£635pp
View cruise
REF: NCLENC-20270411-07-LAX-LAX
Cruise From:
Was £579pp Now: £561pp

Mexican Riviera Cruise

Los Angeles | Cabo San Lucas | Mazatlán | Puerto Vallarta | Los Angeles

  • 11 Apr 2027
  • 7 Nights
Receive Up to $400 on-board credit on selected sailings
Book online for EXTRA savings, best prices and live availability - limited time offers available

Interest free Monthly Payments from JUST £108pp

Cruise From:
Was £579pp Now: £561pp
View cruise
REF: VIRGINBR270411

Prices are subject to change and availability. Prices may vary depending on the airport selected. Promotions are only applicable to select cabin grades, please call for details.

With such a vast number of itineraries to choose from, it can be beneficial to enlist the help of an expert to help you find the best deals. Our Cruise Concierge team can search through all the available cruise offers to help you book your South American cruise holiday at the very best price. Just give us a call.

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This website will provide you with information on the financial protection that applies in the case of each holiday and travel service offered before you make your booking. At the time of booking, our Cruise Concierge will also confirm the financial protection applicable to your specific holiday. Please ask us for further information should you require it. The flight inclusive holidays on this website are financially protected by the ATOL scheme. But ATOL protection does not apply to all holiday and travel services listed on this website. If you do not receive an ATOL Certificate then the booking will not be ATOL protected. If you do receive an ATOL Certificate but all parts of your trip are not listed on it, those parts will not be ATOL protected. The cruise-only holidays on this website are financially protected by ABTA. Please see our booking terms and conditions for further information or for more information about financial protection and the ATOL Certificate, click here. Cruise118 acts as a retail agent to you and also as a disclosed agent of the holiday provider (the Organiser of the holiday). The Foreign & Commonwealth Office have up-to-date advice on staying safe and healthy abroad. Visit the foreign travel advice site for the latest travel updates.
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